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SEC24B (SEC24 homolog B, COPII coat complex component)

Identity

Alias_namesSEC24 (S. cerevisiae) related gene family, member B
SEC24 family, member B (S. cerevisiae)
SEC24 family member B
Other aliasSEC24
HGNC (Hugo) SEC24B
LocusID (NCBI) 10427
Atlas_Id 73092
Location 4q25  [Link to chromosome band 4q25]
Location_base_pair Starts at 109433715 and ends at 109540459 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SEC24B (4q25) / MALAT1 (11q13.1)SEC24B (4q25) / SEC24B (4q25)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC24B   10704
Cards
Entrez_Gene (NCBI)SEC24B  10427  SEC24 homolog B, COPII coat complex component
AliasesSEC24
GeneCards (Weizmann)SEC24B
Ensembl hg19 (Hinxton)ENSG00000138802 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138802 [Gene_View]  chr4:109433715-109540459 [Contig_View]  SEC24B [Vega]
ICGC DataPortalENSG00000138802
TCGA cBioPortalSEC24B
AceView (NCBI)SEC24B
Genatlas (Paris)SEC24B
WikiGenes10427
SOURCE (Princeton)SEC24B
Genetics Home Reference (NIH)SEC24B
Genomic and cartography
GoldenPath hg38 (UCSC)SEC24B  -     chr4:109433715-109540459 +  4q25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEC24B  -     4q25   [Description]    (hg19-Feb_2009)
EnsemblSEC24B - 4q25 [CytoView hg19]  SEC24B - 4q25 [CytoView hg38]
Mapping of homologs : NCBISEC24B [Mapview hg19]  SEC24B [Mapview hg38]
OMIM607184   
Gene and transcription
Genbank (Entrez)AA194999 AI193145 AJ131245 AK300278 AK304234
RefSeq transcript (Entrez)NM_001042734 NM_001300813 NM_001318085 NM_001318086 NM_006323
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEC24B
Cluster EST : UnigeneHs.292472 [ NCBI ]
CGAP (NCI)Hs.292472
Alternative Splicing GalleryENSG00000138802
Gene ExpressionSEC24B [ NCBI-GEO ]   SEC24B [ EBI - ARRAY_EXPRESS ]   SEC24B [ SEEK ]   SEC24B [ MEM ]
Gene Expression Viewer (FireBrowse)SEC24B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10427
GTEX Portal (Tissue expression)SEC24B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95487   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95487  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95487
Splice isoforms : SwissVarO95487
PhosPhoSitePlusO95487
Domains : Interpro (EBI)ADF-H/Gelsolin-like_dom    Gelsolin-like_dom    Sec23/24_helical_dom    Sec23/24_trunk_dom    Sec23_24_beta_S    VWF_A    Znf_Sec23_Sec24   
Domain families : Pfam (Sanger)Gelsolin (PF00626)    Sec23_BS (PF08033)    Sec23_helical (PF04815)    Sec23_trunk (PF04811)    zf-Sec23_Sec24 (PF04810)   
Domain families : Pfam (NCBI)pfam00626    pfam08033    pfam04815    pfam04811    pfam04810   
Conserved Domain (NCBI)SEC24B
DMDM Disease mutations10427
Blocks (Seattle)SEC24B
PDB (SRS)3EH1   
PDB (PDBSum)3EH1   
PDB (IMB)3EH1   
PDB (RSDB)3EH1   
Structural Biology KnowledgeBase3EH1   
SCOP (Structural Classification of Proteins)3EH1   
CATH (Classification of proteins structures)3EH1   
SuperfamilyO95487
Human Protein AtlasENSG00000138802
Peptide AtlasO95487
HPRD06216
IPIIPI00030851   IPI00785208   IPI00981087   
Protein Interaction databases
DIP (DOE-UCLA)O95487
IntAct (EBI)O95487
FunCoupENSG00000138802
BioGRIDSEC24B
STRING (EMBL)SEC24B
ZODIACSEC24B
Ontologies - Pathways
QuickGOO95487
Ontology : AmiGOGolgi membrane  neural tube closure  antigen processing and presentation of peptide antigen via MHC class I  outflow tract morphogenesis  transporter activity  protein binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  zinc ion binding  ER to Golgi transport vesicle membrane  membrane  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  cochlear nucleus development  COPII vesicle coat  ER to Golgi transport vesicle  aorta morphogenesis  COPII vesicle coating  perinuclear region of cytoplasm  auditory receptor cell stereocilium organization  lung lobe morphogenesis  coronary artery morphogenesis  pulmonary artery morphogenesis  regulation of establishment of planar polarity involved in neural tube closure  regulation of cargo loading into COPII-coated vesicle  
Ontology : EGO-EBIGolgi membrane  neural tube closure  antigen processing and presentation of peptide antigen via MHC class I  outflow tract morphogenesis  transporter activity  protein binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  zinc ion binding  ER to Golgi transport vesicle membrane  membrane  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  cochlear nucleus development  COPII vesicle coat  ER to Golgi transport vesicle  aorta morphogenesis  COPII vesicle coating  perinuclear region of cytoplasm  auditory receptor cell stereocilium organization  lung lobe morphogenesis  coronary artery morphogenesis  pulmonary artery morphogenesis  regulation of establishment of planar polarity involved in neural tube closure  regulation of cargo loading into COPII-coated vesicle  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkSEC24B
Atlas of Cancer Signalling NetworkSEC24B
Wikipedia pathwaysSEC24B
Orthology - Evolution
OrthoDB10427
GeneTree (enSembl)ENSG00000138802
Phylogenetic Trees/Animal Genes : TreeFamSEC24B
HOVERGENO95487
HOGENOMO95487
Homologs : HomoloGeneSEC24B
Homology/Alignments : Family Browser (UCSC)SEC24B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC24B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC24B
dbVarSEC24B
ClinVarSEC24B
1000_GenomesSEC24B 
Exome Variant ServerSEC24B
ExAC (Exome Aggregation Consortium)SEC24B (select the gene name)
Genetic variants : HAPMAP10427
Genomic Variants (DGV)SEC24B [DGVbeta]
DECIPHERSEC24B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEC24B 
Mutations
ICGC Data PortalSEC24B 
TCGA Data PortalSEC24B 
Broad Tumor PortalSEC24B
OASIS PortalSEC24B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC24B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEC24B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch SEC24B
DgiDB (Drug Gene Interaction Database)SEC24B
DoCM (Curated mutations)SEC24B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC24B (select a term)
intoGenSEC24B
Cancer3DSEC24B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607184   
Orphanet
MedgenSEC24B
Genetic Testing Registry SEC24B
NextProtO95487 [Medical]
TSGene10427
GENETestsSEC24B
Target ValidationSEC24B
Huge Navigator SEC24B [HugePedia]
snp3D : Map Gene to Disease10427
BioCentury BCIQSEC24B
ClinGenSEC24B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10427
Chemical/Pharm GKB GenePA35627
Clinical trialSEC24B
Miscellaneous
canSAR (ICR)SEC24B (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC24B
EVEXSEC24B
GoPubMedSEC24B
iHOPSEC24B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:40:17 CEST 2017

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