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SEC61A2 (Sec61 alpha 2 subunit (S. cerevisiae))

Identity

Alias_namesSec61 alpha 2 subunit (S. cerevisiae)
Alias_symbol (synonym)FLJ10578
Other alias-
HGNC (Hugo) SEC61A2
LocusID (NCBI) 55176
Atlas_Id 73097
Location 10p14  [Link to chromosome band 10p14]
Location_base_pair Starts at 12171640 and ends at 12211957 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SEC61A2 (10p14) / SEC61A2 (10p14)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC61A2   17702
Cards
Entrez_Gene (NCBI)SEC61A2  55176  Sec61 alpha 2 subunit (S. cerevisiae)
Aliases
GeneCards (Weizmann)SEC61A2
Ensembl hg19 (Hinxton)ENSG00000065665 [Gene_View]  chr10:12171640-12211957 [Contig_View]  SEC61A2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000065665 [Gene_View]  chr10:12171640-12211957 [Contig_View]  SEC61A2 [Vega]
ICGC DataPortalENSG00000065665
TCGA cBioPortalSEC61A2
AceView (NCBI)SEC61A2
Genatlas (Paris)SEC61A2
WikiGenes55176
SOURCE (Princeton)SEC61A2
Genetics Home Reference (NIH)SEC61A2
Genomic and cartography
GoldenPath hg19 (UCSC)SEC61A2  -     chr10:12171640-12211957 +  10p14   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SEC61A2  -     10p14   [Description]    (hg38-Dec_2013)
EnsemblSEC61A2 - 10p14 [CytoView hg19]  SEC61A2 - 10p14 [CytoView hg38]
Mapping of homologs : NCBISEC61A2 [Mapview hg19]  SEC61A2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF346603 AK001440 AK022027 AK022640 AK057532
RefSeq transcript (Entrez)NM_001142627 NM_001142628 NM_018144
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_008705 NW_004929370
Consensus coding sequences : CCDS (NCBI)SEC61A2
Cluster EST : UnigeneHs.112955 [ NCBI ]
CGAP (NCI)Hs.112955
Alternative Splicing GalleryENSG00000065665
Gene ExpressionSEC61A2 [ NCBI-GEO ]   SEC61A2 [ EBI - ARRAY_EXPRESS ]   SEC61A2 [ SEEK ]   SEC61A2 [ MEM ]
Gene Expression Viewer (FireBrowse)SEC61A2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55176
GTEX Portal (Tissue expression)SEC61A2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H9S3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H9S3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H9S3
Splice isoforms : SwissVarQ9H9S3
PhosPhoSitePlusQ9H9S3
Domaine pattern : Prosite (Expaxy)SECY_1 (PS00755)    SECY_2 (PS00756)   
Domains : Interpro (EBI)SecY/SEC61-alpha    SecY_CS    SecY_su_dom    Translocon_Sec61/SecY_plug_dom   
Domain families : Pfam (Sanger)Plug_translocon (PF10559)    SecY (PF00344)   
Domain families : Pfam (NCBI)pfam10559    pfam00344   
Conserved Domain (NCBI)SEC61A2
DMDM Disease mutations55176
Blocks (Seattle)SEC61A2
SuperfamilyQ9H9S3
Human Protein AtlasENSG00000065665
Peptide AtlasQ9H9S3
HPRD15317
IPIIPI00414427   IPI00414428   IPI00182313   IPI00647396   IPI00647854   IPI00854697   IPI00644876   IPI00982948   IPI00640481   IPI00935795   IPI01012446   IPI00640009   
Protein Interaction databases
DIP (DOE-UCLA)Q9H9S3
IntAct (EBI)Q9H9S3
FunCoupENSG00000065665
BioGRIDSEC61A2
STRING (EMBL)SEC61A2
ZODIACSEC61A2
Ontologies - Pathways
QuickGOQ9H9S3
Ontology : AmiGOantigen processing and presentation of peptide antigen via MHC class I  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  molecular_function  endoplasmic reticulum membrane  cytosol  biological_process  protein transport  integral component of membrane  endoplasmic reticulum unfolded protein response  IRE1-mediated unfolded protein response  antigen processing and presentation of exogenous peptide antigen via MHC class I  ribosome binding  cellular protein metabolic process  
Ontology : EGO-EBIantigen processing and presentation of peptide antigen via MHC class I  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  molecular_function  endoplasmic reticulum membrane  cytosol  biological_process  protein transport  integral component of membrane  endoplasmic reticulum unfolded protein response  IRE1-mediated unfolded protein response  antigen processing and presentation of exogenous peptide antigen via MHC class I  ribosome binding  cellular protein metabolic process  
Pathways : KEGGProtein export    Protein processing in endoplasmic reticulum    Phagosome    Vibrio cholerae infection   
NDEx NetworkSEC61A2
Atlas of Cancer Signalling NetworkSEC61A2
Wikipedia pathwaysSEC61A2
Orthology - Evolution
OrthoDB55176
GeneTree (enSembl)ENSG00000065665
Phylogenetic Trees/Animal Genes : TreeFamSEC61A2
HOVERGENQ9H9S3
HOGENOMQ9H9S3
Homologs : HomoloGeneSEC61A2
Homology/Alignments : Family Browser (UCSC)SEC61A2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC61A2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC61A2
dbVarSEC61A2
ClinVarSEC61A2
1000_GenomesSEC61A2 
Exome Variant ServerSEC61A2
ExAC (Exome Aggregation Consortium)SEC61A2 (select the gene name)
Genetic variants : HAPMAP55176
Genomic Variants (DGV)SEC61A2 [DGVbeta]
DECIPHER (Syndromes)10:12171640-12211957  ENSG00000065665
CONAN: Copy Number AnalysisSEC61A2 
Mutations
ICGC Data PortalSEC61A2 
TCGA Data PortalSEC61A2 
Broad Tumor PortalSEC61A2
OASIS PortalSEC61A2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC61A2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEC61A2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEC61A2
DgiDB (Drug Gene Interaction Database)SEC61A2
DoCM (Curated mutations)SEC61A2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC61A2 (select a term)
intoGenSEC61A2
Cancer3DSEC61A2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSEC61A2
Genetic Testing Registry SEC61A2
NextProtQ9H9S3 [Medical]
TSGene55176
GENETestsSEC61A2
Huge Navigator SEC61A2 [HugePedia]
snp3D : Map Gene to Disease55176
BioCentury BCIQSEC61A2
ClinGenSEC61A2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55176
Chemical/Pharm GKB GenePA134861382
Clinical trialSEC61A2
Miscellaneous
canSAR (ICR)SEC61A2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC61A2
EVEXSEC61A2
GoPubMedSEC61A2
iHOPSEC61A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 12:42:43 CET 2017

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