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SEC61B (Sec61 beta subunit)

Identity

Other names-
HGNC (Hugo) SEC61B
LocusID (NCBI) 10952
Location 9q22.33
Location_base_pair Starts at 101984570 and ends at 101992901 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SEC61B   16993
Cards
Entrez_Gene (NCBI)SEC61B  10952  Sec61 beta subunit
GeneCards (Weizmann)SEC61B
Ensembl hg19 (Hinxton)ENSG00000106803 [Gene_View]  chr9:101984570-101992901 [Contig_View]  SEC61B [Vega]
Ensembl hg38 (Hinxton)ENSG00000106803 [Gene_View]  chr9:101984570-101992901 [Contig_View]  SEC61B [Vega]
ICGC DataPortalENSG00000106803
cBioPortalSEC61B
AceView (NCBI)SEC61B
Genatlas (Paris)SEC61B
WikiGenes10952
SOURCE (Princeton)SEC61B
Genomic and cartography
GoldenPath hg19 (UCSC)SEC61B  -     chr9:101984570-101992901 +  9q22.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SEC61B  -     9q22.33   [Description]    (hg38-Dec_2013)
EnsemblSEC61B - 9q22.33 [CytoView hg19]  SEC61B - 9q22.33 [CytoView hg38]
Mapping of homologs : NCBISEC61B [Mapview hg19]  SEC61B [Mapview hg38]
OMIM609214   
Gene and transcription
Genbank (Entrez)AJ293399 AK223384 BC001734 CR456883 CR542159
RefSeq transcript (Entrez)NM_006808
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NT_008470 NW_001839236 NW_004929366
Consensus coding sequences : CCDS (NCBI)SEC61B
Cluster EST : UnigeneHs.191887 [ NCBI ]
CGAP (NCI)Hs.191887
Alternative Splicing : Fast-db (Paris)GSHG0030314
Alternative Splicing GalleryENSG00000106803
Gene ExpressionSEC61B [ NCBI-GEO ]     SEC61B [ SEEK ]   SEC61B [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP60468 (Uniprot)
NextProtP60468  [Medical]
With graphics : InterProP60468
Splice isoforms : SwissVarP60468 (Swissvar)
Domains : Interpro (EBI)SecG/Sec61-beta/Sbh1   
Related proteins : CluSTrP60468
Domain families : Pfam (Sanger)Sec61_beta (PF03911)   
Domain families : Pfam (NCBI)pfam03911   
DMDM Disease mutations10952
Blocks (Seattle)P60468
Human Protein AtlasENSG00000106803
Peptide AtlasP60468
HPRD06715
IPIIPI00220835   
Protein Interaction databases
DIP (DOE-UCLA)P60468
IntAct (EBI)P60468
FunCoupENSG00000106803
BioGRIDSEC61B
IntegromeDBSEC61B
STRING (EMBL)SEC61B
Ontologies - Pathways
QuickGOP60468
Ontology : AmiGOprotein import into nucleus, translocation  antigen processing and presentation of peptide antigen via MHC class I  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  endoplasmic reticulum  translation  SRP-dependent cotranslational protein targeting to membrane  gene expression  membrane  integral component of membrane  ER-associated ubiquitin-dependent protein catabolic process  retrograde protein transport, ER to cytosol  endoplasmic reticulum Sec complex  antigen processing and presentation of exogenous peptide antigen via MHC class I  ribosome binding  cellular protein metabolic process  poly(A) RNA binding  epidermal growth factor binding  
Ontology : EGO-EBIprotein import into nucleus, translocation  antigen processing and presentation of peptide antigen via MHC class I  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  endoplasmic reticulum  translation  SRP-dependent cotranslational protein targeting to membrane  gene expression  membrane  integral component of membrane  ER-associated ubiquitin-dependent protein catabolic process  retrograde protein transport, ER to cytosol  endoplasmic reticulum Sec complex  antigen processing and presentation of exogenous peptide antigen via MHC class I  ribosome binding  cellular protein metabolic process  poly(A) RNA binding  epidermal growth factor binding  
Pathways : KEGGProtein export    Protein processing in endoplasmic reticulum    Phagosome    Vibrio cholerae infection   
Protein Interaction DatabaseSEC61B
DoCM (Curated mutations)SEC61B
Wikipedia pathwaysSEC61B
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSEC61B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC61B
dbVarSEC61B
ClinVarSEC61B
1000_GenomesSEC61B 
Exome Variant ServerSEC61B
SNP (GeneSNP Utah)SEC61B
SNP : HGBaseSEC61B
Genetic variants : HAPMAPSEC61B
Genomic VariantsSEC61B  SEC61B [DGVbeta]
Mutations
ICGC Data PortalENSG00000106803 
Somatic Mutations in Cancer : COSMICSEC61B 
CONAN: Copy Number AnalysisSEC61B 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)9:101984570-101992901
Mutations and Diseases : HGMDSEC61B
OMIM609214   
MedgenSEC61B
NextProtP60468 [Medical]
GENETestsSEC61B
Disease Genetic AssociationSEC61B
Huge Navigator SEC61B [HugePedia]  SEC61B [HugeCancerGEM]
snp3D : Map Gene to Disease10952
DGIdb (Drug Gene Interaction db)SEC61B
General knowledge
Homologs : HomoloGeneSEC61B
Homology/Alignments : Family Browser (UCSC)SEC61B
Phylogenetic Trees/Animal Genes : TreeFamSEC61B
Chemical/Protein Interactions : CTD10952
Chemical/Pharm GKB GenePA134888963
Clinical trialSEC61B
Cancer Resource (Charite)ENSG00000106803
Other databases
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
CoreMineSEC61B
GoPubMedSEC61B
iHOPSEC61B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 01:21:06 CET 2014

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