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SEC63 (SEC63 homolog (S. cerevisiae))

Identity

Other namesDNAJC23
ERdj2
PRO2507
SEC63L
HGNC (Hugo) SEC63
LocusID (NCBI) 11231
Atlas_Id 42242
Location 6q21
Location_base_pair Starts at 108188960 and ends at 108279482 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SEC63   21082
Cards
Entrez_Gene (NCBI)SEC63  11231  SEC63 homolog (S. cerevisiae)
GeneCards (Weizmann)SEC63
Ensembl hg19 (Hinxton)ENSG00000025796 [Gene_View]  chr6:108188960-108279482 [Contig_View]  SEC63 [Vega]
Ensembl hg38 (Hinxton)ENSG00000025796 [Gene_View]  chr6:108188960-108279482 [Contig_View]  SEC63 [Vega]
ICGC DataPortalENSG00000025796
TCGA cBioPortalSEC63
AceView (NCBI)SEC63
Genatlas (Paris)SEC63
WikiGenes11231
SOURCE (Princeton)SEC63
Genomic and cartography
GoldenPath hg19 (UCSC)SEC63  -     chr6:108188960-108279482 -  6q21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SEC63  -     6q21   [Description]    (hg38-Dec_2013)
EnsemblSEC63 - 6q21 [CytoView hg19]  SEC63 - 6q21 [CytoView hg38]
Mapping of homologs : NCBISEC63 [Mapview hg19]  SEC63 [Mapview hg38]
OMIM174050   608648   
Gene and transcription
Genbank (Entrez)AF100141 AF119883 AI559292 AJ011779 AJ420532
RefSeq transcript (Entrez)NM_007214 NM_018529
RefSeq genomic (Entrez)NC_000006 NC_018917 NG_008270 NT_025741 NW_004929328
Consensus coding sequences : CCDS (NCBI)SEC63
Cluster EST : UnigeneHs.26904 [ NCBI ]
CGAP (NCI)Hs.26904
Alternative Splicing : Fast-db (Paris)GSHG0026822
Alternative Splicing GalleryENSG00000025796
Gene ExpressionSEC63 [ NCBI-GEO ]     SEC63 [ SEEK ]   SEC63 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UGP8 (Uniprot)
NextProtQ9UGP8  [Medical]  [Publications]
With graphics : InterProQ9UGP8
Splice isoforms : SwissVarQ9UGP8 (Swissvar)
Domaine pattern : Prosite (Expaxy)DNAJ_2 (PS50076)   
Domains : Interpro (EBI)C2_dom    DnaJ_domain    Ig_E-set    Sec63    Sec63-dom   
Related proteins : CluSTrQ9UGP8
Domain families : Pfam (Sanger)DnaJ (PF00226)    Sec63 (PF02889)   
Domain families : Pfam (NCBI)pfam00226    pfam02889   
Domain families : Smart (EMBL)DnaJ (SM00271)  SEC63 (SM00611)  Sec63 (SM00973)  
DMDM Disease mutations11231
Blocks (Seattle)Q9UGP8
Human Protein AtlasENSG00000025796
Peptide AtlasQ9UGP8
HPRD09783
IPIIPI00218922   IPI00902496   IPI00903261   IPI00383314   IPI00852625   IPI00893574   
Protein Interaction databases
DIP (DOE-UCLA)Q9UGP8
IntAct (EBI)Q9UGP8
FunCoupENSG00000025796
BioGRIDSEC63
IntegromeDBSEC63
STRING (EMBL)SEC63
Ontologies - Pathways
QuickGOQ9UGP8
Ontology : AmiGOliver development  receptor activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  cytosol  protein targeting to membrane  SRP-dependent cotranslational protein targeting to membrane  posttranslational protein targeting to membrane  nitrogen compound metabolic process  protein transporter activity  multicellular organismal aging  membrane  integral component of membrane  endoplasmic reticulum unfolded protein response  posttranslational protein targeting to membrane, translocation  IRE1-mediated unfolded protein response  cellular protein metabolic process  poly(A) RNA binding  renal system development  
Ontology : EGO-EBIliver development  receptor activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  cytosol  protein targeting to membrane  SRP-dependent cotranslational protein targeting to membrane  posttranslational protein targeting to membrane  nitrogen compound metabolic process  protein transporter activity  multicellular organismal aging  membrane  integral component of membrane  endoplasmic reticulum unfolded protein response  posttranslational protein targeting to membrane, translocation  IRE1-mediated unfolded protein response  cellular protein metabolic process  poly(A) RNA binding  renal system development  
Pathways : KEGGProtein export    Protein processing in endoplasmic reticulum   
Protein Interaction DatabaseSEC63
DoCM (Curated mutations)SEC63
Wikipedia pathwaysSEC63
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerSEC63 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC63
dbVarSEC63
ClinVarSEC63
1000_GenomesSEC63 
Exome Variant ServerSEC63
SNP (GeneSNP Utah)SEC63
SNP : HGBaseSEC63
Genetic variants : HAPMAPSEC63
Genomic Variants (DGV)SEC63 [DGVbeta]
Mutations
ICGC Data PortalSEC63 
TCGA Data PortalSEC63 
Tumor PortalSEC63
Somatic Mutations in Cancer : COSMICSEC63 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)6:108188960-108279482
CONAN: Copy Number AnalysisSEC63 
Mutations and Diseases : HGMDSEC63
OMIM174050    608648   
MedgenSEC63
NextProtQ9UGP8 [Medical]
GENETestsSEC63
Disease Genetic AssociationSEC63
Huge Navigator SEC63 [HugePedia]  SEC63 [HugeCancerGEM]
snp3D : Map Gene to Disease11231
DGIdb (Drug Gene Interaction db)SEC63
BioCentury BCIQSEC63
General knowledge
Homologs : HomoloGeneSEC63
Homology/Alignments : Family Browser (UCSC)SEC63
Phylogenetic Trees/Animal Genes : TreeFamSEC63
Chemical/Protein Interactions : CTD11231
Chemical/Pharm GKB GenePA134936990
Clinical trialSEC63
Cancer Resource (Charite)ENSG00000025796
Other databases
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
CoreMineSEC63
GoPubMedSEC63
iHOPSEC63
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 12:15:37 CEST 2015

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