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SELENOS (selenoprotein S)

Identity

Alias_namesVIMP
VCP-interacting membrane protein
VCP interacting membrane selenoprotein
Alias_symbol (synonym)SELS
MGC2553
SBBI8
AD-015
SEPS1
Other aliasADO15
HGNC (Hugo) SELENOS
LocusID (NCBI) 55829
Atlas_Id 56471
Location 15q26.3  [Link to chromosome band 15q26]
Location_base_pair Starts at 101272182 and ends at 101277520 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SELENOS   30396
Cards
Entrez_Gene (NCBI)SELENOS  55829  selenoprotein S
AliasesAD-015; ADO15; SBBI8; SELS; 
SEPS1; VIMP
GeneCards (Weizmann)SELENOS
Ensembl hg19 (Hinxton)ENSG00000131871 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131871 [Gene_View]  chr15:101272182-101277520 [Contig_View]  SELENOS [Vega]
ICGC DataPortalENSG00000131871
TCGA cBioPortalSELENOS
AceView (NCBI)SELENOS
Genatlas (Paris)SELENOS
WikiGenes55829
SOURCE (Princeton)SELENOS
Genetics Home Reference (NIH)SELENOS
Genomic and cartography
GoldenPath hg38 (UCSC)SELENOS  -     chr15:101272182-101277520 -  15q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SELENOS  -     15q26.3   [Description]    (hg19-Feb_2009)
EnsemblSELENOS - 15q26.3 [CytoView hg19]  SELENOS - 15q26.3 [CytoView hg38]
Mapping of homologs : NCBISELENOS [Mapview hg19]  SELENOS [Mapview hg38]
OMIM607918   
Gene and transcription
Genbank (Entrez)AA487772 AF157317 AF328864 AI673590 AK026455
RefSeq transcript (Entrez)NM_018445 NM_203472
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SELENOS
Cluster EST : UnigeneHs.32148 [ NCBI ]
CGAP (NCI)Hs.32148
Alternative Splicing GalleryENSG00000131871
Gene ExpressionSELENOS [ NCBI-GEO ]   SELENOS [ EBI - ARRAY_EXPRESS ]   SELENOS [ SEEK ]   SELENOS [ MEM ]
Gene Expression Viewer (FireBrowse)SELENOS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55829
GTEX Portal (Tissue expression)SELENOS
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BQE4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BQE4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BQE4
Splice isoforms : SwissVarQ9BQE4
PhosPhoSitePlusQ9BQE4
Domains : Interpro (EBI)Selenoprotein_S   
Domain families : Pfam (Sanger)Selenoprotein_S (PF06936)   
Domain families : Pfam (NCBI)pfam06936   
Conserved Domain (NCBI)SELENOS
DMDM Disease mutations55829
Blocks (Seattle)SELENOS
PDB (SRS)2Q2F   
PDB (PDBSum)2Q2F   
PDB (IMB)2Q2F   
PDB (RSDB)2Q2F   
Structural Biology KnowledgeBase2Q2F   
SCOP (Structural Classification of Proteins)2Q2F   
CATH (Classification of proteins structures)2Q2F   
SuperfamilyQ9BQE4
Human Protein AtlasENSG00000131871
Peptide AtlasQ9BQE4
HPRD12133
IPIIPI00020468   IPI01015108   IPI01010559   IPI00979409   
Protein Interaction databases
DIP (DOE-UCLA)Q9BQE4
IntAct (EBI)Q9BQE4
FunCoupENSG00000131871
BioGRIDSELENOS
STRING (EMBL)SELENOS
ZODIACSELENOS
Ontologies - Pathways
QuickGOQ9BQE4
Ontology : AmiGOnegative regulation of acute inflammatory response to antigenic stimulus  receptor activity  protein binding  endoplasmic reticulum  endoplasmic reticulum  cytoplasmic microtubule  plasma membrane  regulation of gluconeogenesis  ER overload response  ER overload response  response to glucose  antioxidant activity  enzyme binding  integral component of endoplasmic reticulum membrane  ubiquitin-dependent ERAD pathway  endoplasmic reticulum unfolded protein response  retrograde protein transport, ER to cytosol  negative regulation of interleukin-6 production  negative regulation of tumor necrosis factor production  cellular response to insulin stimulus  very-low-density lipoprotein particle  low-density lipoprotein particle  cellular response to oxidative stress  Derlin-1-VIMP complex  Derlin-1 retrotranslocation complex  establishment of protein localization  cell redox homeostasis  negative regulation of glycogen biosynthetic process  negative regulation of glucose import  negative regulation of inflammatory response  ATPase binding  negative regulation of nitric-oxide synthase biosynthetic process  response to redox state  cellular response to lipopolysaccharide  regulation of nitric oxide metabolic process  cellular oxidant detoxification  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  ubiquitin-specific protease binding  negative regulation of macrophage apoptotic process  
Ontology : EGO-EBInegative regulation of acute inflammatory response to antigenic stimulus  receptor activity  protein binding  endoplasmic reticulum  endoplasmic reticulum  cytoplasmic microtubule  plasma membrane  regulation of gluconeogenesis  ER overload response  ER overload response  response to glucose  antioxidant activity  enzyme binding  integral component of endoplasmic reticulum membrane  ubiquitin-dependent ERAD pathway  endoplasmic reticulum unfolded protein response  retrograde protein transport, ER to cytosol  negative regulation of interleukin-6 production  negative regulation of tumor necrosis factor production  cellular response to insulin stimulus  very-low-density lipoprotein particle  low-density lipoprotein particle  cellular response to oxidative stress  Derlin-1-VIMP complex  Derlin-1 retrotranslocation complex  establishment of protein localization  cell redox homeostasis  negative regulation of glycogen biosynthetic process  negative regulation of glucose import  negative regulation of inflammatory response  ATPase binding  negative regulation of nitric-oxide synthase biosynthetic process  response to redox state  cellular response to lipopolysaccharide  regulation of nitric oxide metabolic process  cellular oxidant detoxification  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  ubiquitin-specific protease binding  negative regulation of macrophage apoptotic process  
NDEx NetworkSELENOS
Atlas of Cancer Signalling NetworkSELENOS
Wikipedia pathwaysSELENOS
Orthology - Evolution
OrthoDB55829
GeneTree (enSembl)ENSG00000131871
Phylogenetic Trees/Animal Genes : TreeFamSELENOS
HOVERGENQ9BQE4
HOGENOMQ9BQE4
Homologs : HomoloGeneSELENOS
Homology/Alignments : Family Browser (UCSC)SELENOS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSELENOS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SELENOS
dbVarSELENOS
ClinVarSELENOS
1000_GenomesSELENOS 
Exome Variant ServerSELENOS
ExAC (Exome Aggregation Consortium)SELENOS (select the gene name)
Genetic variants : HAPMAP55829
Genomic Variants (DGV)SELENOS [DGVbeta]
DECIPHERSELENOS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSELENOS 
Mutations
ICGC Data PortalSELENOS 
TCGA Data PortalSELENOS 
Broad Tumor PortalSELENOS
OASIS PortalSELENOS [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSELENOS
BioMutasearch SELENOS
DgiDB (Drug Gene Interaction Database)SELENOS
DoCM (Curated mutations)SELENOS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SELENOS (select a term)
intoGenSELENOS
Cancer3DSELENOS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607918   
Orphanet
MedgenSELENOS
Genetic Testing Registry SELENOS
NextProtQ9BQE4 [Medical]
TSGene55829
GENETestsSELENOS
Target ValidationSELENOS
Huge Navigator SELENOS [HugePedia]
snp3D : Map Gene to Disease55829
BioCentury BCIQSELENOS
ClinGenSELENOS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55829
Chemical/Pharm GKB GenePA166048999
Clinical trialSELENOS
Miscellaneous
canSAR (ICR)SELENOS (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSELENOS
EVEXSELENOS
GoPubMedSELENOS
iHOPSELENOS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:30:23 CEST 2017

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