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SELP (selectin P)

Identity

Alias_namesGRMP
selectin P (granule membrane protein 140kD, antigen CD62)
selectin P (granule membrane protein 140kDa, antigen CD62)
Alias_symbol (synonym)CD62
PSEL
PADGEM
GMP140
CD62P
Other aliasLECAM3
HGNC (Hugo) SELP
LocusID (NCBI) 6403
Atlas_Id 42250
Location 1q24.2  [Link to chromosome band 1q24]
Location_base_pair Starts at 169588850 and ends at 169630139 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SELP   10721
Cards
Entrez_Gene (NCBI)SELP  6403  selectin P
AliasesCD62; CD62P; GMP140; GRMP; 
LECAM3; PADGEM; PSEL
GeneCards (Weizmann)SELP
Ensembl hg19 (Hinxton)ENSG00000174175 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174175 [Gene_View]  chr1:169588850-169630139 [Contig_View]  SELP [Vega]
ICGC DataPortalENSG00000174175
TCGA cBioPortalSELP
AceView (NCBI)SELP
Genatlas (Paris)SELP
WikiGenes6403
SOURCE (Princeton)SELP
Genetics Home Reference (NIH)SELP
Genomic and cartography
GoldenPath hg38 (UCSC)SELP  -     chr1:169588850-169630139 -  1q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SELP  -     1q24.2   [Description]    (hg19-Feb_2009)
EnsemblSELP - 1q24.2 [CytoView hg19]  SELP - 1q24.2 [CytoView hg38]
Mapping of homologs : NCBISELP [Mapview hg19]  SELP [Mapview hg38]
OMIM147050   173610   
Gene and transcription
Genbank (Entrez)AK312884 AY367063 BC028067 BC068533 DA926598
RefSeq transcript (Entrez)NM_003005
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SELP
Cluster EST : UnigeneHs.73800 [ NCBI ]
CGAP (NCI)Hs.73800
Alternative Splicing GalleryENSG00000174175
Gene ExpressionSELP [ NCBI-GEO ]   SELP [ EBI - ARRAY_EXPRESS ]   SELP [ SEEK ]   SELP [ MEM ]
Gene Expression Viewer (FireBrowse)SELP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6403
GTEX Portal (Tissue expression)SELP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16109   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16109  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16109
Splice isoforms : SwissVarP16109
PhosPhoSitePlusP16109
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    SUSHI (PS50923)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    C-type_lectin_CS    CTDL_fold    EGF-like_CS    EGF-like_dom    Selectin_CTLD    Selectin_superfamily    Sushi_SCR_CCP_dom   
Domain families : Pfam (Sanger)Lectin_C (PF00059)    Sushi (PF00084)   
Domain families : Pfam (NCBI)pfam00059    pfam00084   
Domain families : Smart (EMBL)CCP (SM00032)  CLECT (SM00034)  
Conserved Domain (NCBI)SELP
DMDM Disease mutations6403
Blocks (Seattle)SELP
PDB (SRS)1FSB    1G1Q    1G1R    1G1S    1HES    1KJD   
PDB (PDBSum)1FSB    1G1Q    1G1R    1G1S    1HES    1KJD   
PDB (IMB)1FSB    1G1Q    1G1R    1G1S    1HES    1KJD   
PDB (RSDB)1FSB    1G1Q    1G1R    1G1S    1HES    1KJD   
Structural Biology KnowledgeBase1FSB    1G1Q    1G1R    1G1S    1HES    1KJD   
SCOP (Structural Classification of Proteins)1FSB    1G1Q    1G1R    1G1S    1HES    1KJD   
CATH (Classification of proteins structures)1FSB    1G1Q    1G1R    1G1S    1HES    1KJD   
SuperfamilyP16109
Human Protein AtlasENSG00000174175
Peptide AtlasP16109
HPRD01433
IPIIPI00295339   IPI00643835   IPI00645234   IPI00514796   IPI00644144   IPI00514233   IPI00646956   IPI00640405   
Protein Interaction databases
DIP (DOE-UCLA)P16109
IntAct (EBI)P16109
FunCoupENSG00000174175
BioGRIDSELP
STRING (EMBL)SELP
ZODIACSELP
Ontologies - Pathways
QuickGOP16109
Ontology : AmiGOlipopolysaccharide binding  glycoprotein binding  platelet degranulation  positive regulation of leukocyte migration  protein binding  extracellular space  plasma membrane  integral component of plasma membrane  inflammatory response  cell adhesion  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  leukocyte cell-cell adhesion  heparin binding  external side of plasma membrane  positive regulation of platelet activation  positive regulation of phosphatidylinositol 3-kinase signaling  platelet dense granule membrane  platelet alpha granule membrane  platelet alpha granule membrane  response to lipopolysaccharide  regulation of integrin activation  sialic acid binding  calcium-mediated signaling using intracellular calcium source  fucose binding  glycosphingolipid binding  calcium-dependent protein binding  defense response to Gram-negative bacterium  leukocyte migration  leukocyte tethering or rolling  oligosaccharide binding  
Ontology : EGO-EBIlipopolysaccharide binding  glycoprotein binding  platelet degranulation  positive regulation of leukocyte migration  protein binding  extracellular space  plasma membrane  integral component of plasma membrane  inflammatory response  cell adhesion  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  leukocyte cell-cell adhesion  heparin binding  external side of plasma membrane  positive regulation of platelet activation  positive regulation of phosphatidylinositol 3-kinase signaling  platelet dense granule membrane  platelet alpha granule membrane  platelet alpha granule membrane  response to lipopolysaccharide  regulation of integrin activation  sialic acid binding  calcium-mediated signaling using intracellular calcium source  fucose binding  glycosphingolipid binding  calcium-dependent protein binding  defense response to Gram-negative bacterium  leukocyte migration  leukocyte tethering or rolling  oligosaccharide binding  
Pathways : BIOCARTACells and Molecules involved in local acute inflammatory response [Genes]    Eph Kinases and ephrins support platelet aggregation [Genes]    Adhesion and Diapedesis of Granulocytes [Genes]    Monocyte and its Surface Molecules [Genes]   
Pathways : KEGGCell adhesion molecules (CAMs)    Malaria    Staphylococcus aureus infection   
NDEx NetworkSELP
Atlas of Cancer Signalling NetworkSELP
Wikipedia pathwaysSELP
Orthology - Evolution
OrthoDB6403
GeneTree (enSembl)ENSG00000174175
Phylogenetic Trees/Animal Genes : TreeFamSELP
HOVERGENP16109
HOGENOMP16109
Homologs : HomoloGeneSELP
Homology/Alignments : Family Browser (UCSC)SELP
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSELP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SELP
dbVarSELP
ClinVarSELP
1000_GenomesSELP 
Exome Variant ServerSELP
ExAC (Exome Aggregation Consortium)SELP (select the gene name)
Genetic variants : HAPMAP6403
Genomic Variants (DGV)SELP [DGVbeta]
DECIPHERSELP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSELP 
Mutations
ICGC Data PortalSELP 
TCGA Data PortalSELP 
Broad Tumor PortalSELP
OASIS PortalSELP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSELP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSELP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SELP
DgiDB (Drug Gene Interaction Database)SELP
DoCM (Curated mutations)SELP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SELP (select a term)
intoGenSELP
Cancer3DSELP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147050    173610   
Orphanet
MedgenSELP
Genetic Testing Registry SELP
NextProtP16109 [Medical]
TSGene6403
GENETestsSELP
Target ValidationSELP
Huge Navigator SELP [HugePedia]
snp3D : Map Gene to Disease6403
BioCentury BCIQSELP
ClinGenSELP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6403
Chemical/Pharm GKB GenePA35643
Clinical trialSELP
Miscellaneous
canSAR (ICR)SELP (select the gene name)
Probes
Litterature
PubMed370 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSELP
EVEXSELP
GoPubMedSELP
iHOPSELP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:14:00 CEST 2017

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