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SEMA3A (semaphorin 3A)

Identity

Alias_namesSEMAD
sema domain
Alias_symbol (synonym)SEMA1
SemD
coll-1
Hsema-I
Other aliasCOLL1
HH16
Hsema-III
SEMAIII
SEMAL
HGNC (Hugo) SEMA3A
LocusID (NCBI) 10371
Atlas_Id 43720
Location 7q21.11  [Link to chromosome band 7q21]
Location_base_pair Starts at 83958343 and ends at 84194901 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALG11 (13q14.3) / SEMA3A (7q21.11)SEMA3A (7q21.11) / ARFGEF2 (20q13.13)SEMA3A (7q21.11) / USP47 (11p15.3)
WBSCR22 (7q11.23) / SEMA3A (7q21.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEMA3A   10723
Cards
Entrez_Gene (NCBI)SEMA3A  10371  semaphorin 3A
AliasesCOLL1; HH16; Hsema-I; Hsema-III; 
SEMA1; SEMAD; SEMAIII; SEMAL; SemD; coll-1
GeneCards (Weizmann)SEMA3A
Ensembl hg19 (Hinxton)ENSG00000075213 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000075213 [Gene_View]  chr7:83958343-84194901 [Contig_View]  SEMA3A [Vega]
ICGC DataPortalENSG00000075213
TCGA cBioPortalSEMA3A
AceView (NCBI)SEMA3A
Genatlas (Paris)SEMA3A
WikiGenes10371
SOURCE (Princeton)SEMA3A
Genetics Home Reference (NIH)SEMA3A
Genomic and cartography
GoldenPath hg38 (UCSC)SEMA3A  -     chr7:83958343-84194901 -  7q21.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEMA3A  -     7q21.11   [Description]    (hg19-Feb_2009)
EnsemblSEMA3A - 7q21.11 [CytoView hg19]  SEMA3A - 7q21.11 [CytoView hg38]
Mapping of homologs : NCBISEMA3A [Mapview hg19]  SEMA3A [Mapview hg38]
OMIM603961   614897   
Gene and transcription
Genbank (Entrez)AK289954 BC111416 BM723807 BU186364 BX491494
RefSeq transcript (Entrez)NM_006080
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEMA3A
Cluster EST : UnigeneHs.252451 [ NCBI ]
CGAP (NCI)Hs.252451
Alternative Splicing GalleryENSG00000075213
Gene ExpressionSEMA3A [ NCBI-GEO ]   SEMA3A [ EBI - ARRAY_EXPRESS ]   SEMA3A [ SEEK ]   SEMA3A [ MEM ]
Gene Expression Viewer (FireBrowse)SEMA3A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10371
GTEX Portal (Tissue expression)SEMA3A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14563   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14563  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14563
Splice isoforms : SwissVarQ14563
PhosPhoSitePlusQ14563
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    SEMA (PS51004)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    PSI    Semap_dom    Semaphorin    WD40/YVTN_repeat-like_dom   
Domain families : Pfam (Sanger)Sema (PF01403)   
Domain families : Pfam (NCBI)pfam01403   
Domain families : Smart (EMBL)IG (SM00409)  PSI (SM00423)  Sema (SM00630)  
Conserved Domain (NCBI)SEMA3A
DMDM Disease mutations10371
Blocks (Seattle)SEMA3A
SuperfamilyQ14563
Human Protein AtlasENSG00000075213
Peptide AtlasQ14563
HPRD04908
IPIIPI00031510   IPI00927557   IPI00927320   IPI00926966   
Protein Interaction databases
DIP (DOE-UCLA)Q14563
IntAct (EBI)Q14563
FunCoupENSG00000075213
BioGRIDSEMA3A
STRING (EMBL)SEMA3A
ZODIACSEMA3A
Ontologies - Pathways
QuickGOQ14563
Ontology : AmiGOneuron migration  regulation of heart rate  extracellular region  extracellular space  apoptotic process  axon guidance  axonal fasciculation  negative regulation of epithelial cell migration  negative regulation of neuron projection development  facial nerve structural organization  trigeminal nerve structural organization  nerve development  olfactory bulb development  branchiomotor neuron axon guidance  gonadotrophin-releasing hormone neuronal migration to the hypothalamus  semaphorin receptor binding  axon  dendrite  ventral trunk neural crest cell migration  neuropilin binding  chemorepellent activity  sympathetic nervous system development  dendrite morphogenesis  regulation of axon extension involved in axon guidance  negative regulation of axon extension involved in axon guidance  axon extension involved in axon guidance  sensory system development  negative chemotaxis  axonogenesis involved in innervation  dichotomous subdivision of terminal units involved in salivary gland branching  sympathetic ganglion development  trigeminal ganglion development  semaphorin-plexin signaling pathway  sympathetic neuron projection extension  sympathetic neuron projection guidance  neural crest cell migration involved in autonomic nervous system development  semaphorin-plexin signaling pathway involved in neuron projection guidance  semaphorin-plexin signaling pathway involved in axon guidance  neural crest cell migration involved in sympathetic nervous system development  facioacoustic ganglion development  positive regulation of male gonad development  positive regulation of neuron migration  
Ontology : EGO-EBIneuron migration  regulation of heart rate  extracellular region  extracellular space  apoptotic process  axon guidance  axonal fasciculation  negative regulation of epithelial cell migration  negative regulation of neuron projection development  facial nerve structural organization  trigeminal nerve structural organization  nerve development  olfactory bulb development  branchiomotor neuron axon guidance  gonadotrophin-releasing hormone neuronal migration to the hypothalamus  semaphorin receptor binding  axon  dendrite  ventral trunk neural crest cell migration  neuropilin binding  chemorepellent activity  sympathetic nervous system development  dendrite morphogenesis  regulation of axon extension involved in axon guidance  negative regulation of axon extension involved in axon guidance  axon extension involved in axon guidance  sensory system development  negative chemotaxis  axonogenesis involved in innervation  dichotomous subdivision of terminal units involved in salivary gland branching  sympathetic ganglion development  trigeminal ganglion development  semaphorin-plexin signaling pathway  sympathetic neuron projection extension  sympathetic neuron projection guidance  neural crest cell migration involved in autonomic nervous system development  semaphorin-plexin signaling pathway involved in neuron projection guidance  semaphorin-plexin signaling pathway involved in axon guidance  neural crest cell migration involved in sympathetic nervous system development  facioacoustic ganglion development  positive regulation of male gonad development  positive regulation of neuron migration  
Pathways : KEGGAxon guidance   
NDEx NetworkSEMA3A
Atlas of Cancer Signalling NetworkSEMA3A
Wikipedia pathwaysSEMA3A
Orthology - Evolution
OrthoDB10371
GeneTree (enSembl)ENSG00000075213
Phylogenetic Trees/Animal Genes : TreeFamSEMA3A
HOVERGENQ14563
HOGENOMQ14563
Homologs : HomoloGeneSEMA3A
Homology/Alignments : Family Browser (UCSC)SEMA3A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEMA3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEMA3A
dbVarSEMA3A
ClinVarSEMA3A
1000_GenomesSEMA3A 
Exome Variant ServerSEMA3A
ExAC (Exome Aggregation Consortium)SEMA3A (select the gene name)
Genetic variants : HAPMAP10371
Genomic Variants (DGV)SEMA3A [DGVbeta]
DECIPHERSEMA3A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEMA3A 
Mutations
ICGC Data PortalSEMA3A 
TCGA Data PortalSEMA3A 
Broad Tumor PortalSEMA3A
OASIS PortalSEMA3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEMA3A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEMA3A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEMA3A
DgiDB (Drug Gene Interaction Database)SEMA3A
DoCM (Curated mutations)SEMA3A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEMA3A (select a term)
intoGenSEMA3A
Cancer3DSEMA3A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603961    614897   
Orphanet3249   
MedgenSEMA3A
Genetic Testing Registry SEMA3A
NextProtQ14563 [Medical]
TSGene10371
GENETestsSEMA3A
Target ValidationSEMA3A
Huge Navigator SEMA3A [HugePedia]
snp3D : Map Gene to Disease10371
BioCentury BCIQSEMA3A
ClinGenSEMA3A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10371
Chemical/Pharm GKB GenePA35645
Clinical trialSEMA3A
Miscellaneous
canSAR (ICR)SEMA3A (select the gene name)
Probes
Litterature
PubMed116 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEMA3A
EVEXSEMA3A
GoPubMedSEMA3A
iHOPSEMA3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:54:49 CEST 2017

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