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SEMA4B (semaphorin 4B)

Identity

Alias_namesSEMAC
sema domain
Alias_symbol (synonym)SemC
KIAA1745
MGC131831
Other alias
HGNC (Hugo) SEMA4B
LocusID (NCBI) 10509
Atlas_Id 55219
Location 15q26.1  [Link to chromosome band 15q26]
Location_base_pair Starts at 90184920 and ends at 90229660 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CBS (21q22.3) / SEMA4B (15q26.1)SEMA4B (15q26.1) / CACNA1C (12p13.33)SEMA4B (15q26.1) / CERS3 (15q26.3)
SEMA4B (15q26.1) / SEMA4B (15q26.1)SEMA4B (15q26.1) / WDR93 (15q26.1)SEMA4B (15q26.1) / ZNF710 (15q26.1)
SEMA4B 15q26.1 / CERS3 15q26.3SEMA4B 15q26.1 / WDR93 15q26.1SEMA4B 15q26.1 / ZNF710 15q26.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEMA4B   10730
Cards
Entrez_Gene (NCBI)SEMA4B  10509  semaphorin 4B
AliasesSEMAC; SemC
GeneCards (Weizmann)SEMA4B
Ensembl hg19 (Hinxton)ENSG00000185033 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185033 [Gene_View]  chr15:90184920-90229660 [Contig_View]  SEMA4B [Vega]
ICGC DataPortalENSG00000185033
TCGA cBioPortalSEMA4B
AceView (NCBI)SEMA4B
Genatlas (Paris)SEMA4B
WikiGenes10509
SOURCE (Princeton)SEMA4B
Genetics Home Reference (NIH)SEMA4B
Genomic and cartography
GoldenPath hg38 (UCSC)SEMA4B  -     chr15:90184920-90229660 +  15q26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEMA4B  -     15q26.1   [Description]    (hg19-Feb_2009)
EnsemblSEMA4B - 15q26.1 [CytoView hg19]  SEMA4B - 15q26.1 [CytoView hg38]
Mapping of homologs : NCBISEMA4B [Mapview hg19]  SEMA4B [Mapview hg38]
OMIM617029   
Gene and transcription
Genbank (Entrez)AB051532 AF258561 AK026108 AK026133 AK027083
RefSeq transcript (Entrez)NM_001324029 NM_001324030 NM_001324031 NM_001324032 NM_001324033 NM_001324034 NM_020210 NM_198925
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEMA4B
Cluster EST : UnigeneHs.474935 [ NCBI ]
CGAP (NCI)Hs.474935
Alternative Splicing GalleryENSG00000185033
Gene ExpressionSEMA4B [ NCBI-GEO ]   SEMA4B [ EBI - ARRAY_EXPRESS ]   SEMA4B [ SEEK ]   SEMA4B [ MEM ]
Gene Expression Viewer (FireBrowse)SEMA4B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10509
GTEX Portal (Tissue expression)SEMA4B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPR2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPR2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPR2
Splice isoforms : SwissVarQ9NPR2
PhosPhoSitePlusQ9NPR2
Domaine pattern : Prosite (Expaxy)SEMA (PS51004)   
Domains : Interpro (EBI)Plexin_repeat    PSI    Semap_dom    Semaphorin    WD40/YVTN_repeat-like_dom   
Domain families : Pfam (Sanger)PSI (PF01437)    Sema (PF01403)   
Domain families : Pfam (NCBI)pfam01437    pfam01403   
Domain families : Smart (EMBL)PSI (SM00423)  Sema (SM00630)  
Conserved Domain (NCBI)SEMA4B
DMDM Disease mutations10509
Blocks (Seattle)SEMA4B
SuperfamilyQ9NPR2
Human Protein AtlasENSG00000185033
Peptide AtlasQ9NPR2
HPRD10217
IPIIPI00513964   IPI00383183   IPI00419724   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPR2
IntAct (EBI)Q9NPR2
FunCoupENSG00000185033
BioGRIDSEMA4B
STRING (EMBL)SEMA4B
ZODIACSEMA4B
Ontologies - Pathways
QuickGOQ9NPR2
Ontology : AmiGOnervous system development  integral component of membrane  cell differentiation  
Ontology : EGO-EBInervous system development  integral component of membrane  cell differentiation  
Pathways : KEGGAxon guidance   
NDEx NetworkSEMA4B
Atlas of Cancer Signalling NetworkSEMA4B
Wikipedia pathwaysSEMA4B
Orthology - Evolution
OrthoDB10509
GeneTree (enSembl)ENSG00000185033
Phylogenetic Trees/Animal Genes : TreeFamSEMA4B
HOVERGENQ9NPR2
HOGENOMQ9NPR2
Homologs : HomoloGeneSEMA4B
Homology/Alignments : Family Browser (UCSC)SEMA4B
Gene fusions - Rearrangements
Fusion : MitelmanSEMA4B/CERS3 [15q26.1/15q26.3]  
Fusion : MitelmanSEMA4B/WDR93 [15q26.1/15q26.1]  [t(15;15)(q26;q26)]  
Fusion : MitelmanSEMA4B/ZNF710 [15q26.1/15q26.1]  [t(15;15)(q26;q26)]  
Fusion: TCGASEMA4B 15q26.1 CERS3 15q26.3 LUAD
Fusion: TCGASEMA4B 15q26.1 WDR93 15q26.1 KIRC
Fusion: TCGASEMA4B 15q26.1 ZNF710 15q26.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEMA4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEMA4B
dbVarSEMA4B
ClinVarSEMA4B
1000_GenomesSEMA4B 
Exome Variant ServerSEMA4B
ExAC (Exome Aggregation Consortium)SEMA4B (select the gene name)
Genetic variants : HAPMAP10509
Genomic Variants (DGV)SEMA4B [DGVbeta]
DECIPHERSEMA4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEMA4B 
Mutations
ICGC Data PortalSEMA4B 
TCGA Data PortalSEMA4B 
Broad Tumor PortalSEMA4B
OASIS PortalSEMA4B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEMA4B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEMA4B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEMA4B
DgiDB (Drug Gene Interaction Database)SEMA4B
DoCM (Curated mutations)SEMA4B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEMA4B (select a term)
intoGenSEMA4B
Cancer3DSEMA4B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617029   
Orphanet
MedgenSEMA4B
Genetic Testing Registry SEMA4B
NextProtQ9NPR2 [Medical]
TSGene10509
GENETestsSEMA4B
Target ValidationSEMA4B
Huge Navigator SEMA4B [HugePedia]
snp3D : Map Gene to Disease10509
BioCentury BCIQSEMA4B
ClinGenSEMA4B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10509
Chemical/Pharm GKB GenePA35652
Clinical trialSEMA4B
Miscellaneous
canSAR (ICR)SEMA4B (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEMA4B
EVEXSEMA4B
GoPubMedSEMA4B
iHOPSEMA4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:30:25 CEST 2017

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