SEMA4B (semaphorin 4B)

2015-05-01  

Identity

HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
SEMAC,SemC
FUSION GENES

Other Information

Locus ID:

NCBI: 10509
MIM: 617029
HGNC: 10730
Ensembl: ENSG00000185033

Variants:

dbSNP: 10509
ClinVar: 10509
TCGA: ENSG00000185033
COSMIC: SEMA4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185033ENST00000332496Q9NPR2
ENSG00000185033ENST00000411539Q9NPR2
ENSG00000185033ENST00000558895H0YMR1
ENSG00000185033ENST00000559074H0YMZ3
ENSG00000185033ENST00000559247H0YNM2
ENSG00000185033ENST00000559300H0YKV7
ENSG00000185033ENST00000559322H0YLN3
ENSG00000185033ENST00000559792H0YMD6
ENSG00000185033ENST00000559983H0YN49
ENSG00000185033ENST00000560089H0YM68
ENSG00000185033ENST00000561085H0YNC4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
250959812014SEMA4b inhibits MMP9 to prevent metastasis of non-small cell lung cancer.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
257463852015SEMA4B inhibits growth of non-small cell lung cancer in vitro and in vivo.11
244742522014Hypoxia and hypoxia-inducible factor 1 repress SEMA4B expression to promote non-small cell lung cancer invasion.4

Citation

Dessen P

SEMA4B (semaphorin 4B)

Atlas Genet Cytogenet Oncol Haematol. 2015-05-01

Online version: http://atlasgeneticsoncology.org/gene/55219/sema4b