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SEMA5B (semaphorin 5B)

Identity

Alias_namesSEMAG
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Alias_symbol (synonym)SemG
KIAA1445
FLJ10372
Other alias
HGNC (Hugo) SEMA5B
LocusID (NCBI) 54437
Atlas_Id 73111
Location 3q21.1  [Link to chromosome band 3q21]
Location_base_pair Starts at 122909193 and ends at 123027812 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RAB3IP (12q15) / SEMA5B (3q21.1)ROBO1 (3p12.3) / SEMA5B (3q21.1)SEMA5B (3q21.1) / LOC100130557 ()
SPACA6 (19q13.41) / SEMA5B (3q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEMA5B   10737
Cards
Entrez_Gene (NCBI)SEMA5B  54437  semaphorin 5B
AliasesSEMAG; SemG
GeneCards (Weizmann)SEMA5B
Ensembl hg19 (Hinxton)ENSG00000082684 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000082684 [Gene_View]  chr3:122909193-123027812 [Contig_View]  SEMA5B [Vega]
ICGC DataPortalENSG00000082684
TCGA cBioPortalSEMA5B
AceView (NCBI)SEMA5B
Genatlas (Paris)SEMA5B
WikiGenes54437
SOURCE (Princeton)SEMA5B
Genetics Home Reference (NIH)SEMA5B
Genomic and cartography
GoldenPath hg38 (UCSC)SEMA5B  -     chr3:122909193-123027812 -  3q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEMA5B  -     3q21.1   [Description]    (hg19-Feb_2009)
EnsemblSEMA5B - 3q21.1 [CytoView hg19]  SEMA5B - 3q21.1 [CytoView hg38]
Mapping of homologs : NCBISEMA5B [Mapview hg19]  SEMA5B [Mapview hg38]
OMIM609298   
Gene and transcription
Genbank (Entrez)AB040878 AK001234 AK091481 AK291407 AK294528
RefSeq transcript (Entrez)NM_001031702 NM_001256346 NM_001256347 NM_001256348 NM_018987
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEMA5B
Cluster EST : UnigeneHs.210870 [ NCBI ]
CGAP (NCI)Hs.210870
Alternative Splicing GalleryENSG00000082684
Gene ExpressionSEMA5B [ NCBI-GEO ]   SEMA5B [ EBI - ARRAY_EXPRESS ]   SEMA5B [ SEEK ]   SEMA5B [ MEM ]
Gene Expression Viewer (FireBrowse)SEMA5B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54437
GTEX Portal (Tissue expression)SEMA5B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P283   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P283  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P283
Splice isoforms : SwissVarQ9P283
PhosPhoSitePlusQ9P283
Domaine pattern : Prosite (Expaxy)SEMA (PS51004)    TSP1 (PS50092)   
Domains : Interpro (EBI)Plexin_repeat    PSI    Semap_dom    Semaphorin    TSP1_rpt    WD40/YVTN_repeat-like_dom   
Domain families : Pfam (Sanger)PSI (PF01437)    Sema (PF01403)    TSP_1 (PF00090)   
Domain families : Pfam (NCBI)pfam01437    pfam01403    pfam00090   
Domain families : Smart (EMBL)PSI (SM00423)  Sema (SM00630)  TSP1 (SM00209)  
Conserved Domain (NCBI)SEMA5B
DMDM Disease mutations54437
Blocks (Seattle)SEMA5B
SuperfamilyQ9P283
Human Protein AtlasENSG00000082684
Peptide AtlasQ9P283
HPRD15322
IPIIPI01011436   IPI00788999   IPI01018914   IPI00395376   IPI00790894   IPI00420099   IPI00790371   IPI00945133   
Protein Interaction databases
DIP (DOE-UCLA)Q9P283
IntAct (EBI)Q9P283
FunCoupENSG00000082684
BioGRIDSEMA5B
STRING (EMBL)SEMA5B
ZODIACSEMA5B
Ontologies - Pathways
QuickGOQ9P283
Ontology : AmiGOintegral component of membrane  axon extension  detection of light stimulus involved in visual perception  neuron projection guidance  
Ontology : EGO-EBIintegral component of membrane  axon extension  detection of light stimulus involved in visual perception  neuron projection guidance  
Pathways : KEGGAxon guidance   
NDEx NetworkSEMA5B
Atlas of Cancer Signalling NetworkSEMA5B
Wikipedia pathwaysSEMA5B
Orthology - Evolution
OrthoDB54437
GeneTree (enSembl)ENSG00000082684
Phylogenetic Trees/Animal Genes : TreeFamSEMA5B
HOVERGENQ9P283
HOGENOMQ9P283
Homologs : HomoloGeneSEMA5B
Homology/Alignments : Family Browser (UCSC)SEMA5B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEMA5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEMA5B
dbVarSEMA5B
ClinVarSEMA5B
1000_GenomesSEMA5B 
Exome Variant ServerSEMA5B
ExAC (Exome Aggregation Consortium)SEMA5B (select the gene name)
Genetic variants : HAPMAP54437
Genomic Variants (DGV)SEMA5B [DGVbeta]
DECIPHERSEMA5B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEMA5B 
Mutations
ICGC Data PortalSEMA5B 
TCGA Data PortalSEMA5B 
Broad Tumor PortalSEMA5B
OASIS PortalSEMA5B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEMA5B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEMA5B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEMA5B
DgiDB (Drug Gene Interaction Database)SEMA5B
DoCM (Curated mutations)SEMA5B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEMA5B (select a term)
intoGenSEMA5B
Cancer3DSEMA5B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609298   
Orphanet
MedgenSEMA5B
Genetic Testing Registry SEMA5B
NextProtQ9P283 [Medical]
TSGene54437
GENETestsSEMA5B
Target ValidationSEMA5B
Huge Navigator SEMA5B [HugePedia]
snp3D : Map Gene to Disease54437
BioCentury BCIQSEMA5B
ClinGenSEMA5B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54437
Chemical/Pharm GKB GenePA35659
Clinical trialSEMA5B
Miscellaneous
canSAR (ICR)SEMA5B (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEMA5B
EVEXSEMA5B
GoPubMedSEMA5B
iHOPSEMA5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:40:21 CEST 2017

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