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SEMA6D (semaphorin 6D)

Identity

Alias_namessema domain
Alias_symbol (synonym)KIAA1479
FLJ11598
HGNC (Hugo) SEMA6D
LocusID (NCBI) 80031
Atlas_Id 50970
Location 15q21.1  [Link to chromosome band 15q21]
Location_base_pair Starts at 47476403 and ends at 48066420 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HPCAL1 (2p25.1) / SEMA6D (15q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEMA6D   16770
Cards
Entrez_Gene (NCBI)SEMA6D  80031  semaphorin 6D
Aliases
GeneCards (Weizmann)SEMA6D
Ensembl hg19 (Hinxton)ENSG00000137872 [Gene_View]  chr15:47476403-48066420 [Contig_View]  SEMA6D [Vega]
Ensembl hg38 (Hinxton)ENSG00000137872 [Gene_View]  chr15:47476403-48066420 [Contig_View]  SEMA6D [Vega]
ICGC DataPortalENSG00000137872
TCGA cBioPortalSEMA6D
AceView (NCBI)SEMA6D
Genatlas (Paris)SEMA6D
WikiGenes80031
SOURCE (Princeton)SEMA6D
Genetics Home Reference (NIH)SEMA6D
Genomic and cartography
GoldenPath hg19 (UCSC)SEMA6D  -     chr15:47476403-48066420 +  15q21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SEMA6D  -     15q21.1   [Description]    (hg38-Dec_2013)
EnsemblSEMA6D - 15q21.1 [CytoView hg19]  SEMA6D - 15q21.1 [CytoView hg38]
Mapping of homologs : NCBISEMA6D [Mapview hg19]  SEMA6D [Mapview hg38]
OMIM609295   
Gene and transcription
Genbank (Entrez)AB040912 AF389426 AF389427 AF389428 AF389429
RefSeq transcript (Entrez)NM_001198999 NM_020858 NM_024966 NM_153616 NM_153617 NM_153618 NM_153619
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_029119 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)SEMA6D
Cluster EST : UnigeneHs.511265 [ NCBI ]
CGAP (NCI)Hs.511265
Alternative Splicing GalleryENSG00000137872
Gene ExpressionSEMA6D [ NCBI-GEO ]   SEMA6D [ EBI - ARRAY_EXPRESS ]   SEMA6D [ SEEK ]   SEMA6D [ MEM ]
Gene Expression Viewer (FireBrowse)SEMA6D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80031
GTEX Portal (Tissue expression)SEMA6D
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFY4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFY4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFY4
Splice isoforms : SwissVarQ8NFY4
PhosPhoSitePlusQ8NFY4
Domaine pattern : Prosite (Expaxy)SEMA (PS51004)   
Domains : Interpro (EBI)Plexin-like_fold    Plexin_repeat    Semap_dom    Semaphorin    WD40/YVTN_repeat-like_dom   
Domain families : Pfam (Sanger)PSI (PF01437)    Sema (PF01403)   
Domain families : Pfam (NCBI)pfam01437    pfam01403   
Domain families : Smart (EMBL)PSI (SM00423)  Sema (SM00630)  
Conserved Domain (NCBI)SEMA6D
DMDM Disease mutations80031
Blocks (Seattle)SEMA6D
SuperfamilyQ8NFY4
Human Protein AtlasENSG00000137872
Peptide AtlasQ8NFY4
HPRD10221
IPIIPI00178302   IPI00332846   IPI00170551   IPI00465042   IPI00657834   IPI00374169   IPI00170617   IPI00783744   
Protein Interaction databases
DIP (DOE-UCLA)Q8NFY4
IntAct (EBI)Q8NFY4
FunCoupENSG00000137872
BioGRIDSEMA6D
STRING (EMBL)SEMA6D
ZODIACSEMA6D
Ontologies - Pathways
QuickGOQ8NFY4
Ontology : AmiGOneural crest cell migration  cytoplasm  plasma membrane  integral component of plasma membrane  positive regulation of smooth muscle cell migration  negative regulation of smooth muscle cell migration  ventricular system development  semaphorin receptor binding  positive regulation of cell migration  chemorepellent activity  negative regulation of axon extension involved in axon guidance  negative chemotaxis  semaphorin-plexin signaling pathway  
Ontology : EGO-EBIneural crest cell migration  cytoplasm  plasma membrane  integral component of plasma membrane  positive regulation of smooth muscle cell migration  negative regulation of smooth muscle cell migration  ventricular system development  semaphorin receptor binding  positive regulation of cell migration  chemorepellent activity  negative regulation of axon extension involved in axon guidance  negative chemotaxis  semaphorin-plexin signaling pathway  
Pathways : KEGGAxon guidance   
NDEx NetworkSEMA6D
Atlas of Cancer Signalling NetworkSEMA6D
Wikipedia pathwaysSEMA6D
Orthology - Evolution
OrthoDB80031
GeneTree (enSembl)ENSG00000137872
Phylogenetic Trees/Animal Genes : TreeFamSEMA6D
HOVERGENQ8NFY4
HOGENOMQ8NFY4
Homologs : HomoloGeneSEMA6D
Homology/Alignments : Family Browser (UCSC)SEMA6D
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEMA6D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEMA6D
dbVarSEMA6D
ClinVarSEMA6D
1000_GenomesSEMA6D 
Exome Variant ServerSEMA6D
ExAC (Exome Aggregation Consortium)SEMA6D (select the gene name)
Genetic variants : HAPMAP80031
Genomic Variants (DGV)SEMA6D [DGVbeta]
DECIPHER (Syndromes)15:47476403-48066420  ENSG00000137872
CONAN: Copy Number AnalysisSEMA6D 
Mutations
ICGC Data PortalSEMA6D 
TCGA Data PortalSEMA6D 
Broad Tumor PortalSEMA6D
OASIS PortalSEMA6D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEMA6D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEMA6D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEMA6D
DgiDB (Drug Gene Interaction Database)SEMA6D
DoCM (Curated mutations)SEMA6D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEMA6D (select a term)
intoGenSEMA6D
Cancer3DSEMA6D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609295   
Orphanet
MedgenSEMA6D
Genetic Testing Registry SEMA6D
NextProtQ8NFY4 [Medical]
TSGene80031
GENETestsSEMA6D
Huge Navigator SEMA6D [HugePedia]
snp3D : Map Gene to Disease80031
BioCentury BCIQSEMA6D
ClinGenSEMA6D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80031
Chemical/Pharm GKB GenePA134951035
Clinical trialSEMA6D
Miscellaneous
canSAR (ICR)SEMA6D (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEMA6D
EVEXSEMA6D
GoPubMedSEMA6D
iHOPSEMA6D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:50:56 CET 2016

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