Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SENP5 (SUMO1/sentrin specific peptidase 5)

Identity

Alias_namesSUMO1/sentrin specific protease 5
Alias_symbol (synonym)MGC27076
Other alias-
HGNC (Hugo) SENP5
LocusID (NCBI)
Atlas_Id 50626
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 196867856 and ends at 196934713 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BSCL2 (11q12.3) / SENP5 (3q29)EHHADH (3q27.2) / SENP5 (3q29)SENP5 (3q29) / PALMD (1p21.2)
SENP5 (3q29) / PIGZ (3q29)SENP5 (3q29) / STAMBPL1 (10q23.31)SENP5 (3q29) / TCTEX1D2 (3q29)
SENP5 3q29 / PIGZ 3q29SENP5 3q29 / TCTEX1D2 3q29

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)SENP5   28407
Cards
Entrez_Gene (NCBI)SENP5  205564  SUMO1/sentrin specific peptidase 5
Aliases
GeneCards (Weizmann)SENP5
Ensembl hg19 (Hinxton)ENSG00000119231 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119231 [Gene_View]  chr3:196867856-196934713 [Contig_View]  SENP5 [Vega]
ICGC DataPortalENSG00000119231
TCGA cBioPortalSENP5
AceView (NCBI)SENP5
Genatlas (Paris)SENP5
WikiGenes205564
SOURCE (Princeton)SENP5
Genetics Home Reference (NIH)SENP5
Genomic and cartography
GoldenPath hg38 (UCSC)SENP5  -     chr3:196867856-196934713 +  3q29   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SENP5  -     3q29   [Description]    (hg19-Feb_2009)
EnsemblSENP5 - 3q29 [CytoView hg19]  SENP5 - 3q29 [CytoView hg38]
Mapping of homologs : NCBISENP5 [Mapview hg19]  SENP5 [Mapview hg38]
OMIM612845   
Gene and transcription
Genbank (Entrez)AF335474 AK124389 AK302305 AK313764 AL049229
RefSeq transcript (Entrez)NM_001308045 NM_152699
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SENP5
Cluster EST : UnigeneHs.240770 [ NCBI ]
CGAP (NCI)Hs.240770
Alternative Splicing GalleryENSG00000119231
Gene ExpressionSENP5 [ NCBI-GEO ]   SENP5 [ EBI - ARRAY_EXPRESS ]   SENP5 [ SEEK ]   SENP5 [ MEM ]
Gene Expression Viewer (FireBrowse)SENP5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)205564
GTEX Portal (Tissue expression)SENP5
Human Protein AtlasENSG00000119231-SENP5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96HI0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96HI0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96HI0
Splice isoforms : SwissVarQ96HI0
Catalytic activity : Enzyme3.4.22.68 [ Enzyme-Expasy ]   3.4.22.683.4.22.68 [ IntEnz-EBI ]   3.4.22.68 [ BRENDA ]   3.4.22.68 [ KEGG ]   
PhosPhoSitePlusQ96HI0
Domaine pattern : Prosite (Expaxy)ULP_PROTEASE (PS50600)   
Domains : Interpro (EBI)Peptidase_C48_C    SENP5   
Domain families : Pfam (Sanger)Peptidase_C48 (PF02902)   
Domain families : Pfam (NCBI)pfam02902   
Conserved Domain (NCBI)SENP5
DMDM Disease mutations205564
Blocks (Seattle)SENP5
SuperfamilyQ96HI0
Human Protein Atlas [tissue]ENSG00000119231-SENP5 [tissue]
Peptide AtlasQ96HI0
HPRD10222
IPIIPI00063106   IPI00909510   IPI00924623   IPI00925276   IPI00925458   
Protein Interaction databases
DIP (DOE-UCLA)Q96HI0
IntAct (EBI)Q96HI0
FunCoupENSG00000119231
BioGRIDSENP5
STRING (EMBL)SENP5
ZODIACSENP5
Ontologies - Pathways
QuickGOQ96HI0
Ontology : AmiGOendopeptidase activity  protein binding  nucleus  nucleoplasm  nucleolus  cell cycle  protein sumoylation  protein desumoylation  SUMO-specific protease activity  cell division  SUMO-specific endopeptidase activity  
Ontology : EGO-EBIendopeptidase activity  protein binding  nucleus  nucleoplasm  nucleolus  cell cycle  protein sumoylation  protein desumoylation  SUMO-specific protease activity  cell division  SUMO-specific endopeptidase activity  
NDEx NetworkSENP5
Atlas of Cancer Signalling NetworkSENP5
Wikipedia pathwaysSENP5
Orthology - Evolution
OrthoDB205564
GeneTree (enSembl)ENSG00000119231
Phylogenetic Trees/Animal Genes : TreeFamSENP5
HOVERGENQ96HI0
HOGENOMQ96HI0
Homologs : HomoloGeneSENP5
Homology/Alignments : Family Browser (UCSC)SENP5
Gene fusions - Rearrangements
Fusion : MitelmanEHHADH/SENP5 [3q27.2/3q29]  [t(3;3)(q27;q29)]  
Fusion: TCGA_MDACCSENP5 3q29 PIGZ 3q29 BRCA
Fusion: TCGA_MDACCSENP5 3q29 TCTEX1D2 3q29 LUAD
Tumor Fusion PortalSENP5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSENP5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SENP5
dbVarSENP5
ClinVarSENP5
1000_GenomesSENP5 
Exome Variant ServerSENP5
ExAC (Exome Aggregation Consortium)ENSG00000119231
GNOMAD BrowserENSG00000119231
Genetic variants : HAPMAP205564
Genomic Variants (DGV)SENP5 [DGVbeta]
DECIPHERSENP5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSENP5 
Mutations
ICGC Data PortalSENP5 
TCGA Data PortalSENP5 
Broad Tumor PortalSENP5
OASIS PortalSENP5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSENP5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSENP5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SENP5
DgiDB (Drug Gene Interaction Database)SENP5
DoCM (Curated mutations)SENP5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SENP5 (select a term)
intoGenSENP5
Cancer3DSENP5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612845   
Orphanet
DisGeNETSENP5
MedgenSENP5
Genetic Testing Registry SENP5
NextProtQ96HI0 [Medical]
TSGene205564
GENETestsSENP5
Target ValidationSENP5
Huge Navigator SENP5 [HugePedia]
snp3D : Map Gene to Disease205564
BioCentury BCIQSENP5
ClinGenSENP5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD205564
Chemical/Pharm GKB GenePA134917083
Clinical trialSENP5
Miscellaneous
canSAR (ICR)SENP5 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSENP5
EVEXSENP5
GoPubMedSENP5
iHOPSENP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:34:01 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.