SENP7 (SUMO specific peptidase 7)

2013-01-01  

Identity

HGNC
LOCATION
3q12.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 57337
MIM: 612846
HGNC: 30402
Ensembl: ENSG00000138468

Variants:

dbSNP: 57337
ClinVar: 57337
TCGA: ENSG00000138468
COSMIC: SENP7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138468ENST00000314261Q9BQF6
ENSG00000138468ENST00000348610Q9BQF6
ENSG00000138468ENST00000366089H7C1X8
ENSG00000138468ENST00000394085Q9BQF6
ENSG00000138468ENST00000394091Q9BQF6
ENSG00000138468ENST00000394094J3QT09
ENSG00000138468ENST00000394095Q9BQF6

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187994552008Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7.51
258951362015c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4.30
240184222013The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair.27
230456452012Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition.23
218786242011Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7.10
297777122018Speckle-type POZ protein suppresses hepatocellular carcinoma cell migration and invasion via ubiquitin-dependent proteolysis of SUMO1/sentrin specific peptidase 7.4
284297432017Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation.1

Citation

Dessen P

SENP7 (SUMO specific peptidase 7)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53148/senp7