Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SEPHS2 (selenophosphate synthetase 2)

Identity

Alias_symbol (synonym)SPS2
SPS2b
Other alias
HGNC (Hugo) SEPHS2
LocusID (NCBI) 22928
Atlas_Id 73119
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 30443625 and ends at 30445975 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CRP (1q23.2) / SEPHS2 (16p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEPHS2   19686
Cards
Entrez_Gene (NCBI)SEPHS2  22928  selenophosphate synthetase 2
AliasesSPS2; SPS2b
GeneCards (Weizmann)SEPHS2
Ensembl hg19 (Hinxton)ENSG00000179918 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179918 [Gene_View]  chr16:30443625-30445975 [Contig_View]  SEPHS2 [Vega]
ICGC DataPortalENSG00000179918
TCGA cBioPortalSEPHS2
AceView (NCBI)SEPHS2
Genatlas (Paris)SEPHS2
WikiGenes22928
SOURCE (Princeton)SEPHS2
Genetics Home Reference (NIH)SEPHS2
Genomic and cartography
GoldenPath hg38 (UCSC)SEPHS2  -     chr16:30443625-30445975 -  16p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEPHS2  -     16p11.2   [Description]    (hg19-Feb_2009)
EnsemblSEPHS2 - 16p11.2 [CytoView hg19]  SEPHS2 - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBISEPHS2 [Mapview hg19]  SEPHS2 [Mapview hg38]
OMIM606218   
Gene and transcription
Genbank (Entrez)AK092003 AK093889 AK303275 BC002381 BC016643
RefSeq transcript (Entrez)NM_012248
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEPHS2
Cluster EST : UnigeneHs.118725 [ NCBI ]
CGAP (NCI)Hs.118725
Alternative Splicing GalleryENSG00000179918
Gene ExpressionSEPHS2 [ NCBI-GEO ]   SEPHS2 [ EBI - ARRAY_EXPRESS ]   SEPHS2 [ SEEK ]   SEPHS2 [ MEM ]
Gene Expression Viewer (FireBrowse)SEPHS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22928
GTEX Portal (Tissue expression)SEPHS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99611   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99611  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99611
Splice isoforms : SwissVarQ99611
Catalytic activity : Enzyme2.7.9.3 [ Enzyme-Expasy ]   2.7.9.32.7.9.3 [ IntEnz-EBI ]   2.7.9.3 [ BRENDA ]   2.7.9.3 [ KEGG ]   
PhosPhoSitePlusQ99611
Domains : Interpro (EBI)AIR_synth_C_dom    PurM-like_N    SPS/SelD   
Domain families : Pfam (Sanger)AIRS (PF00586)    AIRS_C (PF02769)   
Domain families : Pfam (NCBI)pfam00586    pfam02769   
Conserved Domain (NCBI)SEPHS2
DMDM Disease mutations22928
Blocks (Seattle)SEPHS2
SuperfamilyQ99611
Human Protein AtlasENSG00000179918
Peptide AtlasQ99611
HPRD12096
IPIIPI00657969   IPI00658162   IPI00016906   
Protein Interaction databases
DIP (DOE-UCLA)Q99611
IntAct (EBI)Q99611
FunCoupENSG00000179918
BioGRIDSEPHS2
STRING (EMBL)SEPHS2
ZODIACSEPHS2
Ontologies - Pathways
QuickGOQ99611
Ontology : AmiGOselenium compound metabolic process  selenide, water dikinase activity  ATP binding  cellular_component  selenocysteine biosynthetic process  phosphorylation  
Ontology : EGO-EBIselenium compound metabolic process  selenide, water dikinase activity  ATP binding  cellular_component  selenocysteine biosynthetic process  phosphorylation  
Pathways : KEGGSelenocompound metabolism   
NDEx NetworkSEPHS2
Atlas of Cancer Signalling NetworkSEPHS2
Wikipedia pathwaysSEPHS2
Orthology - Evolution
OrthoDB22928
GeneTree (enSembl)ENSG00000179918
Phylogenetic Trees/Animal Genes : TreeFamSEPHS2
HOVERGENQ99611
HOGENOMQ99611
Homologs : HomoloGeneSEPHS2
Homology/Alignments : Family Browser (UCSC)SEPHS2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEPHS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEPHS2
dbVarSEPHS2
ClinVarSEPHS2
1000_GenomesSEPHS2 
Exome Variant ServerSEPHS2
ExAC (Exome Aggregation Consortium)SEPHS2 (select the gene name)
Genetic variants : HAPMAP22928
Genomic Variants (DGV)SEPHS2 [DGVbeta]
DECIPHERSEPHS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEPHS2 
Mutations
ICGC Data PortalSEPHS2 
TCGA Data PortalSEPHS2 
Broad Tumor PortalSEPHS2
OASIS PortalSEPHS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEPHS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEPHS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEPHS2
DgiDB (Drug Gene Interaction Database)SEPHS2
DoCM (Curated mutations)SEPHS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEPHS2 (select a term)
intoGenSEPHS2
Cancer3DSEPHS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606218   
Orphanet
MedgenSEPHS2
Genetic Testing Registry SEPHS2
NextProtQ99611 [Medical]
TSGene22928
GENETestsSEPHS2
Target ValidationSEPHS2
Huge Navigator SEPHS2 [HugePedia]
snp3D : Map Gene to Disease22928
BioCentury BCIQSEPHS2
ClinGenSEPHS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22928
Chemical/Pharm GKB GenePA134868765
Clinical trialSEPHS2
Miscellaneous
canSAR (ICR)SEPHS2 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEPHS2
EVEXSEPHS2
GoPubMedSEPHS2
iHOPSEPHS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:37:33 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.