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SEPTIN10 (septin 10)

Identity

Alias_names11-Sep
Alias_symbol (synonym)FLJ11619
Other alias
HGNC (Hugo) SEPTIN10
LocusID (NCBI) 151011
Atlas_Id 50061
Location 2q13  [Link to chromosome band 2q13]
Location_base_pair Starts at 109542797 and ends at 109614206 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CDC42EP4 17q25.1 / SEPT10 2q13SEC24C 10q22.2 / SEPT10 2q13SEPT10 2q13 / PLCD4 2q35
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(2;10)(q13;q22) SEC24C/SEPT10
t(2;12)(q13;q21) PPP1R12A/SEPT10
t(2;17)(q13;q25) CDC42EP4/SEPT10


External links

Nomenclature
HGNC (Hugo)SEPTIN10   14349
Cards
Entrez_Gene (NCBI)SEPTIN10  151011  septin 10
Aliases11-Sep
GeneCards (Weizmann)SEPTIN10
Ensembl hg19 (Hinxton)ENSG00000186522 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186522 [Gene_View]  ENSG00000186522 [Sequence]  chr2:109542797-109614206 [Contig_View]  SEPTIN10 [Vega]
ICGC DataPortalENSG00000186522
TCGA cBioPortalSEPTIN10
AceView (NCBI)SEPTIN10
Genatlas (Paris)SEPTIN10
WikiGenes151011
SOURCE (Princeton)SEPTIN10
Genetics Home Reference (NIH)SEPTIN10
Genomic and cartography
GoldenPath hg38 (UCSC)SEPTIN10  -     chr2:109542797-109614206 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEPTIN10  -     -   [Description]    (hg19-Feb_2009)
GoldenPathSEPTIN10 - - [CytoView hg19]  SEPTIN10 - - [CytoView hg38]
ImmunoBaseENSG00000186522
Mapping of homologs : NCBISEPTIN10 [Mapview hg19]  SEPTIN10 [Mapview hg38]
OMIM611737   
Gene and transcription
Genbank (Entrez)AB208875 AF146760 AF316880 AK021681 AK022682
RefSeq transcript (Entrez)NM_001321496 NM_001321498 NM_001321499 NM_001321500 NM_001321501 NM_001321502 NM_001321503 NM_001321504 NM_001321505 NM_001321506 NM_001321507 NM_001321508 NM_001321509 NM_001321510 NM_001321511 NM_001321512 NM_001321513 NM_001321514 NM_001321515 NM_144710 NM_178584
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEPTIN10
Cluster EST : UnigeneHs.469615 [ NCBI ]
CGAP (NCI)Hs.469615
Alternative Splicing GalleryENSG00000186522
Gene ExpressionSEPTIN10 [ NCBI-GEO ]   SEPTIN10 [ EBI - ARRAY_EXPRESS ]   SEPTIN10 [ SEEK ]   SEPTIN10 [ MEM ]
Gene Expression Viewer (FireBrowse)SEPTIN10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151011
GTEX Portal (Tissue expression)SEPTIN10
Human Protein AtlasENSG00000186522-SEPTIN10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P0V9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P0V9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P0V9
Splice isoforms : SwissVarQ9P0V9
PhosPhoSitePlusQ9P0V9
Domaine pattern : Prosite (Expaxy)G_SEPTIN (PS51719)   
Domains : Interpro (EBI)G_SEPTIN_dom    P-loop_NTPase    Septin   
Domain families : Pfam (Sanger)Septin (PF00735)   
Domain families : Pfam (NCBI)pfam00735   
Conserved Domain (NCBI)SEPTIN10
DMDM Disease mutations151011
Blocks (Seattle)SEPTIN10
SuperfamilyQ9P0V9
Human Protein Atlas [tissue]ENSG00000186522-SEPTIN10 [tissue]
Peptide AtlasQ9P0V9
HPRD15325
IPIIPI00374970   IPI00872036   IPI00921858   IPI00412153   IPI00873459   IPI00926875   IPI00927054   IPI00927577   IPI00927824   IPI00924731   IPI01015889   IPI01013389   
Protein Interaction databases
DIP (DOE-UCLA)Q9P0V9
IntAct (EBI)Q9P0V9
FunCoupENSG00000186522
BioGRIDSEPTIN10
STRING (EMBL)SEPTIN10
ZODIACSEPTIN10
Ontologies - Pathways
QuickGOQ9P0V9
Ontology : AmiGOGTPase activity  protein binding  GTP binding  septin ring  microtubule cytoskeleton  septin complex  cytoskeleton-dependent cytokinesis  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  septin ring  microtubule cytoskeleton  septin complex  cytoskeleton-dependent cytokinesis  
NDEx NetworkSEPTIN10
Atlas of Cancer Signalling NetworkSEPTIN10
Wikipedia pathwaysSEPTIN10
Orthology - Evolution
OrthoDB151011
GeneTree (enSembl)ENSG00000186522
Phylogenetic Trees/Animal Genes : TreeFamSEPTIN10
HOGENOMQ9P0V9
Homologs : HomoloGeneSEPTIN10
Homology/Alignments : Family Browser (UCSC)SEPTIN10
Gene fusions - Rearrangements
Fusion : MitelmanCDC42EP4/SEPT10 [17q25.1/2q13]  [t(2;17)(q13;q25)]  
Fusion : MitelmanPPP1R12A/SEPT10 [12q21.2/2q13]  [t(2;12)(q13;q21)]  
Fusion : MitelmanSEC24C/SEPT10 [10q22.2/2q13]  [t(2;10)(q13;q22)]  
Fusion PortalCDC42EP4 17q25.1 SEPT10 2q13 LUSC
Fusion PortalSEC24C 10q22.2 SEPT10 2q13 PRAD
Fusion PortalSEPT10 2q13 PLCD4 2q35 LGG
Fusion : QuiverSEPTIN10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEPTIN10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEPTIN10
dbVarSEPTIN10
ClinVarSEPTIN10
1000_GenomesSEPTIN10 
Exome Variant ServerSEPTIN10
ExAC (Exome Aggregation Consortium)ENSG00000186522
GNOMAD BrowserENSG00000186522
Varsome BrowserSEPTIN10
Genetic variants : HAPMAP151011
Genomic Variants (DGV)SEPTIN10 [DGVbeta]
DECIPHERSEPTIN10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEPTIN10 
Mutations
ICGC Data PortalSEPTIN10 
TCGA Data PortalSEPTIN10 
Broad Tumor PortalSEPTIN10
OASIS PortalSEPTIN10 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSEPTIN10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEPTIN10
DgiDB (Drug Gene Interaction Database)SEPTIN10
DoCM (Curated mutations)SEPTIN10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEPTIN10 (select a term)
intoGenSEPTIN10
Cancer3DSEPTIN10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611737   
Orphanet
DisGeNETSEPTIN10
MedgenSEPTIN10
Genetic Testing Registry SEPTIN10
NextProtQ9P0V9 [Medical]
TSGene151011
GENETestsSEPTIN10
Target ValidationSEPTIN10
Huge Navigator SEPTIN10 [HugePedia]
snp3D : Map Gene to Disease151011
BioCentury BCIQSEPTIN10
ClinGenSEPTIN10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151011
Chemical/Pharm GKB GenePA134918683
Clinical trialSEPTIN10
Miscellaneous
canSAR (ICR)SEPTIN10 (select the gene name)
DataMed IndexSEPTIN10
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEPTIN10
EVEXSEPTIN10
GoPubMedSEPTIN10
iHOPSEPTIN10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 18:06:48 CET 2019

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