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SERF1A (small EDRK-rich factor 1A)

Identity

Alias (NCBI)4F5
FAM2A
H4F5
SERF1
SMAM1
HGNC (Hugo) SERF1A
HGNC Alias symbH4F5
4F5
FAM2A
SMAM1
HGNC Alias nameSMA modifier 1
 spinal muscular atrophy-related gene H4F5
HGNC Previous nameSERF1
HGNC Previous namesmall EDRK-rich factor 1A (telomeric)
LocusID (NCBI) 8293
Atlas_Id 73131
Location 5q13.2  [Link to chromosome band 5q13]
Location_base_pair Starts at 70025251 and ends at 70032696 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SERF1A   10755
Cards
Entrez_Gene (NCBI)SERF1A    small EDRK-rich factor 1A
Aliases4F5; FAM2A; H4F5; SERF1; 
SMAM1
GeneCards (Weizmann)SERF1A
Ensembl hg19 (Hinxton)ENSG00000172058 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172058 [Gene_View]  ENSG00000172058 [Sequence]  chr5:70025251-70032696 [Contig_View]  SERF1A [Vega]
ICGC DataPortalENSG00000172058
TCGA cBioPortalSERF1A
AceView (NCBI)SERF1A
Genatlas (Paris)SERF1A
SOURCE (Princeton)SERF1A
Genetics Home Reference (NIH)SERF1A
Genomic and cartography
GoldenPath hg38 (UCSC)SERF1A  -     chr5:70025251-70032696 +  5q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERF1A  -     5q13.2   [Description]    (hg19-Feb_2009)
GoldenPathSERF1A - 5q13.2 [CytoView hg19]  SERF1A - 5q13.2 [CytoView hg38]
ImmunoBaseENSG00000172058
Genome Data Viewer NCBISERF1A [Mapview hg19]  
OMIM603011   
Gene and transcription
Genbank (Entrez)AF073518 AF073519 AF073520 BC021174 BC035932
RefSeq transcript (Entrez)NM_021967 NM_022968
Consensus coding sequences : CCDS (NCBI)SERF1A
Gene ExpressionSERF1A [ NCBI-GEO ]   SERF1A [ EBI - ARRAY_EXPRESS ]   SERF1A [ SEEK ]   SERF1A [ MEM ]
Gene Expression Viewer (FireBrowse)SERF1A [ Firebrowse - Broad ]
GenevisibleExpression of SERF1A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8293
GTEX Portal (Tissue expression)SERF1A
Human Protein AtlasENSG00000172058-SERF1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75920   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75920  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75920
PhosPhoSitePlusO75920
Domains : Interpro (EBI)SERF1/2    Uncharacterised_SERF_N   
Domain families : Pfam (Sanger)4F5 (PF04419)   
Domain families : Pfam (NCBI)pfam04419   
Conserved Domain (NCBI)SERF1A
SuperfamilyO75920
AlphaFold pdb e-kbO75920   
Human Protein Atlas [tissue]ENSG00000172058-SERF1A [tissue]
HPRD04308
Protein Interaction databases
DIP (DOE-UCLA)O75920
IntAct (EBI)O75920
BioGRIDSERF1A
STRING (EMBL)SERF1A
ZODIACSERF1A
Ontologies - Pathways
QuickGOO75920
Ontology : AmiGOmolecular_function  protein binding  nucleus  cytosol  nervous system development  protein destabilization  protein-containing complex  amyloid fibril formation  
Ontology : EGO-EBImolecular_function  protein binding  nucleus  cytosol  nervous system development  protein destabilization  protein-containing complex  amyloid fibril formation  
NDEx NetworkSERF1A
Atlas of Cancer Signalling NetworkSERF1A
Wikipedia pathwaysSERF1A
Orthology - Evolution
OrthoDB8293
GeneTree (enSembl)ENSG00000172058
Phylogenetic Trees/Animal Genes : TreeFamSERF1A
Homologs : HomoloGeneSERF1A
Homology/Alignments : Family Browser (UCSC)SERF1A
Gene fusions - Rearrangements
Fusion : QuiverSERF1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERF1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERF1A
dbVarSERF1A
ClinVarSERF1A
MonarchSERF1A
1000_GenomesSERF1A 
Exome Variant ServerSERF1A
GNOMAD BrowserENSG00000172058
Varsome BrowserSERF1A
ACMGSERF1A variants
VarityO75920
Genomic Variants (DGV)SERF1A [DGVbeta]
DECIPHERSERF1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERF1A 
Mutations
ICGC Data PortalSERF1A 
TCGA Data PortalSERF1A 
Broad Tumor PortalSERF1A
OASIS PortalSERF1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERF1A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSERF1A
Mutations and Diseases : HGMDSERF1A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSERF1A
DgiDB (Drug Gene Interaction Database)SERF1A
DoCM (Curated mutations)SERF1A
CIViC (Clinical Interpretations of Variants in Cancer)SERF1A
Cancer3DSERF1A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603011   
Orphanet
DisGeNETSERF1A
MedgenSERF1A
Genetic Testing Registry SERF1A
NextProtO75920 [Medical]
GENETestsSERF1A
Target ValidationSERF1A
Huge Navigator SERF1A [HugePedia]
ClinGenSERF1A
Clinical trials, drugs, therapy
MyCancerGenomeSERF1A
Protein Interactions : CTDSERF1A
Pharm GKB GenePA35675
PharosO75920
Clinical trialSERF1A
Miscellaneous
canSAR (ICR)SERF1A
HarmonizomeSERF1A
ARCHS4SERF1A
DataMed IndexSERF1A
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSERF1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 19:23:40 CET 2022

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