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SERF2 (small EDRK-rich factor 2)

Identity

Alias (NCBI)4F5REL
FAM2C
H4F5REL
HsT17089
HGNC (Hugo) SERF2
HGNC Alias symbH4F5rel
4F5REL
FAM2C
HsT17089
LocusID (NCBI) 10169
Atlas_Id 54609
Location 15q15.3  [Link to chromosome band 15q15]
Location_base_pair Starts at 43792320 and ends at 43796079 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MBTPS1 (16q23.3) / SERF2 (15q15.3)SERF2 (15q15.3) / HYPK (15q15.3)SERF2 (15q15.3) / PDIA3 (15q15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(15;15)(q15;q15) WDR76/SERF2


External links

 

Nomenclature
HGNC (Hugo)SERF2   10757
Cards
Entrez_Gene (NCBI)SERF2    small EDRK-rich factor 2
Aliases4F5REL; FAM2C; H4F5REL; HsT17089
GeneCards (Weizmann)SERF2
Ensembl hg19 (Hinxton)ENSG00000140264 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140264 [Gene_View]  ENSG00000140264 [Sequence]  chr15:43792320-43796079 [Contig_View]  SERF2 [Vega]
ICGC DataPortalENSG00000140264
TCGA cBioPortalSERF2
AceView (NCBI)SERF2
Genatlas (Paris)SERF2
SOURCE (Princeton)SERF2
Genetics Home Reference (NIH)SERF2
Genomic and cartography
GoldenPath hg38 (UCSC)SERF2  -     chr15:43792320-43796079 +  15q15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERF2  -     15q15.3   [Description]    (hg19-Feb_2009)
GoldenPathSERF2 - 15q15.3 [CytoView hg19]  SERF2 - 15q15.3 [CytoView hg38]
ImmunoBaseENSG00000140264
Genome Data Viewer NCBISERF2 [Mapview hg19]  
OMIM605054   
Gene and transcription
Genbank (Entrez)AF073298 AF320073 AK000479 AK094846 AK307547
RefSeq transcript (Entrez)NM_001018108 NM_001199875 NM_001199876 NM_001199877 NM_001199878 NM_005770
Consensus coding sequences : CCDS (NCBI)SERF2
Gene ExpressionSERF2 [ NCBI-GEO ]   SERF2 [ EBI - ARRAY_EXPRESS ]   SERF2 [ SEEK ]   SERF2 [ MEM ]
Gene Expression Viewer (FireBrowse)SERF2 [ Firebrowse - Broad ]
GenevisibleExpression of SERF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10169
GTEX Portal (Tissue expression)SERF2
Human Protein AtlasENSG00000140264-SERF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP84101   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP84101  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP84101
PhosPhoSitePlusP84101
Domains : Interpro (EBI)SERF1/2    Uncharacterised_SERF_N   
Domain families : Pfam (Sanger)4F5 (PF04419)   
Domain families : Pfam (NCBI)pfam04419   
Conserved Domain (NCBI)SERF2
SuperfamilyP84101
AlphaFold pdb e-kbP84101   
Human Protein Atlas [tissue]ENSG00000140264-SERF2 [tissue]
HPRD05447
Protein Interaction databases
DIP (DOE-UCLA)P84101
IntAct (EBI)P84101
BioGRIDSERF2
STRING (EMBL)SERF2
ZODIACSERF2
Ontologies - Pathways
QuickGOP84101
Ontology : AmiGOmolecular_function  nucleus  cytosol  protein destabilization  
Ontology : EGO-EBImolecular_function  nucleus  cytosol  protein destabilization  
NDEx NetworkSERF2
Atlas of Cancer Signalling NetworkSERF2
Wikipedia pathwaysSERF2
Orthology - Evolution
OrthoDB10169
GeneTree (enSembl)ENSG00000140264
Phylogenetic Trees/Animal Genes : TreeFamSERF2
Homologs : HomoloGeneSERF2
Homology/Alignments : Family Browser (UCSC)SERF2
Gene fusions - Rearrangements
Fusion : MitelmanMBTPS1/SERF2 [16q23.3/15q15.3]  
Fusion : MitelmanSERF2/PDIA3 [15q15.3/15q15.3]  
Fusion : QuiverSERF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERF2
dbVarSERF2
ClinVarSERF2
MonarchSERF2
1000_GenomesSERF2 
Exome Variant ServerSERF2
GNOMAD BrowserENSG00000140264
Varsome BrowserSERF2
ACMGSERF2 variants
VarityP84101
Genomic Variants (DGV)SERF2 [DGVbeta]
DECIPHERSERF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERF2 
Mutations
ICGC Data PortalSERF2 
TCGA Data PortalSERF2 
Broad Tumor PortalSERF2
OASIS PortalSERF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERF2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSERF2
Mutations and Diseases : HGMDSERF2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSERF2
DgiDB (Drug Gene Interaction Database)SERF2
DoCM (Curated mutations)SERF2
CIViC (Clinical Interpretations of Variants in Cancer)SERF2
Cancer3DSERF2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605054   
Orphanet
DisGeNETSERF2
MedgenSERF2
Genetic Testing Registry SERF2
NextProtP84101 [Medical]
GENETestsSERF2
Target ValidationSERF2
Huge Navigator SERF2 [HugePedia]
ClinGenSERF2
Clinical trials, drugs, therapy
MyCancerGenomeSERF2
Protein Interactions : CTDSERF2
Pharm GKB GenePA35677
PharosP84101
Clinical trialSERF2
Miscellaneous
canSAR (ICR)SERF2
HarmonizomeSERF2
DataMed IndexSERF2
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSERF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:30:37 CEST 2021

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