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SERINC3 (serine incorporator 3)

Identity

Alias_namesTDE1
tumor differentially expressed 1
Alias_symbol (synonym)DIFF33
TDE
SBBI99
TMS-1
AIGP1
Other alias
HGNC (Hugo) SERINC3
LocusID (NCBI) 10955
Atlas_Id 42502
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 43127901 and ends at 43150726 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
F2R (5q13.3) / SERINC3 (20q13.12)PRG2 (11q12.1) / SERINC3 (20q13.12)SERINC3 (20q13.12) / LOC100507412 (-)
SERINC3 (20q13.12) / RND2 (17q21.31)SERINC3 (20q13.12) / SERINC3 (20q13.12)SERINC3 (20q13.12) / TWSG1 (18p11.22)
SERINC3 (20q13.12) / ZCCHC7 (9p13.2)SHISA5 (3p21.31) / SERINC3 (20q13.12)ZCCHC7 (9p13.2) / SERINC3 (20q13.12)
SERINC3 20q13.12 / TWSG1 18p11.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERINC3   11699
Cards
Entrez_Gene (NCBI)SERINC3  10955  serine incorporator 3
AliasesAIGP1; DIFF33; SBBI99; TDE; 
TDE1; TMS-1
GeneCards (Weizmann)SERINC3
Ensembl hg19 (Hinxton)ENSG00000132824 [Gene_View]  chr20:43127901-43150726 [Contig_View]  SERINC3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000132824 [Gene_View]  chr20:43127901-43150726 [Contig_View]  SERINC3 [Vega]
ICGC DataPortalENSG00000132824
TCGA cBioPortalSERINC3
AceView (NCBI)SERINC3
Genatlas (Paris)SERINC3
WikiGenes10955
SOURCE (Princeton)SERINC3
Genetics Home Reference (NIH)SERINC3
Genomic and cartography
GoldenPath hg19 (UCSC)SERINC3  -     chr20:43127901-43150726 -  20q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SERINC3  -     20q13.12   [Description]    (hg38-Dec_2013)
EnsemblSERINC3 - 20q13.12 [CytoView hg19]  SERINC3 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBISERINC3 [Mapview hg19]  SERINC3 [Mapview hg38]
OMIM607165   
Gene and transcription
Genbank (Entrez)AA294859 AA772607 AF112227 AF153979 AK222923
RefSeq transcript (Entrez)NM_006811 NM_198941
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)SERINC3
Cluster EST : UnigeneHs.744982 [ NCBI ]
CGAP (NCI)Hs.744982
Alternative Splicing GalleryENSG00000132824
Gene ExpressionSERINC3 [ NCBI-GEO ]   SERINC3 [ EBI - ARRAY_EXPRESS ]   SERINC3 [ SEEK ]   SERINC3 [ MEM ]
Gene Expression Viewer (FireBrowse)SERINC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10955
GTEX Portal (Tissue expression)SERINC3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13530   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13530  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13530
Splice isoforms : SwissVarQ13530
PhosPhoSitePlusQ13530
Domains : Interpro (EBI)Serinc3    TDE1/TMS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)SERINC3
DMDM Disease mutations10955
Blocks (Seattle)SERINC3
SuperfamilyQ13530
Human Protein AtlasENSG00000132824
Peptide AtlasQ13530
HPRD06201
IPIIPI00013746   IPI00645959   IPI01009937   
Protein Interaction databases
DIP (DOE-UCLA)Q13530
IntAct (EBI)Q13530
FunCoupENSG00000132824
BioGRIDSERINC3
STRING (EMBL)SERINC3
ZODIACSERINC3
Ontologies - Pathways
QuickGOQ13530
Ontology : AmiGOGolgi membrane  plasma membrane  phosphatidylserine metabolic process  sphingolipid metabolic process  detection of virus  L-serine transmembrane transporter activity  L-serine transport  integral component of membrane  innate immune response  defense response to virus  positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIGolgi membrane  plasma membrane  phosphatidylserine metabolic process  sphingolipid metabolic process  detection of virus  L-serine transmembrane transporter activity  L-serine transport  integral component of membrane  innate immune response  defense response to virus  positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  
NDEx NetworkSERINC3
Atlas of Cancer Signalling NetworkSERINC3
Wikipedia pathwaysSERINC3
Orthology - Evolution
OrthoDB10955
GeneTree (enSembl)ENSG00000132824
Phylogenetic Trees/Animal Genes : TreeFamSERINC3
HOVERGENQ13530
HOGENOMQ13530
Homologs : HomoloGeneSERINC3
Homology/Alignments : Family Browser (UCSC)SERINC3
Gene fusions - Rearrangements
Fusion : MitelmanSERINC3/TWSG1 [20q13.12/18p11.22]  
Fusion: TCGASERINC3 20q13.12 TWSG1 18p11.22 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERINC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERINC3
dbVarSERINC3
ClinVarSERINC3
1000_GenomesSERINC3 
Exome Variant ServerSERINC3
ExAC (Exome Aggregation Consortium)SERINC3 (select the gene name)
Genetic variants : HAPMAP10955
Genomic Variants (DGV)SERINC3 [DGVbeta]
DECIPHER (Syndromes)20:43127901-43150726  ENSG00000132824
CONAN: Copy Number AnalysisSERINC3 
Mutations
ICGC Data PortalSERINC3 
TCGA Data PortalSERINC3 
Broad Tumor PortalSERINC3
OASIS PortalSERINC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERINC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERINC3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERINC3
DgiDB (Drug Gene Interaction Database)SERINC3
DoCM (Curated mutations)SERINC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERINC3 (select a term)
intoGenSERINC3
Cancer3DSERINC3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607165   
Orphanet
MedgenSERINC3
Genetic Testing Registry SERINC3
NextProtQ13530 [Medical]
TSGene10955
GENETestsSERINC3
Huge Navigator SERINC3 [HugePedia]
snp3D : Map Gene to Disease10955
BioCentury BCIQSERINC3
ClinGenSERINC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10955
Chemical/Pharm GKB GenePA36418
Clinical trialSERINC3
Miscellaneous
canSAR (ICR)SERINC3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERINC3
EVEXSERINC3
GoPubMedSERINC3
iHOPSERINC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:26:45 CET 2017

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