Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SERINC5 (serine incorporator 5)

Identity

Alias_namesC5orf12
chromosome 5 open reading frame 12
Alias_symbol (synonym)TPO1
Other alias
HGNC (Hugo) SERINC5
LocusID (NCBI) 256987
Atlas_Id 73137
Location 5q14.1  [Link to chromosome band 5q14]
Location_base_pair Starts at 79407050 and ends at 79551901 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CD44 (11p13) / SERINC5 (5q14.1)NUDT3 (6p21.31) / SERINC5 (5q14.1)OSBPL9 (1p32.3) / SERINC5 (5q14.1)
SERINC5 (5q14.1) / CDYL2 (16q23.2)SERINC5 (5q14.1) / CERK (22q13.31)SERINC5 (5q14.1) / CTC-236F12.4 ()
SERINC5 (5q14.1) / TTC39A (1p32.3)SERINC5 (5q14.1) / ZFYVE16 (5q14.1)SSBP2 (5q14.1) / SERINC5 (5q14.1)
TDRD3 (13q21.2) / SERINC5 (5q14.1)SERINC5 CTC-236F12.4SERINC5 ZFYVE16
SERINC5 CDYL2SSBP2 SERINC5OSBPL9 SERINC5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERINC5   18825
Cards
Entrez_Gene (NCBI)SERINC5  256987  serine incorporator 5
AliasesC5orf12; TPO1
GeneCards (Weizmann)SERINC5
Ensembl hg19 (Hinxton)ENSG00000164300 [Gene_View]  chr5:79407050-79551901 [Contig_View]  SERINC5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164300 [Gene_View]  chr5:79407050-79551901 [Contig_View]  SERINC5 [Vega]
ICGC DataPortalENSG00000164300
TCGA cBioPortalSERINC5
AceView (NCBI)SERINC5
Genatlas (Paris)SERINC5
WikiGenes256987
SOURCE (Princeton)SERINC5
Genetics Home Reference (NIH)SERINC5
Genomic and cartography
GoldenPath hg19 (UCSC)SERINC5  -     chr5:79407050-79551901 -  5q14.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SERINC5  -     5q14.1   [Description]    (hg38-Dec_2013)
EnsemblSERINC5 - 5q14.1 [CytoView hg19]  SERINC5 - 5q14.1 [CytoView hg38]
Mapping of homologs : NCBISERINC5 [Mapview hg19]  SERINC5 [Mapview hg38]
OMIM614551   
Gene and transcription
Genbank (Entrez)AF498273 AK026295 AK297467 BC101280 BC101281
RefSeq transcript (Entrez)NM_001174071 NM_001174072 NM_178276
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_034772 NW_004929322
Consensus coding sequences : CCDS (NCBI)SERINC5
Cluster EST : UnigeneHs.288232 [ NCBI ]
CGAP (NCI)Hs.288232
Alternative Splicing GalleryENSG00000164300
Gene ExpressionSERINC5 [ NCBI-GEO ]   SERINC5 [ EBI - ARRAY_EXPRESS ]   SERINC5 [ SEEK ]   SERINC5 [ MEM ]
Gene Expression Viewer (FireBrowse)SERINC5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)256987
GTEX Portal (Tissue expression)SERINC5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VE9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VE9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VE9
Splice isoforms : SwissVarQ86VE9
PhosPhoSitePlusQ86VE9
Domains : Interpro (EBI)Serinc5    TDE1/TMS   
Domain families : Pfam (Sanger)Serinc (PF03348)   
Domain families : Pfam (NCBI)pfam03348   
Conserved Domain (NCBI)SERINC5
DMDM Disease mutations256987
Blocks (Seattle)SERINC5
SuperfamilyQ86VE9
Human Protein AtlasENSG00000164300
Peptide AtlasQ86VE9
HPRD12828
IPIIPI00890708   IPI00966938   IPI00940254   IPI00967149   IPI00966609   
Protein Interaction databases
DIP (DOE-UCLA)Q86VE9
IntAct (EBI)Q86VE9
FunCoupENSG00000164300
BioGRIDSERINC5
STRING (EMBL)SERINC5
ZODIACSERINC5
Ontologies - Pathways
QuickGOQ86VE9
Ontology : AmiGOendoplasmic reticulum membrane  Golgi apparatus  phosphatidylserine metabolic process  sphingolipid metabolic process  phospholipid biosynthetic process  L-serine transmembrane transporter activity  L-serine transport  integral component of membrane  myelination  myelin sheath  extracellular exosome  positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity  positive regulation of serine C-palmitoyltransferase activity  
Ontology : EGO-EBIendoplasmic reticulum membrane  Golgi apparatus  phosphatidylserine metabolic process  sphingolipid metabolic process  phospholipid biosynthetic process  L-serine transmembrane transporter activity  L-serine transport  integral component of membrane  myelination  myelin sheath  extracellular exosome  positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity  positive regulation of serine C-palmitoyltransferase activity  
NDEx NetworkSERINC5
Atlas of Cancer Signalling NetworkSERINC5
Wikipedia pathwaysSERINC5
Orthology - Evolution
OrthoDB256987
GeneTree (enSembl)ENSG00000164300
Phylogenetic Trees/Animal Genes : TreeFamSERINC5
HOVERGENQ86VE9
HOGENOMQ86VE9
Homologs : HomoloGeneSERINC5
Homology/Alignments : Family Browser (UCSC)SERINC5
Gene fusions - Rearrangements
Fusion: TCGASERINC5 CTC-236F12.4
Fusion: TCGASERINC5 ZFYVE16
Fusion: TCGASERINC5 CDYL2
Fusion: TCGASSBP2 SERINC5
Fusion: TCGAOSBPL9 SERINC5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERINC5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERINC5
dbVarSERINC5
ClinVarSERINC5
1000_GenomesSERINC5 
Exome Variant ServerSERINC5
ExAC (Exome Aggregation Consortium)SERINC5 (select the gene name)
Genetic variants : HAPMAP256987
Genomic Variants (DGV)SERINC5 [DGVbeta]
DECIPHER (Syndromes)5:79407050-79551901  ENSG00000164300
CONAN: Copy Number AnalysisSERINC5 
Mutations
ICGC Data PortalSERINC5 
TCGA Data PortalSERINC5 
Broad Tumor PortalSERINC5
OASIS PortalSERINC5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERINC5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERINC5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERINC5
DgiDB (Drug Gene Interaction Database)SERINC5
DoCM (Curated mutations)SERINC5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERINC5 (select a term)
intoGenSERINC5
Cancer3DSERINC5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614551   
Orphanet
MedgenSERINC5
Genetic Testing Registry SERINC5
NextProtQ86VE9 [Medical]
TSGene256987
GENETestsSERINC5
Huge Navigator SERINC5 [HugePedia]
snp3D : Map Gene to Disease256987
BioCentury BCIQSERINC5
ClinGenSERINC5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD256987
Chemical/Pharm GKB GenePA38698
Clinical trialSERINC5
Miscellaneous
canSAR (ICR)SERINC5 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERINC5
EVEXSERINC5
GoPubMedSERINC5
iHOPSERINC5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:42:52 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.