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SERPINA1 (serpin family A member 1)

Identity

Alias (NCBI)A1A
A1AT
AAT
PI
PI1
PRO2275
alpha1AT
nNIF
HGNC (Hugo) SERPINA1
HGNC Alias symbAAT
A1A
PI1
alpha-1-antitrypsin
A1AT
alpha1AT
HGNC Alias nameprotease inhibitor 1
 anti-elastase
 alpha-1 antitrypsin
 alpha-1 proteinase inhibitor
HGNC Previous namePI
HGNC Previous nameserine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
LocusID (NCBI) 5265
Atlas_Id 46442
Location 14q32.13  [Link to chromosome band 14q32]
Location_base_pair Starts at 94376747 and ends at 94390635 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AGAP9 (10q11.22) / SERPINA1 (14q32.13)AKAP13 (15q25.3) / SERPINA1 (14q32.13)GAPDH (12p13.31) / SERPINA1 (14q32.13)
LAP3 (4p15.32) / SERPINA1 (14q32.13)LOC284232 () / SERPINA1 (14q32.13)MCL1 (1q21.3) / SERPINA1 (14q32.13)
MYH9 (22q12.3) / SERPINA1 (14q32.13)SERPINA1 (14q32.13) / ABHD14A (3p21.2)SERPINA1 (14q32.13) / AGXT2 (5p13.2)
SERPINA1 (14q32.13) / ALDOB (9q31.1)SERPINA1 (14q32.13) / ASXL2 (2p23.3)SERPINA1 (14q32.13) / CLTC (17q23.1)
SERPINA1 (14q32.13) / KIAA1217 (10p12.2)SERPINA1 (14q32.13) / KREMEN1 (22q12.1)SERPINA1 (14q32.13) / MOB2 (11p15.5)
SERPINA1 (14q32.13) / PRR12 (19q13.33)SERPINA1 (14q32.13) / PSMD2 (3q27.1)SERPINA1 (14q32.13) / RPL23 (17q12)
SERPINA1 (14q32.13) / SUMF1 (3p26.1)SERPINA1 (14q32.13) / TMEM123 (11q22.2)SERPINA1 (14q32.13) / TMEM230 (20p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)SERPINA1   8941
Cards
Entrez_Gene (NCBI)SERPINA1    serpin family A member 1
AliasesA1A; A1AT; AAT; PI; 
PI1; PRO2275; alpha1AT; nNIF
GeneCards (Weizmann)SERPINA1
Ensembl hg19 (Hinxton)ENSG00000197249 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197249 [Gene_View]  ENSG00000197249 [Sequence]  chr14:94376747-94390635 [Contig_View]  SERPINA1 [Vega]
ICGC DataPortalENSG00000197249
TCGA cBioPortalSERPINA1
AceView (NCBI)SERPINA1
Genatlas (Paris)SERPINA1
SOURCE (Princeton)SERPINA1
Genetics Home Reference (NIH)SERPINA1
Genomic and cartography
GoldenPath hg38 (UCSC)SERPINA1  -     chr14:94376747-94390635 -  14q32.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERPINA1  -     14q32.13   [Description]    (hg19-Feb_2009)
GoldenPathSERPINA1 - 14q32.13 [CytoView hg19]  SERPINA1 - 14q32.13 [CytoView hg38]
ImmunoBaseENSG00000197249
genome Data Viewer NCBISERPINA1 [Mapview hg19]  
OMIM107400   613490   
Gene and transcription
Genbank (Entrez)AA317159 AF119873 AK026174 AK315637 BC011991
RefSeq transcript (Entrez)NM_000295 NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707
Consensus coding sequences : CCDS (NCBI)SERPINA1
Alternative Splicing GalleryENSG00000197249
Gene ExpressionSERPINA1 [ NCBI-GEO ]   SERPINA1 [ EBI - ARRAY_EXPRESS ]   SERPINA1 [ SEEK ]   SERPINA1 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINA1 [ Firebrowse - Broad ]
GenevisibleExpression of SERPINA1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5265
GTEX Portal (Tissue expression)SERPINA1
Human Protein AtlasENSG00000197249-SERPINA1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)SERPINA1
Human Protein Atlas [tissue]ENSG00000197249-SERPINA1 [tissue]
HPRD02463
Protein Interaction databases
BioGRIDSERPINA1
STRING (EMBL)SERPINA1
ZODIACSERPINA1
Ontologies - Pathways
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSERPINA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Sep 15 22:36:09 CEST 2021

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