SERPINA10 (serpin family A member 10)

2011-03-01 Affiliation

Identity

HGNC

SERPINA10

LOCATION

14q32.13

LOCUSID

51156

ALIAS

PZI,ZPI

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 51156
MIM: 605271
HGNC: 15996
Ensembl: ENSG00000140093

Variants:

dbSNP: 51156
ClinVar: 51156
TCGA: ENSG00000140093
COSMIC: SERPINA10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000140093	ENST00000261994	Q9UK55
ENSG00000140093	ENST00000261994	A0A024R6I6
ENSG00000140093	ENST00000393096	Q9UK55
ENSG00000140093	ENST00000393096	A0A024R6I6
ENSG00000140093	ENST00000554173	Q9UK55
ENSG00000140093	ENST00000554173	A0A024R6I6
ENSG00000140093	ENST00000554723	G3V2W1

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
18768472	2008	Kinetic characterization of the protein Z-dependent protease inhibitor reaction with blood coagulation factor Xa.	21
16079143	2005	Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor: both active site and exosite interactions are required for inhibition.	19
16527896	2006	A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis.	16
16527896	2006	A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis.	16
20427285	2010	Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.	15
21220417	2011	Heparin is a major activator of the anticoagulant serpin, protein Z-dependent protease inhibitor.	14
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
22424030	2012	Co-localization of Protein Z, Protein Z-Dependent protease inhibitor and coagulation factor X in human colon cancer tissue: implications for coagulation regulation on tumor cells.	9
16093243	2005	Down-regulation of factor IXa in the factor Xase complex by protein Z-dependent protease inhibitor.	8

Citation

Dessen P

SERPINA10 (serpin family A member 10)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52115/serpina10