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SERPINA12 (serpin family A member 12)

Identity

Alias_namesserine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
Alias_symbol (synonym)OL-64
Vaspin
Other alias
HGNC (Hugo) SERPINA12
LocusID (NCBI) 145264
Atlas_Id 53532
Location 14q32.13  [Link to chromosome band 14q32]
Location_base_pair Starts at 94953611 and ends at 94970559 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERPINA12   18359
Cards
Entrez_Gene (NCBI)SERPINA12  145264  serpin family A member 12
AliasesOL-64
GeneCards (Weizmann)SERPINA12
Ensembl hg19 (Hinxton)ENSG00000165953 [Gene_View]  chr14:94953611-94970559 [Contig_View]  SERPINA12 [Vega]
Ensembl hg38 (Hinxton)ENSG00000165953 [Gene_View]  chr14:94953611-94970559 [Contig_View]  SERPINA12 [Vega]
ICGC DataPortalENSG00000165953
TCGA cBioPortalSERPINA12
AceView (NCBI)SERPINA12
Genatlas (Paris)SERPINA12
WikiGenes145264
SOURCE (Princeton)SERPINA12
Genetics Home Reference (NIH)SERPINA12
Genomic and cartography
GoldenPath hg19 (UCSC)SERPINA12  -     chr14:94953611-94970559 -  14q32.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SERPINA12  -     14q32.13   [Description]    (hg38-Dec_2013)
EnsemblSERPINA12 - 14q32.13 [CytoView hg19]  SERPINA12 - 14q32.13 [CytoView hg38]
Mapping of homologs : NCBISERPINA12 [Mapview hg19]  SERPINA12 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AY177692 AY326420 BC040857 HQ448570
RefSeq transcript (Entrez)NM_001304461 NM_173850
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)SERPINA12
Cluster EST : UnigeneHs.99476 [ NCBI ]
CGAP (NCI)Hs.99476
Alternative Splicing GalleryENSG00000165953
Gene ExpressionSERPINA12 [ NCBI-GEO ]   SERPINA12 [ EBI - ARRAY_EXPRESS ]   SERPINA12 [ SEEK ]   SERPINA12 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINA12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)145264
GTEX Portal (Tissue expression)SERPINA12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IW75   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IW75  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IW75
Splice isoforms : SwissVarQ8IW75
PhosPhoSitePlusQ8IW75
Domains : Interpro (EBI)Serpin_dom    Serpin_fam   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
Conserved Domain (NCBI)SERPINA12
DMDM Disease mutations145264
Blocks (Seattle)SERPINA12
PDB (SRS)4IF8    4Y3K    4Y40    5EI0   
PDB (PDBSum)4IF8    4Y3K    4Y40    5EI0   
PDB (IMB)4IF8    4Y3K    4Y40    5EI0   
PDB (RSDB)4IF8    4Y3K    4Y40    5EI0   
Structural Biology KnowledgeBase4IF8    4Y3K    4Y40    5EI0   
SCOP (Structural Classification of Proteins)4IF8    4Y3K    4Y40    5EI0   
CATH (Classification of proteins structures)4IF8    4Y3K    4Y40    5EI0   
SuperfamilyQ8IW75
Human Protein AtlasENSG00000165953
Peptide AtlasQ8IW75
HPRD18038
IPIIPI00219476   
Protein Interaction databases
DIP (DOE-UCLA)Q8IW75
IntAct (EBI)Q8IW75
FunCoupENSG00000165953
BioGRIDSERPINA12
STRING (EMBL)SERPINA12
ZODIACSERPINA12
Ontologies - Pathways
QuickGOQ8IW75
Ontology : AmiGOserine-type endopeptidase inhibitor activity  extracellular space  plasma membrane  glucose metabolic process  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  positive regulation of phosphatidylinositol 3-kinase signaling  negative regulation of gluconeogenesis  positive regulation of insulin receptor signaling pathway  negative regulation of lipid biosynthetic process  regulation of cholesterol metabolic process  regulation of triglyceride metabolic process  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  extracellular space  plasma membrane  glucose metabolic process  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  positive regulation of phosphatidylinositol 3-kinase signaling  negative regulation of gluconeogenesis  positive regulation of insulin receptor signaling pathway  negative regulation of lipid biosynthetic process  regulation of cholesterol metabolic process  regulation of triglyceride metabolic process  
NDEx NetworkSERPINA12
Atlas of Cancer Signalling NetworkSERPINA12
Wikipedia pathwaysSERPINA12
Orthology - Evolution
OrthoDB145264
GeneTree (enSembl)ENSG00000165953
Phylogenetic Trees/Animal Genes : TreeFamSERPINA12
HOVERGENQ8IW75
HOGENOMQ8IW75
Homologs : HomoloGeneSERPINA12
Homology/Alignments : Family Browser (UCSC)SERPINA12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERPINA12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERPINA12
dbVarSERPINA12
ClinVarSERPINA12
1000_GenomesSERPINA12 
Exome Variant ServerSERPINA12
ExAC (Exome Aggregation Consortium)SERPINA12 (select the gene name)
Genetic variants : HAPMAP145264
Genomic Variants (DGV)SERPINA12 [DGVbeta]
DECIPHER (Syndromes)14:94953611-94970559  ENSG00000165953
CONAN: Copy Number AnalysisSERPINA12 
Mutations
ICGC Data PortalSERPINA12 
TCGA Data PortalSERPINA12 
Broad Tumor PortalSERPINA12
OASIS PortalSERPINA12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERPINA12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERPINA12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERPINA12
DgiDB (Drug Gene Interaction Database)SERPINA12
DoCM (Curated mutations)SERPINA12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERPINA12 (select a term)
intoGenSERPINA12
Cancer3DSERPINA12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSERPINA12
Genetic Testing Registry SERPINA12
NextProtQ8IW75 [Medical]
TSGene145264
GENETestsSERPINA12
Huge Navigator SERPINA12 [HugePedia]
snp3D : Map Gene to Disease145264
BioCentury BCIQSERPINA12
ClinGenSERPINA12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD145264
Chemical/Pharm GKB GenePA134863157
Clinical trialSERPINA12
Miscellaneous
canSAR (ICR)SERPINA12 (select the gene name)
Probes
Litterature
PubMed81 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERPINA12
EVEXSERPINA12
GoPubMedSERPINA12
iHOPSERPINA12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:26:46 CET 2017

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