Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SERPINA4 (serpin family A member 4)

Identity

Alias_namesPI4
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
sserpin family A member 4
Alias_symbol (synonym)KST
KAL
KLST
kallistatin
Other aliasPI-4
HGNC (Hugo) SERPINA4
LocusID (NCBI) 5267
Atlas_Id 43896
Location 14q32.13  [Link to chromosome band 14q32]
Location_base_pair Starts at 94561420 and ends at 94569913 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERPINA4   8948
Cards
Entrez_Gene (NCBI)SERPINA4  5267  serpin family A member 4
AliasesKAL; KLST; KST; PI-4; 
PI4; kallistatin
GeneCards (Weizmann)SERPINA4
Ensembl hg19 (Hinxton)ENSG00000100665 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100665 [Gene_View]  chr14:94561420-94569913 [Contig_View]  SERPINA4 [Vega]
ICGC DataPortalENSG00000100665
TCGA cBioPortalSERPINA4
AceView (NCBI)SERPINA4
Genatlas (Paris)SERPINA4
WikiGenes5267
SOURCE (Princeton)SERPINA4
Genetics Home Reference (NIH)SERPINA4
Genomic and cartography
GoldenPath hg38 (UCSC)SERPINA4  -     chr14:94561420-94569913 +  14q32.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERPINA4  -     14q32.13   [Description]    (hg19-Feb_2009)
EnsemblSERPINA4 - 14q32.13 [CytoView hg19]  SERPINA4 - 14q32.13 [CytoView hg38]
Mapping of homologs : NCBISERPINA4 [Mapview hg19]  SERPINA4 [Mapview hg38]
OMIM147935   
Gene and transcription
Genbank (Entrez)AI273449 AK309586 AK313196 BC014992 BX248009
RefSeq transcript (Entrez)NM_001289032 NM_001289033 NM_006215
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SERPINA4
Cluster EST : UnigeneHs.719893 [ NCBI ]
CGAP (NCI)Hs.719893
Alternative Splicing GalleryENSG00000100665
Gene ExpressionSERPINA4 [ NCBI-GEO ]   SERPINA4 [ EBI - ARRAY_EXPRESS ]   SERPINA4 [ SEEK ]   SERPINA4 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5267
GTEX Portal (Tissue expression)SERPINA4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP29622   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP29622  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP29622
Splice isoforms : SwissVarP29622
PhosPhoSitePlusP29622
Domaine pattern : Prosite (Expaxy)SERPIN (PS00284)   
Domains : Interpro (EBI)Serpin_CS    Serpin_dom    Serpin_fam   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
Conserved Domain (NCBI)SERPINA4
DMDM Disease mutations5267
Blocks (Seattle)SERPINA4
SuperfamilyP29622
Human Protein AtlasENSG00000100665
Peptide AtlasP29622
HPRD01004
IPIIPI00328609   
Protein Interaction databases
DIP (DOE-UCLA)P29622
IntAct (EBI)P29622
FunCoupENSG00000100665
BioGRIDSERPINA4
STRING (EMBL)SERPINA4
ZODIACSERPINA4
Ontologies - Pathways
QuickGOP29622
Ontology : AmiGOplatelet degranulation  serine-type endopeptidase inhibitor activity  extracellular region  extracellular space  negative regulation of endopeptidase activity  platelet dense granule lumen  extracellular exosome  
Ontology : EGO-EBIplatelet degranulation  serine-type endopeptidase inhibitor activity  extracellular region  extracellular space  negative regulation of endopeptidase activity  platelet dense granule lumen  extracellular exosome  
NDEx NetworkSERPINA4
Atlas of Cancer Signalling NetworkSERPINA4
Wikipedia pathwaysSERPINA4
Orthology - Evolution
OrthoDB5267
GeneTree (enSembl)ENSG00000100665
Phylogenetic Trees/Animal Genes : TreeFamSERPINA4
HOVERGENP29622
HOGENOMP29622
Homologs : HomoloGeneSERPINA4
Homology/Alignments : Family Browser (UCSC)SERPINA4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERPINA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERPINA4
dbVarSERPINA4
ClinVarSERPINA4
1000_GenomesSERPINA4 
Exome Variant ServerSERPINA4
ExAC (Exome Aggregation Consortium)SERPINA4 (select the gene name)
Genetic variants : HAPMAP5267
Genomic Variants (DGV)SERPINA4 [DGVbeta]
DECIPHERSERPINA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERPINA4 
Mutations
ICGC Data PortalSERPINA4 
TCGA Data PortalSERPINA4 
Broad Tumor PortalSERPINA4
OASIS PortalSERPINA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERPINA4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERPINA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERPINA4
DgiDB (Drug Gene Interaction Database)SERPINA4
DoCM (Curated mutations)SERPINA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERPINA4 (select a term)
intoGenSERPINA4
Cancer3DSERPINA4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147935   
Orphanet
MedgenSERPINA4
Genetic Testing Registry SERPINA4
NextProtP29622 [Medical]
TSGene5267
GENETestsSERPINA4
Target ValidationSERPINA4
Huge Navigator SERPINA4 [HugePedia]
snp3D : Map Gene to Disease5267
BioCentury BCIQSERPINA4
ClinGenSERPINA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5267
Chemical/Pharm GKB GenePA35514
Clinical trialSERPINA4
Miscellaneous
canSAR (ICR)SERPINA4 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERPINA4
EVEXSERPINA4
GoPubMedSERPINA4
iHOPSERPINA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:14:06 CEST 2017

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