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SERPINA6 (serpin family A member 6)

Identity

Alias_namesCBG
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
Other alias
HGNC (Hugo) SERPINA6
LocusID (NCBI) 866
Atlas_Id 56521
Location 14q32.13  [Link to chromosome band 14q32]
Location_base_pair Starts at 94304248 and ends at 94323351 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERPINA6   1540
Cards
Entrez_Gene (NCBI)SERPINA6  866  serpin family A member 6
AliasesCBG
GeneCards (Weizmann)SERPINA6
Ensembl hg19 (Hinxton)ENSG00000170099 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170099 [Gene_View]  chr14:94304248-94323351 [Contig_View]  SERPINA6 [Vega]
ICGC DataPortalENSG00000170099
TCGA cBioPortalSERPINA6
AceView (NCBI)SERPINA6
Genatlas (Paris)SERPINA6
WikiGenes866
SOURCE (Princeton)SERPINA6
Genetics Home Reference (NIH)SERPINA6
Genomic and cartography
GoldenPath hg38 (UCSC)SERPINA6  -     chr14:94304248-94323351 -  14q32.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERPINA6  -     14q32.13   [Description]    (hg19-Feb_2009)
EnsemblSERPINA6 - 14q32.13 [CytoView hg19]  SERPINA6 - 14q32.13 [CytoView hg38]
Mapping of homologs : NCBISERPINA6 [Mapview hg19]  SERPINA6 [Mapview hg38]
OMIM122500   611489   
Gene and transcription
Genbank (Entrez)AK225591 AK290821 AK313760 AM392605 AM392608
RefSeq transcript (Entrez)NM_001756
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_011796 NT_187601
Consensus coding sequences : CCDS (NCBI)SERPINA6
Cluster EST : UnigeneHs.532635 [ NCBI ]
CGAP (NCI)Hs.532635
Alternative Splicing GalleryENSG00000170099
Gene ExpressionSERPINA6 [ NCBI-GEO ]   SERPINA6 [ EBI - ARRAY_EXPRESS ]   SERPINA6 [ SEEK ]   SERPINA6 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINA6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)866
GTEX Portal (Tissue expression)SERPINA6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08185   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08185  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08185
Splice isoforms : SwissVarP08185
PhosPhoSitePlusP08185
Domaine pattern : Prosite (Expaxy)SERPIN (PS00284)   
Domains : Interpro (EBI)Serpin_CS    Serpin_dom    Serpin_fam   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
Conserved Domain (NCBI)SERPINA6
DMDM Disease mutations866
Blocks (Seattle)SERPINA6
PDB (SRS)2VDX    2VDY    4BB2    4C41    4C49   
PDB (PDBSum)2VDX    2VDY    4BB2    4C41    4C49   
PDB (IMB)2VDX    2VDY    4BB2    4C41    4C49   
PDB (RSDB)2VDX    2VDY    4BB2    4C41    4C49   
Structural Biology KnowledgeBase2VDX    2VDY    4BB2    4C41    4C49   
SCOP (Structural Classification of Proteins)2VDX    2VDY    4BB2    4C41    4C49   
CATH (Classification of proteins structures)2VDX    2VDY    4BB2    4C41    4C49   
SuperfamilyP08185
Human Protein AtlasENSG00000170099
Peptide AtlasP08185
HPRD00419
IPIIPI00027482   IPI01025848   IPI01026430   
Protein Interaction databases
DIP (DOE-UCLA)P08185
IntAct (EBI)P08185
FunCoupENSG00000170099
BioGRIDSERPINA6
STRING (EMBL)SERPINA6
ZODIACSERPINA6
Ontologies - Pathways
QuickGOP08185
Ontology : AmiGOserine-type endopeptidase inhibitor activity  steroid binding  extracellular space  transport  glucocorticoid metabolic process  negative regulation of endopeptidase activity  extracellular exosome  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  steroid binding  extracellular space  transport  glucocorticoid metabolic process  negative regulation of endopeptidase activity  extracellular exosome  
NDEx NetworkSERPINA6
Atlas of Cancer Signalling NetworkSERPINA6
Wikipedia pathwaysSERPINA6
Orthology - Evolution
OrthoDB866
GeneTree (enSembl)ENSG00000170099
Phylogenetic Trees/Animal Genes : TreeFamSERPINA6
HOVERGENP08185
HOGENOMP08185
Homologs : HomoloGeneSERPINA6
Homology/Alignments : Family Browser (UCSC)SERPINA6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERPINA6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERPINA6
dbVarSERPINA6
ClinVarSERPINA6
1000_GenomesSERPINA6 
Exome Variant ServerSERPINA6
ExAC (Exome Aggregation Consortium)SERPINA6 (select the gene name)
Genetic variants : HAPMAP866
Genomic Variants (DGV)SERPINA6 [DGVbeta]
DECIPHERSERPINA6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERPINA6 
Mutations
ICGC Data PortalSERPINA6 
TCGA Data PortalSERPINA6 
Broad Tumor PortalSERPINA6
OASIS PortalSERPINA6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERPINA6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERPINA6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERPINA6
DgiDB (Drug Gene Interaction Database)SERPINA6
DoCM (Curated mutations)SERPINA6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERPINA6 (select a term)
intoGenSERPINA6
Cancer3DSERPINA6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM122500    611489   
Orphanet18381   
MedgenSERPINA6
Genetic Testing Registry SERPINA6
NextProtP08185 [Medical]
TSGene866
GENETestsSERPINA6
Target ValidationSERPINA6
Huge Navigator SERPINA6 [HugePedia]
snp3D : Map Gene to Disease866
BioCentury BCIQSERPINA6
ClinGenSERPINA6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD866
Chemical/Pharm GKB GenePA35033
Clinical trialSERPINA6
Miscellaneous
canSAR (ICR)SERPINA6 (select the gene name)
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERPINA6
EVEXSERPINA6
GoPubMedSERPINA6
iHOPSERPINA6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:54:59 CEST 2017

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