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SERPINB13 (serpin family B member 13)

Identity

Alias_namesPI13
serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
Alias_symbol (synonym)HUR7
hurpin
headpin
Other aliasHSHUR7SEQ
HGNC (Hugo) SERPINB13
LocusID (NCBI) 5275
Atlas_Id 45574
Location 18q21.33  [Link to chromosome band 18q21]
Location_base_pair Starts at 63587300 and ends at 63599199 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CASC15 (6p22.3) / SERPINB13 (18q21.33)SERPINB13 (18q21.33) / GNB4 (3q26.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERPINB13   8944
Cards
Entrez_Gene (NCBI)SERPINB13  5275  serpin family B member 13
AliasesHSHUR7SEQ; HUR7; PI13; headpin
GeneCards (Weizmann)SERPINB13
Ensembl hg19 (Hinxton)ENSG00000197641 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197641 [Gene_View]  chr18:63587300-63599199 [Contig_View]  SERPINB13 [Vega]
ICGC DataPortalENSG00000197641
TCGA cBioPortalSERPINB13
AceView (NCBI)SERPINB13
Genatlas (Paris)SERPINB13
WikiGenes5275
SOURCE (Princeton)SERPINB13
Genetics Home Reference (NIH)SERPINB13
Genomic and cartography
GoldenPath hg38 (UCSC)SERPINB13  -     chr18:63587300-63599199 +  18q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERPINB13  -     18q21.33   [Description]    (hg19-Feb_2009)
EnsemblSERPINB13 - 18q21.33 [CytoView hg19]  SERPINB13 - 18q21.33 [CytoView hg38]
Mapping of homologs : NCBISERPINB13 [Mapview hg19]  SERPINB13 [Mapview hg38]
OMIM604445   
Gene and transcription
Genbank (Entrez)AF169949 AJ001696 AJ001697 AJ001698 AK290323
RefSeq transcript (Entrez)NM_001307923 NM_001348267 NM_001348268 NM_001348269 NM_001348270 NM_012397
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SERPINB13
Cluster EST : UnigeneHs.241407 [ NCBI ]
CGAP (NCI)Hs.241407
Alternative Splicing GalleryENSG00000197641
Gene ExpressionSERPINB13 [ NCBI-GEO ]   SERPINB13 [ EBI - ARRAY_EXPRESS ]   SERPINB13 [ SEEK ]   SERPINB13 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINB13 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5275
GTEX Portal (Tissue expression)SERPINB13
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UIV8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UIV8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UIV8
Splice isoforms : SwissVarQ9UIV8
PhosPhoSitePlusQ9UIV8
Domaine pattern : Prosite (Expaxy)SERPIN (PS00284)   
Domains : Interpro (EBI)Serpin_CS    Serpin_dom    Serpin_fam   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
Conserved Domain (NCBI)SERPINB13
DMDM Disease mutations5275
Blocks (Seattle)SERPINB13
SuperfamilyQ9UIV8
Human Protein AtlasENSG00000197641
Peptide AtlasQ9UIV8
HPRD05118
IPIIPI00220494   IPI00006560   IPI00792225   IPI00877737   IPI00658143   IPI00893125   IPI00893509   
Protein Interaction databases
DIP (DOE-UCLA)Q9UIV8
IntAct (EBI)Q9UIV8
FunCoupENSG00000197641
BioGRIDSERPINB13
STRING (EMBL)SERPINB13
ZODIACSERPINB13
Ontologies - Pathways
QuickGOQ9UIV8
Ontology : AmiGOprotease binding  serine-type endopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  extracellular space  nucleoplasm  nucleolus  cytoplasm  cytosol  response to UV  negative regulation of endopeptidase activity  nuclear speck  regulation of proteolysis  extracellular exosome  negative regulation of keratinocyte apoptotic process  
Ontology : EGO-EBIprotease binding  serine-type endopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  extracellular space  nucleoplasm  nucleolus  cytoplasm  cytosol  response to UV  negative regulation of endopeptidase activity  nuclear speck  regulation of proteolysis  extracellular exosome  negative regulation of keratinocyte apoptotic process  
Pathways : KEGGAmoebiasis   
NDEx NetworkSERPINB13
Atlas of Cancer Signalling NetworkSERPINB13
Wikipedia pathwaysSERPINB13
Orthology - Evolution
OrthoDB5275
GeneTree (enSembl)ENSG00000197641
Phylogenetic Trees/Animal Genes : TreeFamSERPINB13
HOVERGENQ9UIV8
HOGENOMQ9UIV8
Homologs : HomoloGeneSERPINB13
Homology/Alignments : Family Browser (UCSC)SERPINB13
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERPINB13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERPINB13
dbVarSERPINB13
ClinVarSERPINB13
1000_GenomesSERPINB13 
Exome Variant ServerSERPINB13
ExAC (Exome Aggregation Consortium)SERPINB13 (select the gene name)
Genetic variants : HAPMAP5275
Genomic Variants (DGV)SERPINB13 [DGVbeta]
DECIPHERSERPINB13 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERPINB13 
Mutations
ICGC Data PortalSERPINB13 
TCGA Data PortalSERPINB13 
Broad Tumor PortalSERPINB13
OASIS PortalSERPINB13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERPINB13  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERPINB13
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERPINB13
DgiDB (Drug Gene Interaction Database)SERPINB13
DoCM (Curated mutations)SERPINB13 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERPINB13 (select a term)
intoGenSERPINB13
Cancer3DSERPINB13(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604445   
Orphanet
MedgenSERPINB13
Genetic Testing Registry SERPINB13
NextProtQ9UIV8 [Medical]
TSGene5275
GENETestsSERPINB13
Target ValidationSERPINB13
Huge Navigator SERPINB13 [HugePedia]
snp3D : Map Gene to Disease5275
BioCentury BCIQSERPINB13
ClinGenSERPINB13
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5275
Chemical/Pharm GKB GenePA35512
Clinical trialSERPINB13
Miscellaneous
canSAR (ICR)SERPINB13 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERPINB13
EVEXSERPINB13
GoPubMedSERPINB13
iHOPSERPINB13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:14:07 CEST 2017

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