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SERPINB8 (serpin family B member 8)

Identity

Alias_namesPI8
serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
Alias_symbol (synonym)CAP2
Other aliasPI-8
PSS5
HGNC (Hugo) SERPINB8
LocusID (NCBI) 5271
Atlas_Id 50950
Location 18q22.1  [Link to chromosome band 18q22]
Location_base_pair Starts at 63970029 and ends at 63986653 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERPINB8   8952
Cards
Entrez_Gene (NCBI)SERPINB8  5271  serpin family B member 8
AliasesCAP2; PI-8; PI8; PSS5
GeneCards (Weizmann)SERPINB8
Ensembl hg19 (Hinxton)ENSG00000166401 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166401 [Gene_View]  chr18:63970029-63986653 [Contig_View]  SERPINB8 [Vega]
ICGC DataPortalENSG00000166401
TCGA cBioPortalSERPINB8
AceView (NCBI)SERPINB8
Genatlas (Paris)SERPINB8
WikiGenes5271
SOURCE (Princeton)SERPINB8
Genetics Home Reference (NIH)SERPINB8
Genomic and cartography
GoldenPath hg38 (UCSC)SERPINB8  -     chr18:63970029-63986653 +  18q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERPINB8  -     18q22.1   [Description]    (hg19-Feb_2009)
EnsemblSERPINB8 - 18q22.1 [CytoView hg19]  SERPINB8 - 18q22.1 [CytoView hg38]
Mapping of homologs : NCBISERPINB8 [Mapview hg19]  SERPINB8 [Mapview hg38]
OMIM601697   617115   
Gene and transcription
Genbank (Entrez)AK300391 AK313782 AL708543 BC034528 BE566411
RefSeq transcript (Entrez)NM_001031848 NM_001276490 NM_001348367 NM_001348368 NM_001348369 NM_001348370 NM_002640 NM_198833
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SERPINB8
Cluster EST : UnigeneHs.368077 [ NCBI ]
CGAP (NCI)Hs.368077
Alternative Splicing GalleryENSG00000166401
Gene ExpressionSERPINB8 [ NCBI-GEO ]   SERPINB8 [ EBI - ARRAY_EXPRESS ]   SERPINB8 [ SEEK ]   SERPINB8 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINB8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5271
GTEX Portal (Tissue expression)SERPINB8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50452   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50452  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50452
Splice isoforms : SwissVarP50452
PhosPhoSitePlusP50452
Domaine pattern : Prosite (Expaxy)SERPIN (PS00284)   
Domains : Interpro (EBI)Serpin_CS    Serpin_dom    Serpin_fam   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
Conserved Domain (NCBI)SERPINB8
DMDM Disease mutations5271
Blocks (Seattle)SERPINB8
SuperfamilyP50452
Human Protein AtlasENSG00000166401
Peptide AtlasP50452
HPRD03412
IPIIPI00032134   IPI01013972   IPI00375668   IPI00657847   IPI00793975   IPI00794378   
Protein Interaction databases
DIP (DOE-UCLA)P50452
IntAct (EBI)P50452
FunCoupENSG00000166401
BioGRIDSERPINB8
STRING (EMBL)SERPINB8
ZODIACSERPINB8
Ontologies - Pathways
QuickGOP50452
Ontology : AmiGOserine-type endopeptidase inhibitor activity  protein binding  extracellular space  cytosol  negative regulation of endopeptidase activity  extracellular exosome  epithelial cell-cell adhesion  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  protein binding  extracellular space  cytosol  negative regulation of endopeptidase activity  extracellular exosome  epithelial cell-cell adhesion  
NDEx NetworkSERPINB8
Atlas of Cancer Signalling NetworkSERPINB8
Wikipedia pathwaysSERPINB8
Orthology - Evolution
OrthoDB5271
GeneTree (enSembl)ENSG00000166401
Phylogenetic Trees/Animal Genes : TreeFamSERPINB8
HOVERGENP50452
HOGENOMP50452
Homologs : HomoloGeneSERPINB8
Homology/Alignments : Family Browser (UCSC)SERPINB8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERPINB8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERPINB8
dbVarSERPINB8
ClinVarSERPINB8
1000_GenomesSERPINB8 
Exome Variant ServerSERPINB8
ExAC (Exome Aggregation Consortium)SERPINB8 (select the gene name)
Genetic variants : HAPMAP5271
Genomic Variants (DGV)SERPINB8 [DGVbeta]
DECIPHERSERPINB8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERPINB8 
Mutations
ICGC Data PortalSERPINB8 
TCGA Data PortalSERPINB8 
Broad Tumor PortalSERPINB8
OASIS PortalSERPINB8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERPINB8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERPINB8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERPINB8
DgiDB (Drug Gene Interaction Database)SERPINB8
DoCM (Curated mutations)SERPINB8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERPINB8 (select a term)
intoGenSERPINB8
Cancer3DSERPINB8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601697    617115   
Orphanet
MedgenSERPINB8
Genetic Testing Registry SERPINB8
NextProtP50452 [Medical]
TSGene5271
GENETestsSERPINB8
Target ValidationSERPINB8
Huge Navigator SERPINB8 [HugePedia]
snp3D : Map Gene to Disease5271
BioCentury BCIQSERPINB8
ClinGenSERPINB8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5271
Chemical/Pharm GKB GenePA35517
Clinical trialSERPINB8
Miscellaneous
canSAR (ICR)SERPINB8 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERPINB8
EVEXSERPINB8
GoPubMedSERPINB8
iHOPSERPINB8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:14:08 CEST 2017

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