Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SERPINF1 (serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1)

Identity

Other namesEPC-1
OI12
OI6
PEDF
HGNC (Hugo) SERPINF1
LocusID (NCBI) 5176
Location 17p13.3
Location_base_pair Starts at 1665259 and ends at 1680859 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SERPINF1   8824
Cards
Entrez_Gene (NCBI)SERPINF1  5176  serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
GeneCards (Weizmann)SERPINF1
Ensembl (Hinxton)ENSG00000132386 [Gene_View]  chr17:1665259-1680859 [Contig_View]  SERPINF1 [Vega]
ICGC DataPortalENSG00000132386
cBioPortalSERPINF1
AceView (NCBI)SERPINF1
Genatlas (Paris)SERPINF1
WikiGenes5176
SOURCE (Princeton)NM_002615
Genomic and cartography
GoldenPath (UCSC)SERPINF1  -  17p13.3   chr17:1665259-1680859 +  17p13.3   [Description]    (hg19-Feb_2009)
EnsemblSERPINF1 - 17p13.3 [CytoView]
Mapping of homologs : NCBISERPINF1 [Mapview]
OMIM172860   613982   
Gene and transcription
Genbank (Entrez)AA351026 AA658568 AB593011 AB593012 AB593013
RefSeq transcript (Entrez)NM_002615
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_028180 NT_010718 NW_001838403 NW_004929405
Consensus coding sequences : CCDS (NCBI)SERPINF1
Cluster EST : UnigeneHs.532768 [ NCBI ]
CGAP (NCI)Hs.532768
Alternative Splicing : Fast-db (Paris)GSHG0012114
Alternative Splicing GalleryENSG00000132386
Gene ExpressionSERPINF1 [ NCBI-GEO ]     SERPINF1 [ SEEK ]   SERPINF1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36955 (Uniprot)
NextProtP36955  [Medical]
With graphics : InterProP36955
Splice isoforms : SwissVarP36955 (Swissvar)
Domaine pattern : Prosite (Expaxy)SERPIN (PS00284)   
Domains : Interpro (EBI)Serpin_CS [organisation]   Serpin_dom [organisation]   Serpin_fam [organisation]  
Related proteins : CluSTrP36955
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
DMDM Disease mutations5176
Blocks (Seattle)P36955
PDB (SRS)1IMV   
PDB (PDBSum)1IMV   
PDB (IMB)1IMV   
PDB (RSDB)1IMV   
Human Protein AtlasENSG00000132386 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP36955
HPRD01408
IPIIPI00006114   
Protein Interaction databases
DIP (DOE-UCLA)P36955
IntAct (EBI)P36955
FunCoupENSG00000132386
BioGRIDSERPINF1
InParanoidP36955
Interologous Interaction database P36955
IntegromeDBSERPINF1
STRING (EMBL)SERPINF1
Ontologies - Pathways
Ontology : AmiGOkidney development  serine-type endopeptidase inhibitor activity  extracellular region  extracellular space  multicellular organismal development  aging  short-term memory  cell proliferation  negative regulation of endopeptidase activity  negative regulation of angiogenesis  regulation of proteolysis  extracellular matrix  response to retinoic acid  melanosome  negative regulation of inflammatory response  positive regulation of neurogenesis  response to glucocorticoid  negative regulation of epithelial cell proliferation involved in prostate gland development  extracellular vesicular exosome  
Ontology : EGO-EBIkidney development  serine-type endopeptidase inhibitor activity  extracellular region  extracellular space  multicellular organismal development  aging  short-term memory  cell proliferation  negative regulation of endopeptidase activity  negative regulation of angiogenesis  regulation of proteolysis  extracellular matrix  response to retinoic acid  melanosome  negative regulation of inflammatory response  positive regulation of neurogenesis  response to glucocorticoid  negative regulation of epithelial cell proliferation involved in prostate gland development  extracellular vesicular exosome  
Protein Interaction DatabaseSERPINF1
Wikipedia pathwaysSERPINF1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SERPINF1
snp3D : Map Gene to Disease5176
SNP (GeneSNP Utah)SERPINF1
SNP : HGBaseSERPINF1
Genetic variants : HAPMAPSERPINF1
Exome VariantSERPINF1
1000_GenomesSERPINF1 
ICGC programENSG00000132386 
Somatic Mutations in Cancer : COSMICSERPINF1 
CONAN: Copy Number AnalysisSERPINF1 
Mutations and Diseases : HGMDSERPINF1
Genomic VariantsSERPINF1  SERPINF1 [DGVbeta]
dbVarSERPINF1
ClinVarSERPINF1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM172860    613982   
MedgenSERPINF1
GENETestsSERPINF1
Disease Genetic AssociationSERPINF1
Huge Navigator SERPINF1 [HugePedia]  SERPINF1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneSERPINF1
Homology/Alignments : Family Browser (UCSC)SERPINF1
Phylogenetic Trees/Animal Genes : TreeFamSERPINF1
Chemical/Protein Interactions : CTD5176
Chemical/Pharm GKB GenePA35508
Clinical trialSERPINF1
Cancer Resource (Charite)ENSG00000132386
Other databases
Probes
Litterature
PubMed196 Pubmed reference(s) in Entrez
CoreMineSERPINF1
iHOPSERPINF1
OncoSearchSERPINF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:14:57 CEST 2014

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