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SERPINF1 (serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1)

Identity

Other namesEPC-1
OI12
OI6
PEDF
HGNC (Hugo) SERPINF1
LocusID (NCBI) 5176
Location 17p13.3
Location_base_pair Starts at 1665259 and ends at 1680859 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SERPINF1   8824
Entrez_Gene (NCBI)SERPINF1  5176  serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Cards
GeneCards (Weizmann)SERPINF1
Ensembl (Hinxton)ENSG00000132386 [Gene_View]  chr17:1665259-1680859 [Contig_View]  SERPINF1 [Vega]
AceView (NCBI)SERPINF1
Genatlas (Paris)SERPINF1
SOURCE (Stanford)NM_002615
Genomic and cartography
GoldenPath (UCSC)SERPINF1  -  17p13.3   chr17:1665259-1680859 +  17p13.3   [Description]    (hg19-Feb_2009)
EnsemblSERPINF1 - 17p13.3 [CytoView]
Mapping of homologs : NCBISERPINF1 [Mapview]
OMIM172860   613982   
Gene and transcription
Genbank (Entrez)AA351026 AA658568 AB593011 AB593012 AB593013
RefSeq transcript (SRS)NM_002615
RefSeq transcript (Entrez)NM_002615
RefSeq genomic (SRS)AC_000149 NC_000017 NC_018928 NG_028180 NT_010718 NW_001838403 NW_004929405
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_028180 NT_010718 NW_001838403 NW_004929405
Consensus coding sequences : CCDS (NCBI)SERPINF1
Cluster EST : UnigeneHs.532768 [ SRS ] Hs.532768 [ NCBI ]
CGAP (NCI)Hs.532768
Alternative Splicing : Fast-db (Paris)GSHG0012114
Alternative Splicing GalleryENSG00000132386
Gene ExpressionSERPINF1 [ NCBI-GEO ]   SERPINF1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36955 (SRS) P36955 (Uniprot)
NextProtP36955  [Medical]
With graphics : InterProP36955
Splice isoforms : SwissVarP36955(Swissvar)
Domaine pattern : Prosite (SRS)SERPIN (PS00284)   
Domaine pattern : Prosite (Expaxy)SERPIN (PS00284)   
Domains : Interpro (SRS)Serpin_CS    Serpin_dom    Serpin_fam   
Domains : Interpro (EBI)Serpin_CS    Serpin_dom    Serpin_fam   
Related proteins : CluSTrP36955
Domain families : Pfam (SRS)Serpin (PF00079)   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
DMDM5176
Blocks (Seattle)P36955
PDB (SRS)1IMV   
PDB (PDBSum)1IMV   
PDB (IMB)1IMV   
PDB (RSDB)1IMV   
Human Protein AtlasENSG00000132386
HPRD01408
IPIIPI00006114   
Protein Interaction databases
DIP (DOE-UCLA)P36955
IntAct (EBI)P36955
FunCoupENSG00000132386
REACTOMESERPINF1
Protein Interaction Database5176
BioGRIDSERPINF1
InParanoidP36955
Interologous Interaction database P36955
IntegromeDBSERPINF1
Gene fusion - rearrangments
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SERPINF1
SNP (GeneSNP Utah)SERPINF1
SNP : HGBaseSERPINF1
Genetic variants : HAPMAPSERPINF1
Somatic Mutations in Cancer : COSMICSERPINF1 
CONAN: Copy Number AnalysisSERPINF1 
Mutations and Diseases : HGMDSERPINF1
OMIM172860    613982   
GENETests172860    613982   
Disease Genetic AssociationSERPINF1
Huge Navigator SERPINF1 [HugePedia]  SERPINF1 [HugeCancerGEM]
Genomic VariantsSERPINF1  SERPINF1 [DGVbeta]
ClinVarSERPINF1
snp3D : Map Gene to Disease5176
General knowledge
Homologs : HomoloGeneSERPINF1
Homology/Alignments : Family Browser (UCSC)SERPINF1
Phylogenetic Trees/Animal Genes : TreeFamSERPINF1
Chemical/Protein Interactions : CTD5176
Chemical/Pharm GKB GenePA35508
Clinical trialSERPINF1
Cancer Resource (Charite)ENSG00000132386
Ontology : AmiGOserine-type endopeptidase inhibitor activity  extracellular region  extracellular space  multicellular organismal development  cell proliferation  negative regulation of endopeptidase activity  negative regulation of angiogenesis  regulation of proteolysis  extracellular matrix  melanosome  positive regulation of neurogenesis  negative regulation of epithelial cell proliferation involved in prostate gland development  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  extracellular region  extracellular space  multicellular organismal development  cell proliferation  negative regulation of endopeptidase activity  negative regulation of angiogenesis  regulation of proteolysis  extracellular matrix  melanosome  positive regulation of neurogenesis  negative regulation of epithelial cell proliferation involved in prostate gland development  
Other databases
Probes
Litterature
PubMed180 Pubmed reference(s) in Entrez
PubGeneSERPINF1
iHOPSERPINF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Dec 3 19:47:07 CET 2013
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