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SERPINI2 (serpin family I member 2)

Identity

Alias_namesPI14
serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2
serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2
serpin peptidase inhibitor, clade I (pancpin), member 2
Alias_symbol (synonym)PANCPIN
TSA2004
MEPI
pancpin
Other alias
HGNC (Hugo) SERPINI2
LocusID (NCBI) 5276
Atlas_Id 42269
Location 3q26.1  [Link to chromosome band 3q26]
Location_base_pair Starts at 167441789 and ends at 167474132 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MED13L (12q24.21) / SERPINI2 (3q26.1)SERPINI2 (3q26.1) / MED13L (12q24.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SERPINI2   8945
Cards
Entrez_Gene (NCBI)SERPINI2  5276  serpin family I member 2
AliasesMEPI; PANCPIN; PI14; TSA2004
GeneCards (Weizmann)SERPINI2
Ensembl hg19 (Hinxton)ENSG00000114204 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114204 [Gene_View]  chr3:167441789-167474132 [Contig_View]  SERPINI2 [Vega]
ICGC DataPortalENSG00000114204
TCGA cBioPortalSERPINI2
AceView (NCBI)SERPINI2
Genatlas (Paris)SERPINI2
WikiGenes5276
SOURCE (Princeton)SERPINI2
Genetics Home Reference (NIH)SERPINI2
Genomic and cartography
GoldenPath hg38 (UCSC)SERPINI2  -     chr3:167441789-167474132 -  3q26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERPINI2  -     3q26.1   [Description]    (hg19-Feb_2009)
EnsemblSERPINI2 - 3q26.1 [CytoView hg19]  SERPINI2 - 3q26.1 [CytoView hg38]
Mapping of homologs : NCBISERPINI2 [Mapview hg19]  SERPINI2 [Mapview hg38]
OMIM605587   
Gene and transcription
Genbank (Entrez)AB006423 AF130470 AK226025 AK293391 BC027859
RefSeq transcript (Entrez)NM_001012303 NM_006217
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SERPINI2
Cluster EST : UnigeneHs.445555 [ NCBI ]
CGAP (NCI)Hs.445555
Alternative Splicing GalleryENSG00000114204
Gene ExpressionSERPINI2 [ NCBI-GEO ]   SERPINI2 [ EBI - ARRAY_EXPRESS ]   SERPINI2 [ SEEK ]   SERPINI2 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINI2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5276
GTEX Portal (Tissue expression)SERPINI2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75830   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75830  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75830
Splice isoforms : SwissVarO75830
PhosPhoSitePlusO75830
Domaine pattern : Prosite (Expaxy)SERPIN (PS00284)   
Domains : Interpro (EBI)Serpin_CS    Serpin_dom    Serpin_fam   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
Conserved Domain (NCBI)SERPINI2
DMDM Disease mutations5276
Blocks (Seattle)SERPINI2
SuperfamilyO75830
Human Protein AtlasENSG00000114204
Peptide AtlasO75830
HPRD05722
IPIIPI00795490   IPI00944915   IPI00795849   
Protein Interaction databases
DIP (DOE-UCLA)O75830
IntAct (EBI)O75830
FunCoupENSG00000114204
BioGRIDSERPINI2
STRING (EMBL)SERPINI2
ZODIACSERPINI2
Ontologies - Pathways
QuickGOO75830
Ontology : AmiGOserine-type endopeptidase inhibitor activity  protein binding  extracellular space  movement of cell or subcellular component  negative regulation of endopeptidase activity  extracellular exosome  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  protein binding  extracellular space  movement of cell or subcellular component  negative regulation of endopeptidase activity  extracellular exosome  
NDEx NetworkSERPINI2
Atlas of Cancer Signalling NetworkSERPINI2
Wikipedia pathwaysSERPINI2
Orthology - Evolution
OrthoDB5276
GeneTree (enSembl)ENSG00000114204
Phylogenetic Trees/Animal Genes : TreeFamSERPINI2
HOVERGENO75830
HOGENOMO75830
Homologs : HomoloGeneSERPINI2
Homology/Alignments : Family Browser (UCSC)SERPINI2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERPINI2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERPINI2
dbVarSERPINI2
ClinVarSERPINI2
1000_GenomesSERPINI2 
Exome Variant ServerSERPINI2
ExAC (Exome Aggregation Consortium)SERPINI2 (select the gene name)
Genetic variants : HAPMAP5276
Genomic Variants (DGV)SERPINI2 [DGVbeta]
DECIPHERSERPINI2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERPINI2 
Mutations
ICGC Data PortalSERPINI2 
TCGA Data PortalSERPINI2 
Broad Tumor PortalSERPINI2
OASIS PortalSERPINI2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERPINI2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSERPINI2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERPINI2
DgiDB (Drug Gene Interaction Database)SERPINI2
DoCM (Curated mutations)SERPINI2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERPINI2 (select a term)
intoGenSERPINI2
Cancer3DSERPINI2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605587   
Orphanet
MedgenSERPINI2
Genetic Testing Registry SERPINI2
NextProtO75830 [Medical]
TSGene5276
GENETestsSERPINI2
Target ValidationSERPINI2
Huge Navigator SERPINI2 [HugePedia]
snp3D : Map Gene to Disease5276
BioCentury BCIQSERPINI2
ClinGenSERPINI2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5276
Chemical/Pharm GKB GenePA35513
Clinical trialSERPINI2
Miscellaneous
canSAR (ICR)SERPINI2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERPINI2
EVEXSERPINI2
GoPubMedSERPINI2
iHOPSERPINI2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:55:03 CEST 2017

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