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SERTAD2 (SERTA domain containing 2)

Identity

Alias_symbol (synonym)TRIP-Br2
KIAA0127
Sei-2
Other aliasTRIPBR2
HGNC (Hugo) SERTAD2
LocusID (NCBI) 9792
Atlas_Id 51099
Location 2p14  [Link to chromosome band 2p14]
Location_base_pair Starts at 64631621 and ends at 64653912 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SEL1L (14q31.1) / SERTAD2 (2p14)SEL1L 14q31.1 / SERTAD2 2p14

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]

Solid Tumors TT_t0214p14q31ID105025

External links

Nomenclature
HGNC (Hugo)SERTAD2   30784
Cards
Entrez_Gene (NCBI)SERTAD2  9792  SERTA domain containing 2
AliasesSei-2; TRIP-Br2; TRIPBR2
GeneCards (Weizmann)SERTAD2
Ensembl hg19 (Hinxton)ENSG00000179833 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179833 [Gene_View]  ENSG00000179833 [Sequence]  chr2:64631621-64653912 [Contig_View]  SERTAD2 [Vega]
ICGC DataPortalENSG00000179833
TCGA cBioPortalSERTAD2
AceView (NCBI)SERTAD2
Genatlas (Paris)SERTAD2
WikiGenes9792
SOURCE (Princeton)SERTAD2
Genetics Home Reference (NIH)SERTAD2
Genomic and cartography
GoldenPath hg38 (UCSC)SERTAD2  -     chr2:64631621-64653912 -  2p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERTAD2  -     2p14   [Description]    (hg19-Feb_2009)
GoldenPathSERTAD2 - 2p14 [CytoView hg19]  SERTAD2 - 2p14 [CytoView hg38]
ImmunoBaseENSG00000179833
Mapping of homologs : NCBISERTAD2 [Mapview hg19]  SERTAD2 [Mapview hg38]
OMIM617851   
Gene and transcription
Genbank (Entrez)AK124032 AK311117 BC074788 BC074789 BC101639
RefSeq transcript (Entrez)NM_014755
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SERTAD2
Alternative Splicing GalleryENSG00000179833
Gene ExpressionSERTAD2 [ NCBI-GEO ]   SERTAD2 [ EBI - ARRAY_EXPRESS ]   SERTAD2 [ SEEK ]   SERTAD2 [ MEM ]
Gene Expression Viewer (FireBrowse)SERTAD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9792
GTEX Portal (Tissue expression)SERTAD2
Human Protein AtlasENSG00000179833-SERTAD2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14140   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14140  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14140
Splice isoforms : SwissVarQ14140
PhosPhoSitePlusQ14140
Domaine pattern : Prosite (Expaxy)SERTA (PS51053)   
Domains : Interpro (EBI)SERTA_dom   
Domain families : Pfam (Sanger)SERTA (PF06031)   
Domain families : Pfam (NCBI)pfam06031   
Conserved Domain (NCBI)SERTAD2
DMDM Disease mutations9792
Blocks (Seattle)SERTAD2
SuperfamilyQ14140
Human Protein Atlas [tissue]ENSG00000179833-SERTAD2 [tissue]
Peptide AtlasQ14140
HPRD18040
IPIIPI00028974   
Protein Interaction databases
DIP (DOE-UCLA)Q14140
IntAct (EBI)Q14140
FunCoupENSG00000179833
BioGRIDSERTAD2
STRING (EMBL)SERTAD2
ZODIACSERTAD2
Ontologies - Pathways
QuickGOQ14140
Ontology : AmiGOtranscription coactivator activity  nucleus  nucleoplasm  cytoplasm  cytosol  negative regulation of cell growth  positive regulation of transcription, DNA-templated  
Ontology : EGO-EBItranscription coactivator activity  nucleus  nucleoplasm  cytoplasm  cytosol  negative regulation of cell growth  positive regulation of transcription, DNA-templated  
NDEx NetworkSERTAD2
Atlas of Cancer Signalling NetworkSERTAD2
Wikipedia pathwaysSERTAD2
Orthology - Evolution
OrthoDB9792
GeneTree (enSembl)ENSG00000179833
Phylogenetic Trees/Animal Genes : TreeFamSERTAD2
HOGENOMQ14140
Homologs : HomoloGeneSERTAD2
Homology/Alignments : Family Browser (UCSC)SERTAD2
Gene fusions - Rearrangements
Fusion : MitelmanSEL1L/SERTAD2 [14q31.1/2p14]  [t(2;14)(p14;q31)]  
Fusion PortalSEL1L 14q31.1 SERTAD2 2p14 LUAD
Fusion : QuiverSERTAD2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERTAD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERTAD2
dbVarSERTAD2
ClinVarSERTAD2
1000_GenomesSERTAD2 
Exome Variant ServerSERTAD2
ExAC (Exome Aggregation Consortium)ENSG00000179833
GNOMAD BrowserENSG00000179833
Varsome BrowserSERTAD2
Genetic variants : HAPMAP9792
Genomic Variants (DGV)SERTAD2 [DGVbeta]
DECIPHERSERTAD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERTAD2 
Mutations
ICGC Data PortalSERTAD2 
TCGA Data PortalSERTAD2 
Broad Tumor PortalSERTAD2
OASIS PortalSERTAD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERTAD2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSERTAD2
Mutations and Diseases : HGMDSERTAD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERTAD2
DgiDB (Drug Gene Interaction Database)SERTAD2
DoCM (Curated mutations)SERTAD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERTAD2 (select a term)
intoGenSERTAD2
Cancer3DSERTAD2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617851   
Orphanet
DisGeNETSERTAD2
MedgenSERTAD2
Genetic Testing Registry SERTAD2
NextProtQ14140 [Medical]
TSGene9792
GENETestsSERTAD2
Target ValidationSERTAD2
Huge Navigator SERTAD2 [HugePedia]
snp3D : Map Gene to Disease9792
BioCentury BCIQSERTAD2
ClinGenSERTAD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9792
Chemical/Pharm GKB GenePA134948884
Clinical trialSERTAD2
Miscellaneous
canSAR (ICR)SERTAD2 (select the gene name)
HarmonizomeSERTAD2
DataMed IndexSERTAD2
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERTAD2
EVEXSERTAD2
GoPubMedSERTAD2
iHOPSERTAD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Mar 11 19:30:35 CET 2020
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