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SESN3 (sestrin 3)

Identity

Alias_symbol (synonym)SEST3
MGC29667
Other alias
HGNC (Hugo) SESN3
LocusID (NCBI) 143686
Atlas_Id 56562
Location 11q21  [Link to chromosome band 11q21]
Location_base_pair Starts at 94898677 and ends at 94965705 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SESN3   23060
Cards
Entrez_Gene (NCBI)SESN3  143686  sestrin 3
AliasesSEST3
GeneCards (Weizmann)SESN3
Ensembl hg19 (Hinxton)ENSG00000149212 [Gene_View]  chr11:94898677-94965705 [Contig_View]  SESN3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000149212 [Gene_View]  chr11:94898677-94965705 [Contig_View]  SESN3 [Vega]
ICGC DataPortalENSG00000149212
TCGA cBioPortalSESN3
AceView (NCBI)SESN3
Genatlas (Paris)SESN3
WikiGenes143686
SOURCE (Princeton)SESN3
Genetics Home Reference (NIH)SESN3
Genomic and cartography
GoldenPath hg19 (UCSC)SESN3  -     chr11:94898677-94965705 -  11q21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SESN3  -     11q21   [Description]    (hg38-Dec_2013)
EnsemblSESN3 - 11q21 [CytoView hg19]  SESN3 - 11q21 [CytoView hg38]
Mapping of homologs : NCBISESN3 [Mapview hg19]  SESN3 [Mapview hg38]
OMIM607768   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001271594 NM_144665
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SESN3
Cluster EST : UnigeneHs.120633 [ NCBI ]
CGAP (NCI)Hs.120633
Alternative Splicing GalleryENSG00000149212
Gene ExpressionSESN3 [ NCBI-GEO ]   SESN3 [ EBI - ARRAY_EXPRESS ]   SESN3 [ SEEK ]   SESN3 [ MEM ]
Gene Expression Viewer (FireBrowse)SESN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)143686
GTEX Portal (Tissue expression)SESN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP58005   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP58005  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP58005
Splice isoforms : SwissVarP58005
PhosPhoSitePlusP58005
Domains : Interpro (EBI)AhpD-like    Sestrin   
Domain families : Pfam (Sanger)PA26 (PF04636)   
Domain families : Pfam (NCBI)pfam04636   
Conserved Domain (NCBI)SESN3
DMDM Disease mutations143686
Blocks (Seattle)SESN3
SuperfamilyP58005
Human Protein AtlasENSG00000149212
Peptide AtlasP58005
HPRD09682
IPIIPI00010540   IPI00220657   IPI00220658   IPI00922600   
Protein Interaction databases
DIP (DOE-UCLA)P58005
IntAct (EBI)P58005
FunCoupENSG00000149212
BioGRIDSESN3
STRING (EMBL)SESN3
ZODIACSESN3
Ontologies - Pathways
QuickGOP58005
Ontology : AmiGOnucleus  cytoplasm  oxidoreductase activity  response to insulin  glucose homeostasis  regulation of protein kinase B signaling  oxidation-reduction process  GATOR2 complex  cellular response to amino acid stimulus  regulation of response to reactive oxygen species  negative regulation of TORC1 signaling  
Ontology : EGO-EBInucleus  cytoplasm  oxidoreductase activity  response to insulin  glucose homeostasis  regulation of protein kinase B signaling  oxidation-reduction process  GATOR2 complex  cellular response to amino acid stimulus  regulation of response to reactive oxygen species  negative regulation of TORC1 signaling  
Pathways : KEGGp53 signaling pathway   
NDEx NetworkSESN3
Atlas of Cancer Signalling NetworkSESN3
Wikipedia pathwaysSESN3
Orthology - Evolution
OrthoDB143686
GeneTree (enSembl)ENSG00000149212
Phylogenetic Trees/Animal Genes : TreeFamSESN3
HOVERGENP58005
HOGENOMP58005
Homologs : HomoloGeneSESN3
Homology/Alignments : Family Browser (UCSC)SESN3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSESN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SESN3
dbVarSESN3
ClinVarSESN3
1000_GenomesSESN3 
Exome Variant ServerSESN3
ExAC (Exome Aggregation Consortium)SESN3 (select the gene name)
Genetic variants : HAPMAP143686
Genomic Variants (DGV)SESN3 [DGVbeta]
DECIPHER (Syndromes)11:94898677-94965705  ENSG00000149212
CONAN: Copy Number AnalysisSESN3 
Mutations
ICGC Data PortalSESN3 
TCGA Data PortalSESN3 
Broad Tumor PortalSESN3
OASIS PortalSESN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSESN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSESN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SESN3
DgiDB (Drug Gene Interaction Database)SESN3
DoCM (Curated mutations)SESN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SESN3 (select a term)
intoGenSESN3
Cancer3DSESN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607768   
Orphanet
MedgenSESN3
Genetic Testing Registry SESN3
NextProtP58005 [Medical]
TSGene143686
GENETestsSESN3
Huge Navigator SESN3 [HugePedia]
snp3D : Map Gene to Disease143686
BioCentury BCIQSESN3
ClinGenSESN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD143686
Chemical/Pharm GKB GenePA134914983
Clinical trialSESN3
Miscellaneous
canSAR (ICR)SESN3 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSESN3
EVEXSESN3
GoPubMedSESN3
iHOPSESN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:18:57 CEST 2017

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