SESTD1 (SEC14 and spectrin domain containing 1)

2006-10-01  

Identity

HGNC
LOCATION
2q31.2
LOCUSID
ALIAS
SOLO
FUSION GENES

Other Information

Locus ID:

NCBI: 91404
HGNC: 18379
Ensembl: ENSG00000187231

Variants:

dbSNP: 91404
ClinVar: 91404
TCGA: ENSG00000187231
COSMIC: SESTD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187231ENST00000335289H7BXT9
ENSG00000187231ENST00000426988H7BZR8
ENSG00000187231ENST00000428443Q86VW0
ENSG00000187231ENST00000435047C9J4X8
ENSG00000187231ENST00000440010C9JHW6
ENSG00000187231ENST00000446758H0Y774
ENSG00000187231ENST00000452991F8WFB2

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
201641952010The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.23
266767842015Human MicroRNA miR-532-5p Exhibits Antiviral Activity against West Nile Virus via Suppression of Host Genes SESTD1 and TAB3 Required for Virus Replication.22
268230192016Interplay between Solo and keratin filaments is crucial for mechanical force-induced stress fiber reinforcement.9
296726032018Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells.1

Citation

Dessen P

SESTD1 (SEC14 and spectrin domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43488/sestd1