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SETD3 (SET domain containing 3)

Identity

Alias_namesC14orf154
chromosome 14 open reading frame 154
Alias_symbol (synonym)FLJ23027
Other alias
HGNC (Hugo) SETD3
LocusID (NCBI) 84193
Atlas_Id 54611
Location 14q32.2  [Link to chromosome band 14q32]
Location_base_pair Starts at 99397746 and ends at 99480889 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC85C (14q32.2) / SETD3 (14q32.2)EIF3CL (16p11.2) / SETD3 (14q32.2)SETD3 (14q32.2) / SETD3 (14q32.2)
YES1 (18p11.32) / SETD3 (14q32.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SETD3   20493
Cards
Entrez_Gene (NCBI)SETD3  84193  SET domain containing 3
AliasesC14orf154
GeneCards (Weizmann)SETD3
Ensembl hg19 (Hinxton)ENSG00000183576 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183576 [Gene_View]  chr14:99397746-99480889 [Contig_View]  SETD3 [Vega]
ICGC DataPortalENSG00000183576
TCGA cBioPortalSETD3
AceView (NCBI)SETD3
Genatlas (Paris)SETD3
WikiGenes84193
SOURCE (Princeton)SETD3
Genetics Home Reference (NIH)SETD3
Genomic and cartography
GoldenPath hg38 (UCSC)SETD3  -     chr14:99397746-99480889 -  14q32.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SETD3  -     14q32.2   [Description]    (hg19-Feb_2009)
EnsemblSETD3 - 14q32.2 [CytoView hg19]  SETD3 - 14q32.2 [CytoView hg38]
Mapping of homologs : NCBISETD3 [Mapview hg19]  SETD3 [Mapview hg38]
OMIM615671   
Gene and transcription
Genbank (Entrez)AK026680 AK302882 AL359581 BC009054 BC037395
RefSeq transcript (Entrez)NM_032233 NM_199123
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SETD3
Cluster EST : UnigeneHs.510407 [ NCBI ]
CGAP (NCI)Hs.510407
Alternative Splicing GalleryENSG00000183576
Gene ExpressionSETD3 [ NCBI-GEO ]   SETD3 [ EBI - ARRAY_EXPRESS ]   SETD3 [ SEEK ]   SETD3 [ MEM ]
Gene Expression Viewer (FireBrowse)SETD3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84193
GTEX Portal (Tissue expression)SETD3
Human Protein AtlasENSG00000183576-SETD3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86TU7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86TU7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86TU7
Splice isoforms : SwissVarQ86TU7
PhosPhoSitePlusQ86TU7
Domaine pattern : Prosite (Expaxy)SAM_MT43_SETD3 (PS51565)    SET (PS50280)   
Domains : Interpro (EBI)Hist-Lys_N-MeTrfase_SETD3    Rubisco_LSMT_subst-bd    SET_dom   
Domain families : Pfam (Sanger)Rubis-subs-bind (PF09273)    SET (PF00856)   
Domain families : Pfam (NCBI)pfam09273    pfam00856   
Conserved Domain (NCBI)SETD3
DMDM Disease mutations84193
Blocks (Seattle)SETD3
PDB (SRS)3SMT   
PDB (PDBSum)3SMT   
PDB (IMB)3SMT   
PDB (RSDB)3SMT   
Structural Biology KnowledgeBase3SMT   
SCOP (Structural Classification of Proteins)3SMT   
CATH (Classification of proteins structures)3SMT   
SuperfamilyQ86TU7
Human Protein Atlas [tissue]ENSG00000183576-SETD3 [tissue]
Peptide AtlasQ86TU7
HPRD08664
IPIIPI00165026   IPI00395872   IPI00658081   IPI00878625   
Protein Interaction databases
DIP (DOE-UCLA)Q86TU7
IntAct (EBI)Q86TU7
FunCoupENSG00000183576
BioGRIDSETD3
STRING (EMBL)SETD3
ZODIACSETD3
Ontologies - Pathways
QuickGOQ86TU7
Ontology : AmiGOnuclear chromatin  RNA polymerase II activating transcription factor binding  transcription coactivator activity  transcription coactivator activity  nucleoplasm  transcription, DNA-templated  histone H3-K36 methylation  histone H3-K36 methylation  peptidyl-lysine trimethylation  peptidyl-lysine trimethylation  histone-lysine N-methyltransferase activity  peptidyl-lysine monomethylation  peptidyl-lysine monomethylation  peptidyl-lysine dimethylation  peptidyl-lysine dimethylation  histone methyltransferase activity (H3-K4 specific)  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  histone methyltransferase activity (H3-K36 specific)  histone methyltransferase activity (H3-K36 specific)  positive regulation of muscle cell differentiation  histone H3-K4 methylation  
Ontology : EGO-EBInuclear chromatin  RNA polymerase II activating transcription factor binding  transcription coactivator activity  transcription coactivator activity  nucleoplasm  transcription, DNA-templated  histone H3-K36 methylation  histone H3-K36 methylation  peptidyl-lysine trimethylation  peptidyl-lysine trimethylation  histone-lysine N-methyltransferase activity  peptidyl-lysine monomethylation  peptidyl-lysine monomethylation  peptidyl-lysine dimethylation  peptidyl-lysine dimethylation  histone methyltransferase activity (H3-K4 specific)  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  histone methyltransferase activity (H3-K36 specific)  histone methyltransferase activity (H3-K36 specific)  positive regulation of muscle cell differentiation  histone H3-K4 methylation  
NDEx NetworkSETD3
Atlas of Cancer Signalling NetworkSETD3
Wikipedia pathwaysSETD3
Orthology - Evolution
OrthoDB84193
GeneTree (enSembl)ENSG00000183576
Phylogenetic Trees/Animal Genes : TreeFamSETD3
HOVERGENQ86TU7
HOGENOMQ86TU7
Homologs : HomoloGeneSETD3
Homology/Alignments : Family Browser (UCSC)SETD3
Gene fusions - Rearrangements
Fusion : MitelmanCCDC85C/SETD3 [14q32.2/14q32.2]  [t(14;14)(q32;q32)]  
Tumor Fusion PortalSETD3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSETD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SETD3
dbVarSETD3
ClinVarSETD3
1000_GenomesSETD3 
Exome Variant ServerSETD3
ExAC (Exome Aggregation Consortium)ENSG00000183576
GNOMAD BrowserENSG00000183576
Genetic variants : HAPMAP84193
Genomic Variants (DGV)SETD3 [DGVbeta]
DECIPHERSETD3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSETD3 
Mutations
ICGC Data PortalSETD3 
TCGA Data PortalSETD3 
Broad Tumor PortalSETD3
OASIS PortalSETD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSETD3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSETD3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SETD3
DgiDB (Drug Gene Interaction Database)SETD3
DoCM (Curated mutations)SETD3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SETD3 (select a term)
intoGenSETD3
Cancer3DSETD3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615671   
Orphanet
DisGeNETSETD3
MedgenSETD3
Genetic Testing Registry SETD3
NextProtQ86TU7 [Medical]
TSGene84193
GENETestsSETD3
Target ValidationSETD3
Huge Navigator SETD3 [HugePedia]
snp3D : Map Gene to Disease84193
BioCentury BCIQSETD3
ClinGenSETD3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84193
Chemical/Pharm GKB GenePA134883013
Clinical trialSETD3
Miscellaneous
canSAR (ICR)SETD3 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSETD3
EVEXSETD3
GoPubMedSETD3
iHOPSETD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:34:13 CET 2017

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