SETD4 (SET domain containing 4)

2014-11-01  

Identity

HGNC
SETD4
LOCATION
21q22.12
LOCUSID
54093
ALIAS
C21orf18,C21orf27
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54093
HGNC: 1258
Ensembl: ENSG00000185917

Variants:

dbSNP: 54093
ClinVar: 54093
TCGA: ENSG00000185917
COSMIC: SETD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185917ENST00000332131Q9NVD3
ENSG00000185917ENST00000399201A8MTS1
ENSG00000185917ENST00000399205A8MTS1
ENSG00000185917ENST00000399207Q9NVD3
ENSG00000185917ENST00000399208Q9NVD3
ENSG00000185917ENST00000399212Q9NVD3
ENSG00000185917ENST00000399215Q9NVD3
ENSG00000185917ENST00000424303C9JWV5
ENSG00000185917ENST00000429161C9JIU9
ENSG00000185917ENST00000442559C9JPA1
ENSG00000185917ENST00000443703C9J256
ENSG00000185917ENST00000446166C9JYV0

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA449212daunorubicinChemicalVariantAnnotationassociatedPK19204081
PA449412doxorubicinChemicalVariantAnnotationassociatedPK19204081

References

Pubmed IDYearTitleCitations
313080462019SET Domain-Containing Protein 4 Epigenetically Controls Breast Cancer Stem Cell Quiescence.4

Citation

Dessen P

SETD4 (SET domain containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73155/setd4