Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SETD7 (SET domain containing lysine methyltransferase 7)

Identity

Alias_symbol (synonym)KIAA1717
SET7
SET7/9
Set9
KMT7
Other aliasSET9
HGNC (Hugo) SETD7
LocusID (NCBI) 80854
Atlas_Id 50018
Location 4q31.1  [Link to chromosome band 4q31]
Location_base_pair Starts at 139495935 and ends at 139556769 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SETD7 (4q31.1) / FBN1 (15q21.1)SETD7 (4q31.1) / SETD7 (4q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SETD7   30412
Cards
Entrez_Gene (NCBI)SETD7  80854  SET domain containing lysine methyltransferase 7
AliasesKMT7; SET7; SET7/9; SET9
GeneCards (Weizmann)SETD7
Ensembl hg19 (Hinxton)ENSG00000145391 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145391 [Gene_View]  chr4:139495935-139556769 [Contig_View]  SETD7 [Vega]
ICGC DataPortalENSG00000145391
TCGA cBioPortalSETD7
AceView (NCBI)SETD7
Genatlas (Paris)SETD7
WikiGenes80854
SOURCE (Princeton)SETD7
Genetics Home Reference (NIH)SETD7
Genomic and cartography
GoldenPath hg38 (UCSC)SETD7  -     chr4:139495935-139556769 -  4q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SETD7  -     4q31.1   [Description]    (hg19-Feb_2009)
EnsemblSETD7 - 4q31.1 [CytoView hg19]  SETD7 - 4q31.1 [CytoView hg38]
Mapping of homologs : NCBISETD7 [Mapview hg19]  SETD7 [Mapview hg38]
OMIM606594   
Gene and transcription
Genbank (Entrez)AB051504 AF448510 AF462150 AI985614 AK024846
RefSeq transcript (Entrez)NM_001306199 NM_001306200 NM_030648
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SETD7
Cluster EST : UnigeneHs.480792 [ NCBI ]
CGAP (NCI)Hs.480792
Alternative Splicing GalleryENSG00000145391
Gene ExpressionSETD7 [ NCBI-GEO ]   SETD7 [ EBI - ARRAY_EXPRESS ]   SETD7 [ SEEK ]   SETD7 [ MEM ]
Gene Expression Viewer (FireBrowse)SETD7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80854
GTEX Portal (Tissue expression)SETD7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WTS6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WTS6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WTS6
Splice isoforms : SwissVarQ8WTS6
Catalytic activity : Enzyme2.1.1.43 [ Enzyme-Expasy ]   2.1.1.432.1.1.43 [ IntEnz-EBI ]   2.1.1.43 [ BRENDA ]   2.1.1.43 [ KEGG ]   
PhosPhoSitePlusQ8WTS6
Domaine pattern : Prosite (Expaxy)SAM_MT43_SET7 (PS51577)    SET (PS50280)   
Domains : Interpro (EBI)Hist-Lys_N-MeTrfase_SET    MORN    SET_dom   
Domain families : Pfam (Sanger)MORN (PF02493)    SET (PF00856)   
Domain families : Pfam (NCBI)pfam02493    pfam00856   
Domain families : Smart (EMBL)SET (SM00317)  
Conserved Domain (NCBI)SETD7
DMDM Disease mutations80854
Blocks (Seattle)SETD7
PDB (SRS)1H3I    1MT6    1MUF    1N6A    1N6C    1O9S    1XQH    2F69    3CBM    3CBO    3CBP    3M53    3M54    3M55    3M56    3M57    3M58    3M59    3M5A    3OS5    3VUZ    3VV0    4E47    4J7F    4J7I    4J83    4J8O    4JDS    4JLG    5AYF    5EG2   
PDB (PDBSum)1H3I    1MT6    1MUF    1N6A    1N6C    1O9S    1XQH    2F69    3CBM    3CBO    3CBP    3M53    3M54    3M55    3M56    3M57    3M58    3M59    3M5A    3OS5    3VUZ    3VV0    4E47    4J7F    4J7I    4J83    4J8O    4JDS    4JLG    5AYF    5EG2   
PDB (IMB)1H3I    1MT6    1MUF    1N6A    1N6C    1O9S    1XQH    2F69    3CBM    3CBO    3CBP    3M53    3M54    3M55    3M56    3M57    3M58    3M59    3M5A    3OS5    3VUZ    3VV0    4E47    4J7F    4J7I    4J83    4J8O    4JDS    4JLG    5AYF    5EG2   
PDB (RSDB)1H3I    1MT6    1MUF    1N6A    1N6C    1O9S    1XQH    2F69    3CBM    3CBO    3CBP    3M53    3M54    3M55    3M56    3M57    3M58    3M59    3M5A    3OS5    3VUZ    3VV0    4E47    4J7F    4J7I    4J83    4J8O    4JDS    4JLG    5AYF    5EG2   
Structural Biology KnowledgeBase1H3I    1MT6    1MUF    1N6A    1N6C    1O9S    1XQH    2F69    3CBM    3CBO    3CBP    3M53    3M54    3M55    3M56    3M57    3M58    3M59    3M5A    3OS5    3VUZ    3VV0    4E47    4J7F    4J7I    4J83    4J8O    4JDS    4JLG    5AYF    5EG2   
SCOP (Structural Classification of Proteins)1H3I    1MT6    1MUF    1N6A    1N6C    1O9S    1XQH    2F69    3CBM    3CBO    3CBP    3M53    3M54    3M55    3M56    3M57    3M58    3M59    3M5A    3OS5    3VUZ    3VV0    4E47    4J7F    4J7I    4J83    4J8O    4JDS    4JLG    5AYF    5EG2   
CATH (Classification of proteins structures)1H3I    1MT6    1MUF    1N6A    1N6C    1O9S    1XQH    2F69    3CBM    3CBO    3CBP    3M53    3M54    3M55    3M56    3M57    3M58    3M59    3M5A    3OS5    3VUZ    3VV0    4E47    4J7F    4J7I    4J83    4J8O    4JDS    4JLG    5AYF    5EG2   
SuperfamilyQ8WTS6
Human Protein AtlasENSG00000145391
Peptide AtlasQ8WTS6
HPRD16226
IPIIPI00028366   IPI00879341   IPI00879517   IPI00967470   
Protein Interaction databases
DIP (DOE-UCLA)Q8WTS6
IntAct (EBI)Q8WTS6
FunCoupENSG00000145391
BioGRIDSETD7
STRING (EMBL)SETD7
ZODIACSETD7
Ontologies - Pathways
QuickGOQ8WTS6
Ontology : AmiGOp53 binding  chromatin binding  protein binding  nucleoplasm  chromosome  nucleolus  chromatin organization  transcription, DNA-templated  cellular response to DNA damage stimulus  protein-lysine N-methyltransferase activity  histone-lysine N-methyltransferase activity  histone-lysine N-methyltransferase activity  histone-lysine N-methyltransferase activity  peptidyl-lysine monomethylation  peptidyl-lysine dimethylation  histone lysine methylation  response to ethanol  positive regulation of transcription, DNA-templated  regulation of histone H3-K9 methylation  heterochromatin organization  
Ontology : EGO-EBIp53 binding  chromatin binding  protein binding  nucleoplasm  chromosome  nucleolus  chromatin organization  transcription, DNA-templated  cellular response to DNA damage stimulus  protein-lysine N-methyltransferase activity  histone-lysine N-methyltransferase activity  histone-lysine N-methyltransferase activity  histone-lysine N-methyltransferase activity  peptidyl-lysine monomethylation  peptidyl-lysine dimethylation  histone lysine methylation  response to ethanol  positive regulation of transcription, DNA-templated  regulation of histone H3-K9 methylation  heterochromatin organization  
Pathways : KEGGLysine degradation    FoxO signaling pathway   
NDEx NetworkSETD7
Atlas of Cancer Signalling NetworkSETD7
Wikipedia pathwaysSETD7
Orthology - Evolution
OrthoDB80854
GeneTree (enSembl)ENSG00000145391
Phylogenetic Trees/Animal Genes : TreeFamSETD7
HOVERGENQ8WTS6
HOGENOMQ8WTS6
Homologs : HomoloGeneSETD7
Homology/Alignments : Family Browser (UCSC)SETD7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSETD7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SETD7
dbVarSETD7
ClinVarSETD7
1000_GenomesSETD7 
Exome Variant ServerSETD7
ExAC (Exome Aggregation Consortium)SETD7 (select the gene name)
Genetic variants : HAPMAP80854
Genomic Variants (DGV)SETD7 [DGVbeta]
DECIPHERSETD7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSETD7 
Mutations
ICGC Data PortalSETD7 
TCGA Data PortalSETD7 
Broad Tumor PortalSETD7
OASIS PortalSETD7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSETD7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSETD7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SETD7
DgiDB (Drug Gene Interaction Database)SETD7
DoCM (Curated mutations)SETD7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SETD7 (select a term)
intoGenSETD7
Cancer3DSETD7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606594   
Orphanet
MedgenSETD7
Genetic Testing Registry SETD7
NextProtQ8WTS6 [Medical]
TSGene80854
GENETestsSETD7
Huge Navigator SETD7 [HugePedia]
snp3D : Map Gene to Disease80854
BioCentury BCIQSETD7
ClinGenSETD7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80854
Chemical/Pharm GKB GenePA143485615
Clinical trialSETD7
Miscellaneous
canSAR (ICR)SETD7 (select the gene name)
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSETD7
EVEXSETD7
GoPubMedSETD7
iHOPSETD7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:36:48 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.