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SETDB2 (SET domain bifurcated 2)

Identity

Alias_namesC13orf4
chromosome 13 open reading frame 4
SET domain, bifurcated 2
Alias_symbol (synonym)CLLD8
CLLL8
KMT1F
Other alias
HGNC (Hugo) SETDB2
LocusID (NCBI) 83852
Atlas_Id 73159
Location 13q14.2  [Link to chromosome band 13q14]
Location_base_pair Starts at 49444293 and ends at 49495003 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SETDB2 (13q14.2) / ERH (14q24.1)SETDB2 (13q14.2) / STEAP2 (7q21.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SETDB2   20263
Cards
Entrez_Gene (NCBI)SETDB2  83852  SET domain bifurcated 2
AliasesC13orf4; CLLD8; CLLL8; KMT1F
GeneCards (Weizmann)SETDB2
Ensembl hg19 (Hinxton)ENSG00000136169 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136169 [Gene_View]  chr13:49444293-49495003 [Contig_View]  SETDB2 [Vega]
ICGC DataPortalENSG00000136169
TCGA cBioPortalSETDB2
AceView (NCBI)SETDB2
Genatlas (Paris)SETDB2
WikiGenes83852
SOURCE (Princeton)SETDB2
Genetics Home Reference (NIH)SETDB2
Genomic and cartography
GoldenPath hg38 (UCSC)SETDB2  -     chr13:49444293-49495003 +  13q14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SETDB2  -     13q14.2   [Description]    (hg19-Feb_2009)
EnsemblSETDB2 - 13q14.2 [CytoView hg19]  SETDB2 - 13q14.2 [CytoView hg38]
Mapping of homologs : NCBISETDB2 [Mapview hg19]  SETDB2 [Mapview hg38]
OMIM607865   
Gene and transcription
Genbank (Entrez)AB209349 AF086317 AF277186 AF334407 AK307593
RefSeq transcript (Entrez)NM_001160308 NM_001320699 NM_031915
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SETDB2
Cluster EST : UnigeneHs.631789 [ NCBI ]
CGAP (NCI)Hs.631789
Alternative Splicing GalleryENSG00000136169
Gene ExpressionSETDB2 [ NCBI-GEO ]   SETDB2 [ EBI - ARRAY_EXPRESS ]   SETDB2 [ SEEK ]   SETDB2 [ MEM ]
Gene Expression Viewer (FireBrowse)SETDB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83852
GTEX Portal (Tissue expression)SETDB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96T68   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96T68  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96T68
Splice isoforms : SwissVarQ96T68
Catalytic activity : Enzyme2.1.1.43 [ Enzyme-Expasy ]   2.1.1.432.1.1.43 [ IntEnz-EBI ]   2.1.1.43 [ BRENDA ]   2.1.1.43 [ KEGG ]   
PhosPhoSitePlusQ96T68
Domaine pattern : Prosite (Expaxy)MBD (PS50982)    PRE_SET (PS50867)    SET (PS50280)   
Domains : Interpro (EBI)DNA-bd_dom    Methyl_CpG_DNA-bd    Pre-SET_dom    SET_dom   
Domain families : Pfam (Sanger)MBD (PF01429)    Pre-SET (PF05033)    SET (PF00856)   
Domain families : Pfam (NCBI)pfam01429    pfam05033    pfam00856   
Domain families : Smart (EMBL)MBD (SM00391)  PreSET (SM00468)  SET (SM00317)  
Conserved Domain (NCBI)SETDB2
DMDM Disease mutations83852
Blocks (Seattle)SETDB2
SuperfamilyQ96T68
Human Protein AtlasENSG00000136169
Peptide AtlasQ96T68
HPRD09712
IPIIPI00045922   IPI00375872   IPI00843770   IPI00555842   
Protein Interaction databases
DIP (DOE-UCLA)Q96T68
IntAct (EBI)Q96T68
FunCoupENSG00000136169
BioGRIDSETDB2
STRING (EMBL)SETDB2
ZODIACSETDB2
Ontologies - Pathways
QuickGOQ96T68
Ontology : AmiGOmitotic cell cycle  heart looping  DNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  chromosome segregation  zinc ion binding  histone-lysine N-methyltransferase activity  negative regulation of transcription, DNA-templated  histone methyltransferase activity (H3-K9 specific)  cell division  histone H3-K9 methylation  left/right axis specification  
Ontology : EGO-EBImitotic cell cycle  heart looping  DNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  chromosome segregation  zinc ion binding  histone-lysine N-methyltransferase activity  negative regulation of transcription, DNA-templated  histone methyltransferase activity (H3-K9 specific)  cell division  histone H3-K9 methylation  left/right axis specification  
Pathways : KEGGLysine degradation   
NDEx NetworkSETDB2
Atlas of Cancer Signalling NetworkSETDB2
Wikipedia pathwaysSETDB2
Orthology - Evolution
OrthoDB83852
GeneTree (enSembl)ENSG00000136169
Phylogenetic Trees/Animal Genes : TreeFamSETDB2
HOVERGENQ96T68
HOGENOMQ96T68
Homologs : HomoloGeneSETDB2
Homology/Alignments : Family Browser (UCSC)SETDB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSETDB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SETDB2
dbVarSETDB2
ClinVarSETDB2
1000_GenomesSETDB2 
Exome Variant ServerSETDB2
ExAC (Exome Aggregation Consortium)SETDB2 (select the gene name)
Genetic variants : HAPMAP83852
Genomic Variants (DGV)SETDB2 [DGVbeta]
DECIPHERSETDB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSETDB2 
Mutations
ICGC Data PortalSETDB2 
TCGA Data PortalSETDB2 
Broad Tumor PortalSETDB2
OASIS PortalSETDB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSETDB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSETDB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SETDB2
DgiDB (Drug Gene Interaction Database)SETDB2
DoCM (Curated mutations)SETDB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SETDB2 (select a term)
intoGenSETDB2
Cancer3DSETDB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607865   
Orphanet
MedgenSETDB2
Genetic Testing Registry SETDB2
NextProtQ96T68 [Medical]
TSGene83852
GENETestsSETDB2
Target ValidationSETDB2
Huge Navigator SETDB2 [HugePedia]
snp3D : Map Gene to Disease83852
BioCentury BCIQSETDB2
ClinGenSETDB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83852
Chemical/Pharm GKB GenePA134956285
Clinical trialSETDB2
Miscellaneous
canSAR (ICR)SETDB2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSETDB2
EVEXSETDB2
GoPubMedSETDB2
iHOPSETDB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:40:29 CEST 2017

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