Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SETMAR (SET domain and mariner transposase fusion gene)

Identity

Alias_symbol (synonym)metnase
Other aliasMETNASE
Mar1
HGNC (Hugo) SETMAR
LocusID (NCBI) 6419
Atlas_Id 43714
Location 3p26.1  [Link to chromosome band 3p26]
Location_base_pair Starts at 4303304 and ends at 4317265 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ITPR1 (3p26.1) / SETMAR (3p26.1)KSR2 (12q24.22) / SETMAR (3p26.1)ITPR1 3p26.1 / SETMAR 3p26.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SETMAR   10762
Cards
Entrez_Gene (NCBI)SETMAR  6419  SET domain and mariner transposase fusion gene
AliasesMETNASE; Mar1
GeneCards (Weizmann)SETMAR
Ensembl hg19 (Hinxton)ENSG00000170364 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170364 [Gene_View]  chr3:4303304-4317265 [Contig_View]  SETMAR [Vega]
ICGC DataPortalENSG00000170364
TCGA cBioPortalSETMAR
AceView (NCBI)SETMAR
Genatlas (Paris)SETMAR
WikiGenes6419
SOURCE (Princeton)SETMAR
Genetics Home Reference (NIH)SETMAR
Genomic and cartography
GoldenPath hg38 (UCSC)SETMAR  -     chr3:4303304-4317265 +  3p26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SETMAR  -     3p26.1   [Description]    (hg19-Feb_2009)
EnsemblSETMAR - 3p26.1 [CytoView hg19]  SETMAR - 3p26.1 [CytoView hg38]
Mapping of homologs : NCBISETMAR [Mapview hg19]  SETMAR [Mapview hg38]
OMIM609834   
Gene and transcription
Genbank (Entrez)AF054989 AK122967 AK222734 AK297865 AK302296
RefSeq transcript (Entrez)NM_001243723 NM_001276325 NM_001320676 NM_001320677 NM_001320678 NM_006515
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SETMAR
Cluster EST : UnigeneHs.475300 [ NCBI ]
CGAP (NCI)Hs.475300
Alternative Splicing GalleryENSG00000170364
Gene ExpressionSETMAR [ NCBI-GEO ]   SETMAR [ EBI - ARRAY_EXPRESS ]   SETMAR [ SEEK ]   SETMAR [ MEM ]
Gene Expression Viewer (FireBrowse)SETMAR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6419
GTEX Portal (Tissue expression)SETMAR
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53H47   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53H47  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53H47
Splice isoforms : SwissVarQ53H47
PhosPhoSitePlusQ53H47
Domaine pattern : Prosite (Expaxy)POST_SET (PS50868)    PRE_SET (PS50867)    SET (PS50280)   
Domains : Interpro (EBI)Post-SET_dom    Pre-SET_dom    SET_dom    Transposase_1   
Domain families : Pfam (Sanger)Pre-SET (PF05033)    SET (PF00856)    Transposase_1 (PF01359)   
Domain families : Pfam (NCBI)pfam05033    pfam00856    pfam01359   
Domain families : Smart (EMBL)PreSET (SM00468)  SET (SM00317)  
Conserved Domain (NCBI)SETMAR
DMDM Disease mutations6419
Blocks (Seattle)SETMAR
PDB (SRS)3BO5    3F2K    3K9J    3K9K   
PDB (PDBSum)3BO5    3F2K    3K9J    3K9K   
PDB (IMB)3BO5    3F2K    3K9J    3K9K   
PDB (RSDB)3BO5    3F2K    3K9J    3K9K   
Structural Biology KnowledgeBase3BO5    3F2K    3K9J    3K9K   
SCOP (Structural Classification of Proteins)3BO5    3F2K    3K9J    3K9K   
CATH (Classification of proteins structures)3BO5    3F2K    3K9J    3K9K   
SuperfamilyQ53H47
Human Protein AtlasENSG00000170364
Peptide AtlasQ53H47
HPRD10225
IPIIPI00784520   IPI00171821   IPI00879669   IPI00879826   IPI00878033   IPI00925410   IPI00925837   
Protein Interaction databases
DIP (DOE-UCLA)Q53H47
IntAct (EBI)Q53H47
FunCoupENSG00000170364
BioGRIDSETMAR
STRING (EMBL)SETMAR
ZODIACSETMAR
Ontologies - Pathways
QuickGOQ53H47
Ontology : AmiGOsingle-stranded DNA endodeoxyribonuclease activity  DNA double-strand break processing  DNA catabolic process, endonucleolytic  DNA catabolic process, endonucleolytic  condensed chromosome  DNA binding  DNA binding  double-stranded DNA binding  single-stranded DNA binding  endonuclease activity  endonuclease activity  protein binding  nucleus  nucleus  nucleolus  double-strand break repair via nonhomologous end joining  double-strand break repair via nonhomologous end joining  zinc ion binding  cell proliferation  histone H3-K36 methylation  histone H3-K36 methylation  DNA integration  replication fork processing  site of double-strand break  site of double-strand break  histone methyltransferase activity (H3-K4 specific)  protein homodimerization activity  DNA topoisomerase binding  mitotic DNA integrity checkpoint  histone methyltransferase activity (H3-K36 specific)  histone H3-K4 methylation  negative regulation of cell cycle arrest  nucleic acid phosphodiester bond hydrolysis  histone H3-K36 dimethylation  positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity  positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity  positive regulation of double-strand break repair via nonhomologous end joining  negative regulation of chromosome organization  
Ontology : EGO-EBIsingle-stranded DNA endodeoxyribonuclease activity  DNA double-strand break processing  DNA catabolic process, endonucleolytic  DNA catabolic process, endonucleolytic  condensed chromosome  DNA binding  DNA binding  double-stranded DNA binding  single-stranded DNA binding  endonuclease activity  endonuclease activity  protein binding  nucleus  nucleus  nucleolus  double-strand break repair via nonhomologous end joining  double-strand break repair via nonhomologous end joining  zinc ion binding  cell proliferation  histone H3-K36 methylation  histone H3-K36 methylation  DNA integration  replication fork processing  site of double-strand break  site of double-strand break  histone methyltransferase activity (H3-K4 specific)  protein homodimerization activity  DNA topoisomerase binding  mitotic DNA integrity checkpoint  histone methyltransferase activity (H3-K36 specific)  histone H3-K4 methylation  negative regulation of cell cycle arrest  nucleic acid phosphodiester bond hydrolysis  histone H3-K36 dimethylation  positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity  positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity  positive regulation of double-strand break repair via nonhomologous end joining  negative regulation of chromosome organization  
Pathways : KEGGLysine degradation   
NDEx NetworkSETMAR
Atlas of Cancer Signalling NetworkSETMAR
Wikipedia pathwaysSETMAR
Orthology - Evolution
OrthoDB6419
GeneTree (enSembl)ENSG00000170364
Phylogenetic Trees/Animal Genes : TreeFamSETMAR
HOVERGENQ53H47
HOGENOMQ53H47
Homologs : HomoloGeneSETMAR
Homology/Alignments : Family Browser (UCSC)SETMAR
Gene fusions - Rearrangements
Fusion : MitelmanITPR1/SETMAR [3p26.1/3p26.1]  [t(3;3)(p26;p26)]  
Fusion : MitelmanKSR2/SETMAR [12q24.22/3p26.1]  [t(3;12)(p26;q24)]  
Fusion: TCGAITPR1 3p26.1 SETMAR 3p26.1 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSETMAR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SETMAR
dbVarSETMAR
ClinVarSETMAR
1000_GenomesSETMAR 
Exome Variant ServerSETMAR
ExAC (Exome Aggregation Consortium)SETMAR (select the gene name)
Genetic variants : HAPMAP6419
Genomic Variants (DGV)SETMAR [DGVbeta]
DECIPHERSETMAR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSETMAR 
Mutations
ICGC Data PortalSETMAR 
TCGA Data PortalSETMAR 
Broad Tumor PortalSETMAR
OASIS PortalSETMAR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSETMAR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSETMAR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SETMAR
DgiDB (Drug Gene Interaction Database)SETMAR
DoCM (Curated mutations)SETMAR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SETMAR (select a term)
intoGenSETMAR
Cancer3DSETMAR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609834   
Orphanet
MedgenSETMAR
Genetic Testing Registry SETMAR
NextProtQ53H47 [Medical]
TSGene6419
GENETestsSETMAR
Huge Navigator SETMAR [HugePedia]
snp3D : Map Gene to Disease6419
BioCentury BCIQSETMAR
ClinGenSETMAR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6419
Chemical/Pharm GKB GenePA35680
Clinical trialSETMAR
Miscellaneous
canSAR (ICR)SETMAR (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSETMAR
EVEXSETMAR
GoPubMedSETMAR
iHOPSETMAR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:36:49 CEST 2017

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