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SF3B6 (splicing factor 3b, subunit 6, 14kDa)

Identity

Alias_namessplicing factor 3b, subunit 6, 14kDa
Alias_symbol (synonym)P14
SF3B14a
Ht006
CGI-110
SAP14a
Other aliasHSPC175
SAP14
SF3B14
HGNC (Hugo) SF3B6
LocusID (NCBI) 51639
Atlas_Id 73165
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 24290454 and ends at 24299314 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SF3B6 (2p23.3) / SF3B6 (2p23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SF3B6   30096
Cards
Entrez_Gene (NCBI)SF3B6  51639  splicing factor 3b, subunit 6, 14kDa
AliasesCGI-110; HSPC175; Ht006; P14; 
SAP14; SAP14a; SF3B14; SF3B14a
GeneCards (Weizmann)SF3B6
Ensembl hg19 (Hinxton)ENSG00000115128 [Gene_View]  chr2:24290454-24299314 [Contig_View]  SF3B6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000115128 [Gene_View]  chr2:24290454-24299314 [Contig_View]  SF3B6 [Vega]
ICGC DataPortalENSG00000115128
TCGA cBioPortalSF3B6
AceView (NCBI)SF3B6
Genatlas (Paris)SF3B6
WikiGenes51639
SOURCE (Princeton)SF3B6
Genetics Home Reference (NIH)SF3B6
Genomic and cartography
GoldenPath hg19 (UCSC)SF3B6  -     chr2:24290454-24299314 -  2p23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SF3B6  -     2p23.3   [Description]    (hg38-Dec_2013)
EnsemblSF3B6 - 2p23.3 [CytoView hg19]  SF3B6 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBISF3B6 [Mapview hg19]  SF3B6 [Mapview hg38]
OMIM607835   
Gene and transcription
Genbank (Entrez)AF151868 AF161523 AF184213 AF401310 AK000621
RefSeq transcript (Entrez)NM_016047
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)SF3B6
Cluster EST : UnigeneHs.177861 [ NCBI ]
CGAP (NCI)Hs.177861
Alternative Splicing GalleryENSG00000115128
Gene ExpressionSF3B6 [ NCBI-GEO ]   SF3B6 [ EBI - ARRAY_EXPRESS ]   SF3B6 [ SEEK ]   SF3B6 [ MEM ]
Gene Expression Viewer (FireBrowse)SF3B6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51639
GTEX Portal (Tissue expression)SF3B6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3B4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3B4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3B4
Splice isoforms : SwissVarQ9Y3B4
PhosPhoSitePlusQ9Y3B4
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)SF3B6
DMDM Disease mutations51639
Blocks (Seattle)SF3B6
PDB (SRS)2F9D    2F9J    2FHO    3LQV   
PDB (PDBSum)2F9D    2F9J    2FHO    3LQV   
PDB (IMB)2F9D    2F9J    2FHO    3LQV   
PDB (RSDB)2F9D    2F9J    2FHO    3LQV   
Structural Biology KnowledgeBase2F9D    2F9J    2FHO    3LQV   
SCOP (Structural Classification of Proteins)2F9D    2F9J    2FHO    3LQV   
CATH (Classification of proteins structures)2F9D    2F9J    2FHO    3LQV   
SuperfamilyQ9Y3B4
Human Protein AtlasENSG00000115128
Peptide AtlasQ9Y3B4
HPRD09702
IPIIPI00032827   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3B4
IntAct (EBI)Q9Y3B4
FunCoupENSG00000115128
BioGRIDSF3B6
STRING (EMBL)SF3B6
ZODIACSF3B6
Ontologies - Pathways
QuickGOQ9Y3B4
Ontology : AmiGOnucleotide binding  mRNA splicing, via spliceosome  nucleoplasm  nucleoplasm  U12-type spliceosomal complex  RNA splicing  gene expression  poly(A) RNA binding  
Ontology : EGO-EBInucleotide binding  mRNA splicing, via spliceosome  nucleoplasm  nucleoplasm  U12-type spliceosomal complex  RNA splicing  gene expression  poly(A) RNA binding  
NDEx NetworkSF3B6
Atlas of Cancer Signalling NetworkSF3B6
Wikipedia pathwaysSF3B6
Orthology - Evolution
OrthoDB51639
GeneTree (enSembl)ENSG00000115128
Phylogenetic Trees/Animal Genes : TreeFamSF3B6
HOVERGENQ9Y3B4
HOGENOMQ9Y3B4
Homologs : HomoloGeneSF3B6
Homology/Alignments : Family Browser (UCSC)SF3B6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSF3B6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SF3B6
dbVarSF3B6
ClinVarSF3B6
1000_GenomesSF3B6 
Exome Variant ServerSF3B6
ExAC (Exome Aggregation Consortium)SF3B6 (select the gene name)
Genetic variants : HAPMAP51639
Genomic Variants (DGV)SF3B6 [DGVbeta]
DECIPHER (Syndromes)2:24290454-24299314  ENSG00000115128
CONAN: Copy Number AnalysisSF3B6 
Mutations
ICGC Data PortalSF3B6 
TCGA Data PortalSF3B6 
Broad Tumor PortalSF3B6
OASIS PortalSF3B6 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSF3B6
BioMutasearch SF3B6
DgiDB (Drug Gene Interaction Database)SF3B6
DoCM (Curated mutations)SF3B6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SF3B6 (select a term)
intoGenSF3B6
Cancer3DSF3B6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607835   
Orphanet
MedgenSF3B6
Genetic Testing Registry SF3B6
NextProtQ9Y3B4 [Medical]
TSGene51639
GENETestsSF3B6
Huge Navigator SF3B6 [HugePedia]
snp3D : Map Gene to Disease51639
BioCentury BCIQSF3B6
ClinGenSF3B6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51639
Clinical trialSF3B6
Miscellaneous
canSAR (ICR)SF3B6 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSF3B6
EVEXSF3B6
GoPubMedSF3B6
iHOPSF3B6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:42:56 CET 2017

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