Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SFI1 (SFI1 centrin binding protein)

Identity

Alias_namesregulatory subunit 139
Alias_symbol (synonym)KIAA0542
PISD
PPP1R139
Other aliashSfi1p
HGNC (Hugo) SFI1
LocusID (NCBI) 9814
Atlas_Id 54614
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 31892125 and ends at 32014537 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DEPDC5 (22q12.2) / SFI1 (22q12.2)SFI1 (22q12.2) / LIMK2 (22q12.2)SFI1 (22q12.2) / TPST2 (22q12.1)
SFI1 (22q12.2) / YPEL1 (22q11.21)SLC35A3 (1p21.2) / SFI1 (22q12.2)DEPDC5 22q12.2 / SFI1 22q12.2
SFI1 22q12.2 / LIMK2 22q12.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SFI1   29064
Cards
Entrez_Gene (NCBI)SFI1  9814  SFI1 centrin binding protein
AliasesPISD; PPP1R139; hSfi1p
GeneCards (Weizmann)SFI1
Ensembl hg19 (Hinxton)ENSG00000198089 [Gene_View]  chr22:31892125-32014537 [Contig_View]  SFI1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000198089 [Gene_View]  chr22:31892125-32014537 [Contig_View]  SFI1 [Vega]
ICGC DataPortalENSG00000198089
TCGA cBioPortalSFI1
AceView (NCBI)SFI1
Genatlas (Paris)SFI1
WikiGenes9814
SOURCE (Princeton)SFI1
Genetics Home Reference (NIH)SFI1
Genomic and cartography
GoldenPath hg19 (UCSC)SFI1  -     chr22:31892125-32014537 +  22q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SFI1  -     22q12.2   [Description]    (hg38-Dec_2013)
EnsemblSFI1 - 22q12.2 [CytoView hg19]  SFI1 - 22q12.2 [CytoView hg38]
Mapping of homologs : NCBISFI1 [Mapview hg19]  SFI1 [Mapview hg38]
OMIM612765   
Gene and transcription
Genbank (Entrez)AB011114 AI141022 AK055147 AK097004 AK292408
RefSeq transcript (Entrez)NM_001007467 NM_001258325 NM_001258326 NM_001258327 NM_014775
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)SFI1
Cluster EST : UnigeneHs.742373 [ NCBI ]
CGAP (NCI)Hs.742373
Alternative Splicing GalleryENSG00000198089
Gene ExpressionSFI1 [ NCBI-GEO ]   SFI1 [ EBI - ARRAY_EXPRESS ]   SFI1 [ SEEK ]   SFI1 [ MEM ]
Gene Expression Viewer (FireBrowse)SFI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9814
GTEX Portal (Tissue expression)SFI1
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8K8P3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8K8P3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8K8P3
Splice isoforms : SwissVarA8K8P3
PhosPhoSitePlusA8K8P3
Domains : Interpro (EBI)SFI1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)SFI1
DMDM Disease mutations9814
Blocks (Seattle)SFI1
PDB (SRS)2K2I   
PDB (PDBSum)2K2I   
PDB (IMB)2K2I   
PDB (RSDB)2K2I   
Structural Biology KnowledgeBase2K2I   
SCOP (Structural Classification of Proteins)2K2I   
CATH (Classification of proteins structures)2K2I   
SuperfamilyA8K8P3
Human Protein AtlasENSG00000198089
Peptide AtlasA8K8P3
HPRD11550
IPIIPI00001348   IPI00953352   IPI00816814   IPI00871555   IPI00853076   IPI00952862   IPI00877799   IPI00893862   IPI00894132   IPI00927621   IPI00925786   IPI00926432   IPI00975974   
Protein Interaction databases
DIP (DOE-UCLA)A8K8P3
IntAct (EBI)A8K8P3
FunCoupENSG00000198089
BioGRIDSFI1
STRING (EMBL)SFI1
ZODIACSFI1
Ontologies - Pathways
QuickGOA8K8P3
Ontology : AmiGOG2/M transition of mitotic cell cycle  protein binding  centriole  cytosol  negative regulation of phosphatase activity  phosphatase binding  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  protein binding  centriole  cytosol  negative regulation of phosphatase activity  phosphatase binding  
NDEx NetworkSFI1
Atlas of Cancer Signalling NetworkSFI1
Wikipedia pathwaysSFI1
Orthology - Evolution
OrthoDB9814
GeneTree (enSembl)ENSG00000198089
Phylogenetic Trees/Animal Genes : TreeFamSFI1
HOVERGENA8K8P3
HOGENOMA8K8P3
Homologs : HomoloGeneSFI1
Homology/Alignments : Family Browser (UCSC)SFI1
Gene fusions - Rearrangements
Fusion : MitelmanDEPDC5/SFI1 [22q12.2/22q12.2]  [t(22;22)(q12;q12)]  
Fusion : MitelmanSFI1/LIMK2 [22q12.2/22q12.2]  [t(22;22)(q12;q12)]  
Fusion : MitelmanSFI1/TPST2 [22q12.2/22q12.1]  [inv(22)(q12q12)]  
Fusion : MitelmanSFI1/YPEL1 [22q12.2/22q11.21]  [t(22;22)(q11;q12)]  
Fusion: TCGADEPDC5 22q12.2 SFI1 22q12.2 BRCA
Fusion: TCGASFI1 22q12.2 LIMK2 22q12.2 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSFI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SFI1
dbVarSFI1
ClinVarSFI1
1000_GenomesSFI1 
Exome Variant ServerSFI1
ExAC (Exome Aggregation Consortium)SFI1 (select the gene name)
Genetic variants : HAPMAP9814
Genomic Variants (DGV)SFI1 [DGVbeta]
DECIPHER (Syndromes)22:31892125-32014537  ENSG00000198089
CONAN: Copy Number AnalysisSFI1 
Mutations
ICGC Data PortalSFI1 
TCGA Data PortalSFI1 
Broad Tumor PortalSFI1
OASIS PortalSFI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSFI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSFI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SFI1
DgiDB (Drug Gene Interaction Database)SFI1
DoCM (Curated mutations)SFI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SFI1 (select a term)
intoGenSFI1
Cancer3DSFI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612765   
Orphanet
MedgenSFI1
Genetic Testing Registry SFI1
NextProtA8K8P3 [Medical]
TSGene9814
GENETestsSFI1
Huge Navigator SFI1 [HugePedia]
snp3D : Map Gene to Disease9814
BioCentury BCIQSFI1
ClinGenSFI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9814
Chemical/Pharm GKB GenePA142670930
Clinical trialSFI1
Miscellaneous
canSAR (ICR)SFI1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSFI1
EVEXSFI1
GoPubMedSFI1
iHOPSFI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:27:00 CET 2017

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