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SFMBT2 (Scm like with four mbt domains 2)

Identity

Alias (NCBI)-
HGNC (Hugo) SFMBT2
HGNC Alias symbKIAA1617
HGNC Previous nameScm-related gene containing four mbt domains 2
LocusID (NCBI) 57713
Atlas_Id 53482
Location 10p14  [Link to chromosome band 10p14]
Location_base_pair Starts at 7158624 and ends at 7411486 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DIP2C (10p15.3) / SFMBT2 (10p14)SFMBT2 (10p14) / PRKACB (1p31.1)SFMBT2 (10p14) / TGM2 (20q11.23)
SIK3 (11q23.3) / SFMBT2 (10p14)SFMBT2 10p14 / TGM2 20q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SFMBT2   20256
Cards
Entrez_Gene (NCBI)SFMBT2    Scm like with four mbt domains 2
Aliases
GeneCards (Weizmann)SFMBT2
Ensembl hg19 (Hinxton)ENSG00000198879 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198879 [Gene_View]  ENSG00000198879 [Sequence]  chr10:7158624-7411486 [Contig_View]  SFMBT2 [Vega]
ICGC DataPortalENSG00000198879
TCGA cBioPortalSFMBT2
AceView (NCBI)SFMBT2
Genatlas (Paris)SFMBT2
SOURCE (Princeton)SFMBT2
Genetics Home Reference (NIH)SFMBT2
Genomic and cartography
GoldenPath hg38 (UCSC)SFMBT2  -     chr10:7158624-7411486 -  10p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SFMBT2  -     10p14   [Description]    (hg19-Feb_2009)
GoldenPathSFMBT2 - 10p14 [CytoView hg19]  SFMBT2 - 10p14 [CytoView hg38]
ImmunoBaseENSG00000198879
Genome Data Viewer NCBISFMBT2 [Mapview hg19]  
OMIM615392   
Gene and transcription
Genbank (Entrez)AB046837 AK057130 AK090887 BC067242 BC144327
RefSeq transcript (Entrez)NM_001018039 NM_001029880 NM_001387889 NM_001387890 NM_001387891
Consensus coding sequences : CCDS (NCBI)SFMBT2
Gene ExpressionSFMBT2 [ NCBI-GEO ]   SFMBT2 [ EBI - ARRAY_EXPRESS ]   SFMBT2 [ SEEK ]   SFMBT2 [ MEM ]
Gene Expression Viewer (FireBrowse)SFMBT2 [ Firebrowse - Broad ]
GenevisibleExpression of SFMBT2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57713
GTEX Portal (Tissue expression)SFMBT2
Human Protein AtlasENSG00000198879-SFMBT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VUG0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VUG0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VUG0
PhosPhoSitePlusQ5VUG0
Domaine pattern : Prosite (Expaxy)MBT (PS51079)   
Domains : Interpro (EBI)Mbt    SAM    SAM/pointed_sf    Scm-like-4MBT1/2_SAM    SLED    SLED_sf   
Domain families : Pfam (Sanger)MBT (PF02820)    SAM_1 (PF00536)    SLED (PF12140)   
Domain families : Pfam (NCBI)pfam02820    pfam00536    pfam12140   
Domain families : Smart (EMBL)MBT (SM00561)  SAM (SM00454)  
Conserved Domain (NCBI)SFMBT2
PDB (RSDB)1WJR   
PDB Europe1WJR   
PDB (PDBSum)1WJR   
PDB (IMB)1WJR   
Structural Biology KnowledgeBase1WJR   
SCOP (Structural Classification of Proteins)1WJR   
CATH (Classification of proteins structures)1WJR   
SuperfamilyQ5VUG0
AlphaFold pdb e-kbQ5VUG0   
Human Protein Atlas [tissue]ENSG00000198879-SFMBT2 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q5VUG0
IntAct (EBI)Q5VUG0
BioGRIDSFMBT2
STRING (EMBL)SFMBT2
ZODIACSFMBT2
Ontologies - Pathways
QuickGOQ5VUG0
Ontology : AmiGOchromatin binding  transcription corepressor activity  protein binding  nucleus  nucleus  nucleoplasm  cytosol  negative regulation of gene expression  aggresome  nuclear body  nuclear speck  histone binding  histone binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  
Ontology : EGO-EBIchromatin binding  transcription corepressor activity  protein binding  nucleus  nucleus  nucleoplasm  cytosol  negative regulation of gene expression  aggresome  nuclear body  nuclear speck  histone binding  histone binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  
NDEx NetworkSFMBT2
Atlas of Cancer Signalling NetworkSFMBT2
Wikipedia pathwaysSFMBT2
Orthology - Evolution
OrthoDB57713
GeneTree (enSembl)ENSG00000198879
Phylogenetic Trees/Animal Genes : TreeFamSFMBT2
Homologs : HomoloGeneSFMBT2
Homology/Alignments : Family Browser (UCSC)SFMBT2
Gene fusions - Rearrangements
Fusion : MitelmanSFMBT2/PRKACB [10p14/1p31.1]  
Fusion : MitelmanSFMBT2/TGM2 [10p14/20q11.23]  
Fusion : QuiverSFMBT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSFMBT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SFMBT2
dbVarSFMBT2
ClinVarSFMBT2
MonarchSFMBT2
1000_GenomesSFMBT2 
Exome Variant ServerSFMBT2
GNOMAD BrowserENSG00000198879
Varsome BrowserSFMBT2
ACMGSFMBT2 variants
VarityQ5VUG0
Genomic Variants (DGV)SFMBT2 [DGVbeta]
DECIPHERSFMBT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSFMBT2 
Mutations
ICGC Data PortalSFMBT2 
TCGA Data PortalSFMBT2 
Broad Tumor PortalSFMBT2
OASIS PortalSFMBT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSFMBT2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSFMBT2
Mutations and Diseases : HGMDSFMBT2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSFMBT2
DgiDB (Drug Gene Interaction Database)SFMBT2
DoCM (Curated mutations)SFMBT2
CIViC (Clinical Interpretations of Variants in Cancer)SFMBT2
Cancer3DSFMBT2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615392   
Orphanet
DisGeNETSFMBT2
MedgenSFMBT2
Genetic Testing Registry SFMBT2
NextProtQ5VUG0 [Medical]
GENETestsSFMBT2
Target ValidationSFMBT2
Huge Navigator SFMBT2 [HugePedia]
ClinGenSFMBT2
Clinical trials, drugs, therapy
MyCancerGenomeSFMBT2
Protein Interactions : CTDSFMBT2
Pharm GKB GenePA134866013
PharosQ5VUG0
Clinical trialSFMBT2
Miscellaneous
canSAR (ICR)SFMBT2
HarmonizomeSFMBT2
DataMed IndexSFMBT2
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSFMBT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:30:53 CEST 2021

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