Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SFRP5 (secreted frizzled related protein 5)

Identity

Alias (NCBI)SARP3
HGNC (Hugo) SFRP5
HGNC Alias symbSARP3
HGNC Alias namesecreted apoptosis related protein 3
LocusID (NCBI) 6425
Atlas_Id 42278
Location 10q24.2  [Link to chromosome band 10q24]
Location_base_pair Starts at 97766751 and ends at 97771999 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLIT1 (10q24.1) / SFRP5 (10q24.2)SLIT1 10q24.1 / SFRP5 10q24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SFRP5   10779
Cards
Entrez_Gene (NCBI)SFRP5    secreted frizzled related protein 5
AliasesSARP3
GeneCards (Weizmann)SFRP5
Ensembl hg19 (Hinxton)ENSG00000120057 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120057 [Gene_View]  ENSG00000120057 [Sequence]  chr10:97766751-97771999 [Contig_View]  SFRP5 [Vega]
ICGC DataPortalENSG00000120057
TCGA cBioPortalSFRP5
AceView (NCBI)SFRP5
Genatlas (Paris)SFRP5
SOURCE (Princeton)SFRP5
Genetics Home Reference (NIH)SFRP5
Genomic and cartography
GoldenPath hg38 (UCSC)SFRP5  -     chr10:97766751-97771999 -  10q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SFRP5  -     10q24.2   [Description]    (hg19-Feb_2009)
GoldenPathSFRP5 - 10q24.2 [CytoView hg19]  SFRP5 - 10q24.2 [CytoView hg38]
ImmunoBaseENSG00000120057
Genome Data Viewer NCBISFRP5 [Mapview hg19]  
OMIM604158   
Gene and transcription
Genbank (Entrez)AF017988 AF117758 BC050435
RefSeq transcript (Entrez)NM_003015
Consensus coding sequences : CCDS (NCBI)SFRP5
Gene ExpressionSFRP5 [ NCBI-GEO ]   SFRP5 [ EBI - ARRAY_EXPRESS ]   SFRP5 [ SEEK ]   SFRP5 [ MEM ]
Gene Expression Viewer (FireBrowse)SFRP5 [ Firebrowse - Broad ]
GenevisibleExpression of SFRP5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6425
GTEX Portal (Tissue expression)SFRP5
Human Protein AtlasENSG00000120057-SFRP5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T4F7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T4F7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T4F7
PhosPhoSitePlusQ5T4F7
Domaine pattern : Prosite (Expaxy)FZ (PS50038)    NTR (PS50189)   
Domains : Interpro (EBI)Frizzled/SFRP    Frizzled_dom    Frizzled_dom_sf    Netrin_domain    Netrin_module_non-TIMP    SFRP-5    SFRP5_CRD    TIMP-like_OB-fold   
Domain families : Pfam (Sanger)Fz (PF01392)    NTR (PF01759)   
Domain families : Pfam (NCBI)pfam01392    pfam01759   
Domain families : Smart (EMBL)C345C (SM00643)  FRI (SM00063)  
Conserved Domain (NCBI)SFRP5
SuperfamilyQ5T4F7
AlphaFold pdb e-kbQ5T4F7   
Human Protein Atlas [tissue]ENSG00000120057-SFRP5 [tissue]
HPRD09166
Protein Interaction databases
DIP (DOE-UCLA)Q5T4F7
IntAct (EBI)Q5T4F7
BioGRIDSFRP5
STRING (EMBL)SFRP5
ZODIACSFRP5
Ontologies - Pathways
QuickGOQ5T4F7
Ontology : AmiGOextracellular space  apoptotic process  establishment or maintenance of cell polarity  signal transduction  multicellular organism development  visual perception  negative regulation of cell population proliferation  anatomical structure morphogenesis  Wnt-protein binding  Wnt-protein binding  cell differentiation  negative regulation of Wnt signaling pathway  regulation of BMP signaling pathway  non-canonical Wnt signaling pathway  negative regulation of DNA-binding transcription factor activity  negative regulation of protein kinase B signaling  canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis  
Ontology : EGO-EBIextracellular space  apoptotic process  establishment or maintenance of cell polarity  signal transduction  multicellular organism development  visual perception  negative regulation of cell population proliferation  anatomical structure morphogenesis  Wnt-protein binding  Wnt-protein binding  cell differentiation  negative regulation of Wnt signaling pathway  regulation of BMP signaling pathway  non-canonical Wnt signaling pathway  negative regulation of DNA-binding transcription factor activity  negative regulation of protein kinase B signaling  canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis  
Pathways : KEGGWnt signaling pathway   
NDEx NetworkSFRP5
Atlas of Cancer Signalling NetworkSFRP5
Wikipedia pathwaysSFRP5
Orthology - Evolution
OrthoDB6425
GeneTree (enSembl)ENSG00000120057
Phylogenetic Trees/Animal Genes : TreeFamSFRP5
Homologs : HomoloGeneSFRP5
Homology/Alignments : Family Browser (UCSC)SFRP5
Gene fusions - Rearrangements
Fusion : MitelmanSLIT1/SFRP5 [10q24.1/10q24.2]  
Fusion : QuiverSFRP5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSFRP5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SFRP5
dbVarSFRP5
ClinVarSFRP5
MonarchSFRP5
1000_GenomesSFRP5 
Exome Variant ServerSFRP5
GNOMAD BrowserENSG00000120057
Varsome BrowserSFRP5
ACMGSFRP5 variants
VarityQ5T4F7
Genomic Variants (DGV)SFRP5 [DGVbeta]
DECIPHERSFRP5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSFRP5 
Mutations
ICGC Data PortalSFRP5 
TCGA Data PortalSFRP5 
Broad Tumor PortalSFRP5
OASIS PortalSFRP5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSFRP5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSFRP5
Mutations and Diseases : HGMDSFRP5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSFRP5
DgiDB (Drug Gene Interaction Database)SFRP5
DoCM (Curated mutations)SFRP5
CIViC (Clinical Interpretations of Variants in Cancer)SFRP5
Cancer3DSFRP5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604158   
Orphanet
DisGeNETSFRP5
MedgenSFRP5
Genetic Testing Registry SFRP5
NextProtQ5T4F7 [Medical]
GENETestsSFRP5
Target ValidationSFRP5
Huge Navigator SFRP5 [HugePedia]
ClinGenSFRP5
Clinical trials, drugs, therapy
MyCancerGenomeSFRP5
Protein Interactions : CTDSFRP5
Pharm GKB GenePA35695
PharosQ5T4F7
Clinical trialSFRP5
Miscellaneous
canSAR (ICR)SFRP5
HarmonizomeSFRP5
DataMed IndexSFRP5
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSFRP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:30:54 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.