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SFRS1 (splicing factor, arginine/serine-rich 1)

Identity

Other namesASF
MGC5228
SF2
SF2p33
SRp30a
HGNC (Hugo) SFRS1
Location 17q22
Location_base_pair Starts at 53433279 and ends at 53439706 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SFRS1   10780
Entrez_Gene (NCBI)SFRS1  6426  splicing factor, arginine/serine-rich 1
Cards
GeneCards (Weizmann)SFRS1
Ensembl (Hinxton)ENSG00000136450 [Gene_View]  SFRS1 [Vega]
AceView (NCBI)SFRS1
Genatlas (Paris)SFRS1
euGene (Indiana)6426
SOURCE (Stanford)NM_001078166 NM_006924
Gene Expression (Array Express) ENSG00000136450
Genomic and cartography
GoldenPath (UCSC)SFRS1  -  17q22   chr17:53433279-53439706 -  17q22   [Description]    (hg18-March_2006)
EnsemblSFRS1 - 17q22 [CytoView]
Mapping of homologs : NCBISFRS1 [Mapview]
OMIM600812   
Gene and transcription
Gene : Genbank (Entrez)AB062124 AB209558 AK225711 AK289933 AK312781
Reference sequence (RefSeq transcript) :SRSNM_001078166 NM_006924
Reference transcript : EntrezNM_001078166 NM_006924
RefSeq genomic : SRSAC_000060 AC_000149 NC_000017 NT_010783 NW_001838448 NW_926894
RefSeq genomic : EntrezAC_000060 AC_000149 NC_000017 NT_010783 NW_001838448 NW_926894
Consensus coding sequences : CCDS NCBISFRS1
Cluster EST : UnigeneHs.68714 [ SRS ] Hs.68714 [ NCBI ]
Alternative Splicing : Fast-db (Paris)13219
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ07955 (SRS) Q07955 (Expasy) Q07955 (Uniprot)
With graphics : InterProQ07955
Splice isoforms : VarSplice FASTAQ07955(VarSplice FASTA)
Domaine pattern : Prosite (SRS)RRM (PS50102)   
Domain pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (SRS)a_b_plait_nuc_bd    RRM_RNP1   
Domains : Interpro (EBI)a_b_plait_nuc_bd    RRM_RNP1   
Related proteins : CluSTrQ07955
Domain families : Pfam SRSRRM_1 (PF00076)   
Domain families : Pfam SangerRRM_1 (PF00076)   
Domain families : Pfam NCBIpfam00076   
Domain families : Smart EMBLRRM (SM00360)  
Blocks (Seattle)Q07955
Crystal structure of protein : PDB SRS1X4A    2O3D    3BEG   
Crystal structure of protein : PDBSum1X4A    2O3D    3BEG   
Crystal structure of protein : IMB1X4A    2O3D    3BEG   
Crystal structure of protein : PDB RSDB1X4A    2O3D    3BEG   
HPRD02887
Protein Interaction databases
DIP (DOE-UCLA)Q07955
IntAct (EBI)Q07955
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBISFRS1
SNP : GeneSNP UtahSFRS1
SNP : HGBaseSFRS1
Genetic variants : HAPMAPSFRS1
Somatic Mutations in Cancer : COSMICSFRS1 
Mutations and Diseases : HGMDSFRS1
Hereditary diseases : OMIM600812   
Hereditary diseases : GENETests600812   
Diseases : Genetic AssociationSFRS1
General knowledge
Homologs : HomoloGeneSFRS1
Homology/Alignments : Family Browser UCSCSFRS1
Phylogenetic Trees/Animal Genes : TreeFamSFRS1
Chemical/Protein Interactions : CTD6426
Keywords Ontology : AmiGOnucleotide binding  RNA binding  protein binding  nucleus  spliceosomal complex  cytoplasm  mRNA splice site selection  mRNA processing  RNA splicing  nuclear speck  
Keywords Ontology : EGO-EBInucleotide binding  RNA binding  protein binding  nucleus  spliceosomal complex  cytoplasm  mRNA splice site selection  mRNA processing  RNA splicing  nuclear speck  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesSFRS1 Related clones (RZPD - Berlin)
Literature
PubMed115 Pubmed reference(s) in Entrez
PubGeneSFRS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:40:49 CET 2010
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