Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SFTPA1 (surfactant protein A1)

Identity

Alias_namespulmonary-associated protein A1A
SFTP1
Alias_symbol (synonym)SP-A
SP-A1
COLEC4
Other aliasPSAP
PSP-A
PSPA
SFTPA1B
SPA
SPA1
HGNC (Hugo) SFTPA1
LocusID (NCBI) 653509
Atlas_Id 51251
Location 10q22.3  [Link to chromosome band 10q22]
Location_base_pair Starts at 81370695 and ends at 81375199 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SFTPA1   10798
Cards
Entrez_Gene (NCBI)SFTPA1  653509  surfactant protein A1
AliasesCOLEC4; PSAP; PSP-A; PSPA; 
SFTP1; SFTPA1B; SP-A; SP-A1; SPA; SPA1
GeneCards (Weizmann)SFTPA1
Ensembl hg19 (Hinxton)ENSG00000122852 [Gene_View]  chr10:81370695-81375199 [Contig_View]  SFTPA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000122852 [Gene_View]  chr10:81370695-81375199 [Contig_View]  SFTPA1 [Vega]
ICGC DataPortalENSG00000122852
TCGA cBioPortalSFTPA1
AceView (NCBI)SFTPA1
Genatlas (Paris)SFTPA1
WikiGenes653509
SOURCE (Princeton)SFTPA1
Genetics Home Reference (NIH)SFTPA1
Genomic and cartography
GoldenPath hg19 (UCSC)SFTPA1  -     chr10:81370695-81375199 +  10q22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SFTPA1  -     10q22.3   [Description]    (hg38-Dec_2013)
EnsemblSFTPA1 - 10q22.3 [CytoView hg19]  SFTPA1 - 10q22.3 [CytoView hg38]
Mapping of homologs : NCBISFTPA1 [Mapview hg19]  SFTPA1 [Mapview hg38]
OMIM178500   178630   
Gene and transcription
Genbank (Entrez)AK290703 AK298002 AK298029 AK298034 AK298092
RefSeq transcript (Entrez)NM_001093770 NM_001164644 NM_001164645 NM_001164646 NM_001164647 NM_005411
RefSeq genomic (Entrez)NC_000010 NC_018921 NG_021189 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)SFTPA1
Cluster EST : UnigeneHs.745476 [ NCBI ]
CGAP (NCI)Hs.745476
Alternative Splicing GalleryENSG00000122852
Gene ExpressionSFTPA1 [ NCBI-GEO ]   SFTPA1 [ EBI - ARRAY_EXPRESS ]   SFTPA1 [ SEEK ]   SFTPA1 [ MEM ]
Gene Expression Viewer (FireBrowse)SFTPA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)653509
GTEX Portal (Tissue expression)SFTPA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWL2
Splice isoforms : SwissVarQ8IWL2
PhosPhoSitePlusQ8IWL2
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin    C-type_lectin-like    C-type_lectin_CS    C-type_lectin_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)SFTPA1
DMDM Disease mutations653509
Blocks (Seattle)SFTPA1
SuperfamilyQ8IWL2
Human Protein AtlasENSG00000122852
Peptide AtlasQ8IWL2
IPIIPI00012889   IPI00739950   IPI00922027   IPI00845236   IPI00646877   IPI00944554   IPI00941049   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWL2
IntAct (EBI)Q8IWL2
FunCoupENSG00000122852
BioGRIDSFTPA1
STRING (EMBL)SFTPA1
ZODIACSFTPA1
Ontologies - Pathways
QuickGOQ8IWL2
Ontology : AmiGOlipid transporter activity  protein binding  extracellular region  proteinaceous extracellular matrix  collagen trimer  extracellular space  endoplasmic reticulum membrane  lipid transport  respiratory gaseous exchange  carbohydrate binding  lamellar body  cellular protein metabolic process  clathrin-coated endocytic vesicle  
Ontology : EGO-EBIlipid transporter activity  protein binding  extracellular region  proteinaceous extracellular matrix  collagen trimer  extracellular space  endoplasmic reticulum membrane  lipid transport  respiratory gaseous exchange  carbohydrate binding  lamellar body  cellular protein metabolic process  clathrin-coated endocytic vesicle  
Pathways : KEGGPhagosome    Pertussis   
NDEx NetworkSFTPA1
Atlas of Cancer Signalling NetworkSFTPA1
Wikipedia pathwaysSFTPA1
Orthology - Evolution
OrthoDB653509
GeneTree (enSembl)ENSG00000122852
Phylogenetic Trees/Animal Genes : TreeFamSFTPA1
HOVERGENQ8IWL2
HOGENOMQ8IWL2
Homologs : HomoloGeneSFTPA1
Homology/Alignments : Family Browser (UCSC)SFTPA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSFTPA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SFTPA1
dbVarSFTPA1
ClinVarSFTPA1
1000_GenomesSFTPA1 
Exome Variant ServerSFTPA1
ExAC (Exome Aggregation Consortium)SFTPA1 (select the gene name)
Genetic variants : HAPMAP653509
Genomic Variants (DGV)SFTPA1 [DGVbeta]
DECIPHER (Syndromes)10:81370695-81375199  ENSG00000122852
CONAN: Copy Number AnalysisSFTPA1 
Mutations
ICGC Data PortalSFTPA1 
TCGA Data PortalSFTPA1 
Broad Tumor PortalSFTPA1
OASIS PortalSFTPA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSFTPA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSFTPA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)TBsLVD Tuberculosis susceptibility Locus Variation Database
BioMutasearch SFTPA1
DgiDB (Drug Gene Interaction Database)SFTPA1
DoCM (Curated mutations)SFTPA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SFTPA1 (select a term)
intoGenSFTPA1
Cancer3DSFTPA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM178500    178630   
Orphanet7029   
MedgenSFTPA1
Genetic Testing Registry SFTPA1
NextProtQ8IWL2 [Medical]
TSGene653509
GENETestsSFTPA1
Huge Navigator SFTPA1 [HugePedia]
snp3D : Map Gene to Disease653509
BioCentury BCIQSFTPA1
ClinGenSFTPA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD653509
Chemical/Pharm GKB GenePA35710
Clinical trialSFTPA1
Miscellaneous
canSAR (ICR)SFTPA1 (select the gene name)
Probes
Litterature
PubMed163 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSFTPA1
EVEXSFTPA1
GoPubMedSFTPA1
iHOPSFTPA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:27:01 CET 2017

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