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SFTPC (surfactant protein C)

Identity

Other namesBRICD6
PSP-C
SFTP2
SMDP2
SP-C
HGNC (Hugo) SFTPC
LocusID (NCBI) 6440
Atlas_Id 53745
Location 8p21.3
Location_base_pair Starts at 22019184 and ends at 22021991 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
C15orf57 (15q15.1) / SFTPC (8p21.3)PDPK1 (16p13.3) / SFTPC (8p21.3)RGMA (15q26.1) / SFTPC (8p21.3)
SFTPC (8p21.3) / CGN (1q21.3)SFTPC (8p21.3) / IGLL5 (22q11.22)SFTPC (8p21.3) / SFTPC (8p21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SFTPC   10802
Cards
Entrez_Gene (NCBI)SFTPC  6440  surfactant protein C
AliasesBRICD6; PSP-C; SFTP2; SMDP2; 
SP-C
GeneCards (Weizmann)SFTPC
Ensembl hg19 (Hinxton)ENSG00000168484 [Gene_View]  chr8:22019184-22021991 [Contig_View]  SFTPC [Vega]
Ensembl hg38 (Hinxton)ENSG00000168484 [Gene_View]  chr8:22019184-22021991 [Contig_View]  SFTPC [Vega]
ICGC DataPortalENSG00000168484
TCGA cBioPortalSFTPC
AceView (NCBI)SFTPC
Genatlas (Paris)SFTPC
WikiGenes6440
SOURCE (Princeton)SFTPC
Genomic and cartography
GoldenPath hg19 (UCSC)SFTPC  -     chr8:22019184-22021991 +  8p21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SFTPC  -     8p21.3   [Description]    (hg38-Dec_2013)
EnsemblSFTPC - 8p21.3 [CytoView hg19]  SFTPC - 8p21.3 [CytoView hg38]
Mapping of homologs : NCBISFTPC [Mapview hg19]  SFTPC [Mapview hg38]
OMIM178500   178620   610913   
Gene and transcription
Genbank (Entrez)AK058094 AK298119 AK315742 BC005913 BC105594
RefSeq transcript (Entrez)NM_001172357 NM_001172410 NM_001317778 NM_001317779 NM_001317780 NM_003018
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_016968 NG_029659 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)SFTPC
Cluster EST : UnigeneHs.1074 [ NCBI ]
CGAP (NCI)Hs.1074
Alternative Splicing GalleryENSG00000168484
Gene ExpressionSFTPC [ NCBI-GEO ]   SFTPC [ EBI - ARRAY_EXPRESS ]   SFTPC [ SEEK ]   SFTPC [ MEM ]
Gene Expression Viewer (FireBrowse)SFTPC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6440
GTEX Portal (Tissue expression)SFTPC
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11686 (Uniprot)
NextProtP11686  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11686
Splice isoforms : SwissVarP11686 (Swissvar)
PhosPhoSitePlusP11686
Domaine pattern : Prosite (Expaxy)BRICHOS (PS50869)    SURFACT_PALMITOYL (PS00341)   
Domains : Interpro (EBI)BRICHOS_dom    Pulm_surfact_AP    SP-C_palmitoylation_site    Surfactant_protein_propep   
Domain families : Pfam (Sanger)BRICHOS (PF04089)    SP_C-Propep (PF08999)   
Domain families : Pfam (NCBI)pfam04089    pfam08999   
Domain families : Smart (EMBL)BRICHOS (SM01039)  SF_P (SM00019)  
DMDM Disease mutations6440
Blocks (Seattle)SFTPC
PDB (SRS)2YAD   
PDB (PDBSum)2YAD   
PDB (IMB)2YAD   
PDB (RSDB)2YAD   
Structural Biology KnowledgeBase2YAD   
SCOP (Structural Classification of Proteins)2YAD   
CATH (Classification of proteins structures)2YAD   
SuperfamilyP11686
Human Protein AtlasENSG00000168484
Peptide AtlasP11686
HPRD01520
IPIIPI00006707   IPI00218499   IPI01008760   IPI00792510   IPI00793845   IPI00939469   IPI00794401   IPI00979021   IPI00974461   
Protein Interaction databases
DIP (DOE-UCLA)P11686
IntAct (EBI)P11686
FunCoupENSG00000168484
BioGRIDSFTPC
STRING (EMBL)SFTPC
ZODIACSFTPC
Ontologies - Pathways
QuickGOP11686
Ontology : AmiGOprotein binding  extracellular region  extracellular space  endoplasmic reticulum membrane  respiratory gaseous exchange  lamellar body  cellular protein metabolic process  clathrin-coated endocytic vesicle  multivesicular body lumen  
Ontology : EGO-EBIprotein binding  extracellular region  extracellular space  endoplasmic reticulum membrane  respiratory gaseous exchange  lamellar body  cellular protein metabolic process  clathrin-coated endocytic vesicle  multivesicular body lumen  
NDEx Network
Atlas of Cancer Signalling NetworkSFTPC
Wikipedia pathwaysSFTPC
Orthology - Evolution
OrthoDB6440
GeneTree (enSembl)ENSG00000168484
Phylogenetic Trees/Animal Genes : TreeFamSFTPC
Homologs : HomoloGeneSFTPC
Homology/Alignments : Family Browser (UCSC)SFTPC
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSFTPC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SFTPC
dbVarSFTPC
ClinVarSFTPC
1000_GenomesSFTPC 
Exome Variant ServerSFTPC
ExAC (Exome Aggregation Consortium)SFTPC (select the gene name)
Genetic variants : HAPMAP6440
Genomic Variants (DGV)SFTPC [DGVbeta]
Mutations
ICGC Data PortalSFTPC 
TCGA Data PortalSFTPC 
Broad Tumor PortalSFTPC
OASIS PortalSFTPC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSFTPC 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SFTPC
DgiDB (Drug Gene Interaction Database)SFTPC
DoCM (Curated mutations)SFTPC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SFTPC (select a term)
intoGenSFTPC
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)8:22019184-22021991  ENSG00000168484
CONAN: Copy Number AnalysisSFTPC 
Mutations and Diseases : HGMDSFTPC
OMIM178500    178620    610913   
MedgenSFTPC
Genetic Testing Registry SFTPC
NextProtP11686 [Medical]
TSGene6440
GENETestsSFTPC
Huge Navigator SFTPC [HugePedia]
snp3D : Map Gene to Disease6440
BioCentury BCIQSFTPC
ClinGenSFTPC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6440
Chemical/Pharm GKB GenePA35714
Clinical trialSFTPC
Miscellaneous
canSAR (ICR)SFTPC (select the gene name)
Probes
Litterature
PubMed99 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSFTPC
EVEXSFTPC
GoPubMedSFTPC
iHOPSFTPC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 11:20:51 CEST 2016

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