Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SGK2 (serum/glucocorticoid regulated kinase 2)

Identity

Other namesH-SGK2
dJ138B7.2
HGNC (Hugo) SGK2
LocusID (NCBI) 10110
Location 20q13.12
Location_base_pair Starts at 42193755 and ends at 42214273 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SGK2   13900
Entrez_Gene (NCBI)SGK2  10110  serum/glucocorticoid regulated kinase 2
Cards
GeneCards (Weizmann)SGK2
Ensembl (Hinxton)ENSG00000101049 [Gene_View]  chr20:42193755-42214273 [Contig_View]  SGK2 [Vega]
AceView (NCBI)SGK2
Genatlas (Paris)SGK2
SOURCE (Stanford)NM_001199264 NM_016276 NM_170693
Genomic and cartography
GoldenPath (UCSC)SGK2  -  20q13.12   chr20:42193755-42214273 +  20q13.12   [Description]    (hg19-Feb_2009)
EnsemblSGK2 - 20q13.12 [CytoView]
Mapping of homologs : NCBISGK2 [Mapview]
OMIM607589   
Gene and transcription
Genbank (Entrez)AF169034 AF186470 AK289596 AK308502 AY987010
RefSeq transcript (SRS)NM_001199264 NM_016276 NM_170693
RefSeq transcript (Entrez)NM_001199264 NM_016276 NM_170693
RefSeq genomic (SRS)AC_000152 NC_000020 NC_018931 NG_029448 NT_011362 NW_001838666 NW_004078102
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NG_029448 NT_011362 NW_001838666 NW_004078102
Consensus coding sequences : CCDS (NCBI)SGK2
Cluster EST : UnigeneHs.740147 [ SRS ] Hs.740147 [ NCBI ]
CGAP (NCI)Hs.740147
Alternative Splicing : Fast-db (Paris)GSHG0018759
Alternative Splicing GalleryENSG00000101049
Gene ExpressionSGK2 [ NCBI-GEO ]   SGK2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBY8 (SRS) Q9HBY8 (Uniprot)
NextProtQ9HBY8
With graphics : InterProQ9HBY8
Splice isoforms : SwissVarQ9HBY8(Swissvar)
Domaine pattern : Prosite (SRS)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (SRS)AGC-kinase_C    Kinase-like_dom    Pkinase_C    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom    Pkinase_C    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Related proteins : CluSTrQ9HBY8
Domain families : Pfam (SRS)Pkinase (PF00069)    Pkinase_C (PF00433)   
Domain families : Pfam (Sanger)Pkinase (PF00069)    Pkinase_C (PF00433)   
Domain families : Pfam (NCBI)pfam00069    pfam00433   
Domain families : Smart (EMBL)S_TK_X (SM00133)  S_TKc (SM00220)  
DMDM10110
Blocks (Seattle)Q9HBY8
Human Protein AtlasENSG00000101049
HPRD06348
IPIIPI00009887   IPI00217154   IPI00853438   IPI00867534   IPI01014385   IPI00644787   IPI00827798   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBY8
IntAct (EBI)Q9HBY8
FunCoupENSG00000101049
REACTOMESGK2
Protein Interaction Database10110
BioGRIDSGK2
InParanoidQ9HBY8
Interologous Interaction database Q9HBY8
IntegromeDBSGK2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SGK2
SNP (GeneSNP Utah)SGK2
SNP : HGBaseSGK2
Genetic variants : HAPMAPSGK2
Somatic Mutations in Cancer : COSMICSGK2 
CONAN: Copy Number AnalysisSGK2 
Mutations and Diseases : HGMDSGK2
OMIM607589   
GENETests607589   
Disease Genetic AssociationSGK2
Huge Navigator SGK2 [HugePedia]  SGK2 [HugeCancerGEM]
Genomic VariantsSGK2  SGK2 [DGVbeta]
snp3D : Map Gene to Disease10110
General knowledge
Homologs : HomoloGeneSGK2
Homology/Alignments : Family Browser (UCSC)SGK2
Phylogenetic Trees/Animal Genes : TreeFamSGK2
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
Chemical/Protein Interactions : CTD10110
Chemical/Pharm GKB GenePA37824
Clinical trialSGK2
Cancer Resource (Charite)ENSG00000101049
Ontology : AmiGOregulation of cell growth  protein serine/threonine kinase activity  ATP binding  cellular_component  nucleus  cytoplasm  protein phosphorylation  response to oxidative stress  intracellular protein kinase cascade  potassium channel regulator activity  sodium channel regulator activity  sodium channel regulator activity  positive regulation of transporter activity  regulation of cell proliferation  
Ontology : EGO-EBIregulation of cell growth  protein serine/threonine kinase activity  ATP binding  cellular_component  nucleus  cytoplasm  protein phosphorylation  response to oxidative stress  intracellular protein kinase cascade  potassium channel regulator activity  sodium channel regulator activity  sodium channel regulator activity  positive regulation of transporter activity  regulation of cell proliferation  
Other databases
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
PubGeneSGK2
iHOPSGK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:42:16 CEST 2013
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