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SGPP1 (sphingosine-1-phosphate phosphatase 1)

Identity

Other aliasSPPase1
HGNC (Hugo) SGPP1
LocusID (NCBI) 81537
Atlas_Id 55542
Location 14q23.2  [Link to chromosome band 14q23]
Location_base_pair Starts at 63684216 and ends at 63728095 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LIMCH1 (4p13) / SGPP1 (14q23.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SGPP1   17720
Cards
Entrez_Gene (NCBI)SGPP1  81537  sphingosine-1-phosphate phosphatase 1
AliasesSPPase1
GeneCards (Weizmann)SGPP1
Ensembl hg19 (Hinxton)ENSG00000126821 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126821 [Gene_View]  chr14:63684216-63728095 [Contig_View]  SGPP1 [Vega]
ICGC DataPortalENSG00000126821
TCGA cBioPortalSGPP1
AceView (NCBI)SGPP1
Genatlas (Paris)SGPP1
WikiGenes81537
SOURCE (Princeton)SGPP1
Genetics Home Reference (NIH)SGPP1
Genomic and cartography
GoldenPath hg38 (UCSC)SGPP1  -     chr14:63684216-63728095 -  14q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SGPP1  -     14q23.2   [Description]    (hg19-Feb_2009)
EnsemblSGPP1 - 14q23.2 [CytoView hg19]  SGPP1 - 14q23.2 [CytoView hg38]
Mapping of homologs : NCBISGPP1 [Mapview hg19]  SGPP1 [Mapview hg38]
OMIM612826   
Gene and transcription
Genbank (Entrez)AF349315 AJ293294 AK314188 BC063839 BC070060
RefSeq transcript (Entrez)NM_030791
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SGPP1
Cluster EST : UnigeneHs.24678 [ NCBI ]
CGAP (NCI)Hs.24678
Alternative Splicing GalleryENSG00000126821
Gene ExpressionSGPP1 [ NCBI-GEO ]   SGPP1 [ EBI - ARRAY_EXPRESS ]   SGPP1 [ SEEK ]   SGPP1 [ MEM ]
Gene Expression Viewer (FireBrowse)SGPP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81537
GTEX Portal (Tissue expression)SGPP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BX95   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BX95  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BX95
Splice isoforms : SwissVarQ9BX95
Catalytic activity : Enzyme3.1.3.- [ Enzyme-Expasy ]   3.1.3.-3.1.3.- [ IntEnz-EBI ]   3.1.3.- [ BRENDA ]   3.1.3.- [ KEGG ]   
PhosPhoSitePlusQ9BX95
Domains : Interpro (EBI)P_Acid_Pase_2/haloperoxidase   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)SGPP1
DMDM Disease mutations81537
Blocks (Seattle)SGPP1
SuperfamilyQ9BX95
Human Protein AtlasENSG00000126821
Peptide AtlasQ9BX95
HPRD10226
IPIIPI00306840   
Protein Interaction databases
DIP (DOE-UCLA)Q9BX95
IntAct (EBI)Q9BX95
FunCoupENSG00000126821
BioGRIDSGPP1
STRING (EMBL)SGPP1
ZODIACSGPP1
Ontologies - Pathways
QuickGOQ9BX95
Ontology : AmiGOendoplasmic reticulum membrane  sphinganine-1-phosphate metabolic process  sphingosine metabolic process  integral component of membrane  dephosphorylation  sphingolipid biosynthetic process  sphingosine-1-phosphate phosphatase activity  dihydrosphingosine-1-phosphate phosphatase activity  extrinsic apoptotic signaling pathway  intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIendoplasmic reticulum membrane  sphinganine-1-phosphate metabolic process  sphingosine metabolic process  integral component of membrane  dephosphorylation  sphingolipid biosynthetic process  sphingosine-1-phosphate phosphatase activity  dihydrosphingosine-1-phosphate phosphatase activity  extrinsic apoptotic signaling pathway  intrinsic apoptotic signaling pathway  
Pathways : KEGGSphingolipid metabolism   
NDEx NetworkSGPP1
Atlas of Cancer Signalling NetworkSGPP1
Wikipedia pathwaysSGPP1
Orthology - Evolution
OrthoDB81537
GeneTree (enSembl)ENSG00000126821
Phylogenetic Trees/Animal Genes : TreeFamSGPP1
HOVERGENQ9BX95
HOGENOMQ9BX95
Homologs : HomoloGeneSGPP1
Homology/Alignments : Family Browser (UCSC)SGPP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSGPP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SGPP1
dbVarSGPP1
ClinVarSGPP1
1000_GenomesSGPP1 
Exome Variant ServerSGPP1
ExAC (Exome Aggregation Consortium)SGPP1 (select the gene name)
Genetic variants : HAPMAP81537
Genomic Variants (DGV)SGPP1 [DGVbeta]
DECIPHERSGPP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSGPP1 
Mutations
ICGC Data PortalSGPP1 
TCGA Data PortalSGPP1 
Broad Tumor PortalSGPP1
OASIS PortalSGPP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSGPP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSGPP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SGPP1
DgiDB (Drug Gene Interaction Database)SGPP1
DoCM (Curated mutations)SGPP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SGPP1 (select a term)
intoGenSGPP1
Cancer3DSGPP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612826   
Orphanet
MedgenSGPP1
Genetic Testing Registry SGPP1
NextProtQ9BX95 [Medical]
TSGene81537
GENETestsSGPP1
Huge Navigator SGPP1 [HugePedia]
snp3D : Map Gene to Disease81537
BioCentury BCIQSGPP1
ClinGenSGPP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81537
Chemical/Pharm GKB GenePA134884424
Clinical trialSGPP1
Miscellaneous
canSAR (ICR)SGPP1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSGPP1
EVEXSGPP1
GoPubMedSGPP1
iHOPSGPP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:37:00 CEST 2017

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