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SGPP2 (sphingosine-1-phosphate phosphatase 2)

Identity

Alias_symbol (synonym)SPP2
FLJ39004
Other aliasSPPase2
HGNC (Hugo) SGPP2
LocusID (NCBI) 130367
Atlas_Id 73188
Location 2q36.1  [Link to chromosome band 2q36]
Location_base_pair Starts at 222424707 aod(ends at 222562622 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NDUFA10 (2q37.3) / SGPP2 (2q36.1)SGPP2 (2q36.1) / ALG14 (1p21.3)SGPP2 (2q36.1) / FAM13A (4q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SGPP2   19953
Cards
Entrez_Gene (NCBI)SGPP2  130367  sphingosine-1-phosphate phosphatase 2
AliasesSPP2; SPPase2
GeneCards (Weizmann)SGPP2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:222424507-222562622 [Contig_View]  SGPP2 [Vega]
TCGA cBioPortalSGPP2
AceView (NCBI)SGPP2
Genatlas (Paris)SGPP2
WikiGenes130367
SOURCE (Princeton)SGPP2
Genetics Home Reference (NIH)SGPP2
Genomic and cartography
GoldenPath hg38 (UCSC)SGPP2  -     chr2:222424507-222562622 +  2q36.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SGPP2  -     2q36.1   [Description]    (hg19-Feb_2009)
EnsemblSGPP2 - 2q36.1 [CytoView hg19]  SGPP2 - 2q36.1 [CytoView hg38]
Mapping of homologs : NCBISGPP2 [Mapview hg19]  SGPP2 [Mapview hg38]
OMIM612827   
Gene and transcription
Genbank (Entrez)AF542512 AK096323 AK314322 BC106904 BC106905
RefSeq transcript (Entrez)NM_001320833 NM_001320834 NM_152386
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SGPP2
Cluster EST : UnigeneHs.591604 [ NCBI ]
CGAP (NCI)Hs.591604
Gene ExpressionSGPP2 [ NCBI-GEO ]   SGPP2 [ EBI - ARRAY_EXPRESS ]   SGPP2 [ SEEK ]   SGPP2 [ MEM ]
Gene Expression Viewer (FireBrowse)SGPP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)130367
GTEX Portal (Tissue expression)SGPP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWX5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWX5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWX5
Splice isoforms : SwissVarQ8IWX5
Catalytic activity : Enzyme3.1.3.- [ Enzyme-Expasy ]   3.1.3.-3.1.3.- [ IntEnz-EBI ]   3.1.3.- [ BRENDA ]   3.1.3.- [ KEGG ]   
PhosPhoSitePlusQ8IWX5
Domains : Interpro (EBI)P_Acid_Pase_2/haloperoxidase   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)SGPP2
DMDM Disease mutations130367
Blocks (Seattle)SGPP2
SuperfamilyQ8IWX5
Peptide AtlasQ8IWX5
HPRD18048
IPIIPI00217427   IPI00787315   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWX5
IntAct (EBI)Q8IWX5
BioGRIDSGPP2
STRING (EMBL)SGPP2
ZODIACSGPP2
Ontologies - Pathways
QuickGOQ8IWX5
Ontology : AmiGOendoplasmic reticulum  endoplasmic reticulum membrane  sphingosine metabolic process  integral component of membrane  dephosphorylation  sphingolipid biosynthetic process  sphingosine-1-phosphate phosphatase activity  sphingosine-1-phosphate phosphatase activity  dihydrosphingosine-1-phosphate phosphatase activity  
Ontology : EGO-EBIendoplasmic reticulum  endoplasmic reticulum membrane  sphingosine metabolic process  integral component of membrane  dephosphorylation  sphingolipid biosynthetic process  sphingosine-1-phosphate phosphatase activity  sphingosine-1-phosphate phosphatase activity  dihydrosphingosine-1-phosphate phosphatase activity  
Pathways : KEGGSphingolipid metabolism   
NDEx NetworkSGPP2
Atlas of Cancer Signalling NetworkSGPP2
Wikipedia pathwaysSGPP2
Orthology - Evolution
OrthoDB130367
Phylogenetic Trees/Animal Genes : TreeFamSGPP2
HOVERGENQ8IWX5
HOGENOMQ8IWX5
Homologs : HomoloGeneSGPP2
Homology/Alignments : Family Browser (UCSC)SGPP2
Gene fusions - Rearrangements
Tumor Fusion PortalSGPP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSGPP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SGPP2
dbVarSGPP2
ClinVarSGPP2
1000_GenomesSGPP2 
Exome Variant ServerSGPP2
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP130367
Genomic Variants (DGV)SGPP2 [DGVbeta]
DECIPHERSGPP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSGPP2 
Mutations
ICGC Data PortalSGPP2 
TCGA Data PortalSGPP2 
Broad Tumor PortalSGPP2
OASIS PortalSGPP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSGPP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSGPP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SGPP2
DgiDB (Drug Gene Interaction Database)SGPP2
DoCM (Curated mutations)SGPP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SGPP2 (select a term)
intoGenSGPP2
Cancer3DSGPP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612827   
Orphanet
DisGeNETSGPP2
MedgenSGPP2
Genetic Testing Registry SGPP2
NextProtQ8IWX5 [Medical]
TSGene130367
GENETestsSGPP2
Target ValidationSGPP2
Huge Navigator SGPP2 [HugePedia]
snp3D : Map Gene to Disease130367
BioCentury BCIQSGPP2
ClinGenSGPP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD130367
Chemical/Pharm GKB GenePA134956234
Clinical trialSGPP2
Miscellaneous
canSAR (ICR)SGPP2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSGPP2
EVEXSGPP2
GoPubMedSGPP2
iHOPSGPP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:06:18 CET 2017

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