SGSM1 (small G protein signaling modulator 1)

2016-10-01  

Identity

HGNC
LOCATION
22q11.23
LOCUSID
ALIAS
RUTBC2
FUSION GENES

Other Information

Locus ID:

NCBI: 129049
MIM: 611417
HGNC: 29410
Ensembl: ENSG00000167037

Variants:

dbSNP: 129049
ClinVar: 129049
TCGA: ENSG00000167037
COSMIC: SGSM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167037ENST00000400358Q2NKQ1
ENSG00000167037ENST00000400359Q2NKQ1
ENSG00000167037ENST00000610372A0A087X241

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
175098192007Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.22
226374802012RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.13
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
305735202019Hypermethylation of SHISA3 Promotes Nasopharyngeal Carcinoma Metastasis by Reducing SGSM1 Stability.5

Citation

Dessen P

SGSM1 (small G protein signaling modulator 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56193/sgsm1