Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SGTA (small glutamine rich tetratricopeptide repeat containing alpha)

Identity

Alias_namesSGT
small glutamine-rich tetratricopeptide repeat (TPR)-containing
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
Other aliasalphaSGT
hSGT
HGNC (Hugo) SGTA
LocusID (NCBI) 6449
Atlas_Id 50154
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 2754714 and ends at 2783356 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HAUS8 (19p13.11) / SGTA (19p13.3)SGTA (19p13.3) / PSMF1 (20p13)SGTA (19p13.3) / TXNDC5 (6p24.3)
SGTA (19p13.3) / YIPF3 (6p21.1)SLC39A3 (19p13.3) / SGTA (19p13.3)HAUS8 19p13.11 / SGTA 19p13.3
SLC39A3 19p13.3 / SGTA 19p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SGTA   10819
Cards
Entrez_Gene (NCBI)SGTA  6449  small glutamine rich tetratricopeptide repeat containing alpha
AliasesSGT; alphaSGT; hSGT
GeneCards (Weizmann)SGTA
Ensembl hg19 (Hinxton)ENSG00000104969 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104969 [Gene_View]  chr19:2754714-2783356 [Contig_View]  SGTA [Vega]
ICGC DataPortalENSG00000104969
TCGA cBioPortalSGTA
AceView (NCBI)SGTA
Genatlas (Paris)SGTA
WikiGenes6449
SOURCE (Princeton)SGTA
Genetics Home Reference (NIH)SGTA
Genomic and cartography
GoldenPath hg38 (UCSC)SGTA  -     chr19:2754714-2783356 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SGTA  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblSGTA - 19p13.3 [CytoView hg19]  SGTA - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBISGTA [Mapview hg19]  SGTA [Mapview hg38]
OMIM603419   
Gene and transcription
Genbank (Entrez)AF368279 AF408399 AJ133129 AJ223828 AK293535
RefSeq transcript (Entrez)NM_003021
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SGTA
Cluster EST : UnigeneHs.203910 [ NCBI ]
CGAP (NCI)Hs.203910
Alternative Splicing GalleryENSG00000104969
Gene ExpressionSGTA [ NCBI-GEO ]   SGTA [ EBI - ARRAY_EXPRESS ]   SGTA [ SEEK ]   SGTA [ MEM ]
Gene Expression Viewer (FireBrowse)SGTA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6449
GTEX Portal (Tissue expression)SGTA
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43765   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43765  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43765
Splice isoforms : SwissVarO43765
PhosPhoSitePlusO43765
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)SGTA_dimer    TPR-contain_dom    TPR-like_helical_dom    TPR_1    TPR_repeat   
Domain families : Pfam (Sanger)SGTA_dimer (PF16546)    TPR_1 (PF00515)    TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam16546    pfam00515    pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)SGTA
DMDM Disease mutations6449
Blocks (Seattle)SGTA
PDB (SRS)2VYI    4CPG    4GOD    4GOE    4GOF   
PDB (PDBSum)2VYI    4CPG    4GOD    4GOE    4GOF   
PDB (IMB)2VYI    4CPG    4GOD    4GOE    4GOF   
PDB (RSDB)2VYI    4CPG    4GOD    4GOE    4GOF   
Structural Biology KnowledgeBase2VYI    4CPG    4GOD    4GOE    4GOF   
SCOP (Structural Classification of Proteins)2VYI    4CPG    4GOD    4GOE    4GOF   
CATH (Classification of proteins structures)2VYI    4CPG    4GOD    4GOE    4GOF   
SuperfamilyO43765
Human Protein AtlasENSG00000104969
Peptide AtlasO43765
HPRD04568
IPIIPI00013949   IPI00908410   
Protein Interaction databases
DIP (DOE-UCLA)O43765
IntAct (EBI)O43765
FunCoupENSG00000104969
BioGRIDSGTA
STRING (EMBL)SGTA
ZODIACSGTA
Ontologies - Pathways
QuickGOO43765
Ontology : AmiGOprotein binding  nucleus  cytoplasm  cytosol  biological_process  membrane  viral process  ubiquitin-dependent ERAD pathway  protein self-association  negative regulation of ER-associated ubiquitin-dependent protein catabolic process  positive regulation of ER-associated ubiquitin-dependent protein catabolic process  BAT3 complex binding  negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  cytosol  biological_process  membrane  viral process  ubiquitin-dependent ERAD pathway  protein self-association  negative regulation of ER-associated ubiquitin-dependent protein catabolic process  positive regulation of ER-associated ubiquitin-dependent protein catabolic process  BAT3 complex binding  negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process  
NDEx NetworkSGTA
Atlas of Cancer Signalling NetworkSGTA
Wikipedia pathwaysSGTA
Orthology - Evolution
OrthoDB6449
GeneTree (enSembl)ENSG00000104969
Phylogenetic Trees/Animal Genes : TreeFamSGTA
HOVERGENO43765
HOGENOMO43765
Homologs : HomoloGeneSGTA
Homology/Alignments : Family Browser (UCSC)SGTA
Gene fusions - Rearrangements
Fusion : MitelmanHAUS8/SGTA [19p13.11/19p13.3]  [t(19;19)(p13;p13)]  
Fusion : MitelmanSLC39A3/SGTA [19p13.3/19p13.3]  [t(19;19)(p13;p13)]  
Fusion: TCGAHAUS8 19p13.11 SGTA 19p13.3 PRAD
Fusion: TCGASLC39A3 19p13.3 SGTA 19p13.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSGTA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SGTA
dbVarSGTA
ClinVarSGTA
1000_GenomesSGTA 
Exome Variant ServerSGTA
ExAC (Exome Aggregation Consortium)SGTA (select the gene name)
Genetic variants : HAPMAP6449
Genomic Variants (DGV)SGTA [DGVbeta]
DECIPHERSGTA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSGTA 
Mutations
ICGC Data PortalSGTA 
TCGA Data PortalSGTA 
Broad Tumor PortalSGTA
OASIS PortalSGTA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSGTA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSGTA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SGTA
DgiDB (Drug Gene Interaction Database)SGTA
DoCM (Curated mutations)SGTA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SGTA (select a term)
intoGenSGTA
Cancer3DSGTA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603419   
Orphanet
MedgenSGTA
Genetic Testing Registry SGTA
NextProtO43765 [Medical]
TSGene6449
GENETestsSGTA
Target ValidationSGTA
Huge Navigator SGTA [HugePedia]
snp3D : Map Gene to Disease6449
BioCentury BCIQSGTA
ClinGenSGTA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6449
Chemical/Pharm GKB GenePA35727
Clinical trialSGTA
Miscellaneous
canSAR (ICR)SGTA (select the gene name)
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSGTA
EVEXSGTA
GoPubMedSGTA
iHOPSGTA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:30:52 CEST 2017

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