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SH2D2A (SH2 domain containing 2A)

Identity

Alias_namesSH2 domain protein 2A
Alias_symbol (synonym)TSAd
F2771
Other aliasSCAP
TSAD
VRAP
HGNC (Hugo) SH2D2A
LocusID (NCBI) 9047
Atlas_Id 56286
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 156776035 and ends at 156786640 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
IQGAP3 (1q22) / SH2D2A (1q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SH2D2A   10821
Cards
Entrez_Gene (NCBI)SH2D2A  9047  SH2 domain containing 2A
AliasesF2771; SCAP; TSAD; VRAP
GeneCards (Weizmann)SH2D2A
Ensembl hg19 (Hinxton)ENSG00000027869 [Gene_View]  chr1:156776035-156786640 [Contig_View]  SH2D2A [Vega]
Ensembl hg38 (Hinxton)ENSG00000027869 [Gene_View]  chr1:156776035-156786640 [Contig_View]  SH2D2A [Vega]
ICGC DataPortalENSG00000027869
TCGA cBioPortalSH2D2A
AceView (NCBI)SH2D2A
Genatlas (Paris)SH2D2A
WikiGenes9047
SOURCE (Princeton)SH2D2A
Genetics Home Reference (NIH)SH2D2A
Genomic and cartography
GoldenPath hg19 (UCSC)SH2D2A  -     chr1:156776035-156786640 -  1q23.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SH2D2A  -     1q23.1   [Description]    (hg38-Dec_2013)
EnsemblSH2D2A - 1q23.1 [CytoView hg19]  SH2D2A - 1q23.1 [CytoView hg38]
Mapping of homologs : NCBISH2D2A [Mapview hg19]  SH2D2A [Mapview hg38]
OMIM604514   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001161441 NM_001161442 NM_001161443 NM_001161444 NM_003975
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SH2D2A
Cluster EST : UnigeneHs.103527 [ NCBI ]
CGAP (NCI)Hs.103527
Alternative Splicing GalleryENSG00000027869
Gene ExpressionSH2D2A [ NCBI-GEO ]   SH2D2A [ EBI - ARRAY_EXPRESS ]   SH2D2A [ SEEK ]   SH2D2A [ MEM ]
Gene Expression Viewer (FireBrowse)SH2D2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9047
GTEX Portal (Tissue expression)SH2D2A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP31   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP31  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP31
Splice isoforms : SwissVarQ9NP31
PhosPhoSitePlusQ9NP31
Domaine pattern : Prosite (Expaxy)SH2 (PS50001)   
Domains : Interpro (EBI)SH2   
Domain families : Pfam (Sanger)SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00017   
Domain families : Smart (EMBL)SH2 (SM00252)  
Conserved Domain (NCBI)SH2D2A
DMDM Disease mutations9047
Blocks (Seattle)SH2D2A
SuperfamilyQ9NP31
Human Protein AtlasENSG00000027869
Peptide AtlasQ9NP31
HPRD05152
IPIIPI00099806   IPI00220388   IPI00936634   IPI00220389   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP31
IntAct (EBI)Q9NP31
FunCoupENSG00000027869
BioGRIDSH2D2A
STRING (EMBL)SH2D2A
ZODIACSH2D2A
Ontologies - Pathways
QuickGOQ9NP31
Ontology : AmiGOangiogenesis  SH3/SH2 adaptor activity  protein binding  cytoplasm  cytosol  signal transduction  cell proliferation  positive regulation of signal transduction  SH3 domain binding  cell differentiation  vascular endothelial growth factor receptor signaling pathway  
Ontology : EGO-EBIangiogenesis  SH3/SH2 adaptor activity  protein binding  cytoplasm  cytosol  signal transduction  cell proliferation  positive regulation of signal transduction  SH3 domain binding  cell differentiation  vascular endothelial growth factor receptor signaling pathway  
Pathways : KEGGVEGF signaling pathway   
NDEx NetworkSH2D2A
Atlas of Cancer Signalling NetworkSH2D2A
Wikipedia pathwaysSH2D2A
Orthology - Evolution
OrthoDB9047
GeneTree (enSembl)ENSG00000027869
Phylogenetic Trees/Animal Genes : TreeFamSH2D2A
HOVERGENQ9NP31
HOGENOMQ9NP31
Homologs : HomoloGeneSH2D2A
Homology/Alignments : Family Browser (UCSC)SH2D2A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH2D2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH2D2A
dbVarSH2D2A
ClinVarSH2D2A
1000_GenomesSH2D2A 
Exome Variant ServerSH2D2A
ExAC (Exome Aggregation Consortium)SH2D2A (select the gene name)
Genetic variants : HAPMAP9047
Genomic Variants (DGV)SH2D2A [DGVbeta]
DECIPHER (Syndromes)1:156776035-156786640  ENSG00000027869
CONAN: Copy Number AnalysisSH2D2A 
Mutations
ICGC Data PortalSH2D2A 
TCGA Data PortalSH2D2A 
Broad Tumor PortalSH2D2A
OASIS PortalSH2D2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH2D2A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSH2D2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SH2D2A
DgiDB (Drug Gene Interaction Database)SH2D2A
DoCM (Curated mutations)SH2D2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SH2D2A (select a term)
intoGenSH2D2A
Cancer3DSH2D2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604514   
Orphanet
MedgenSH2D2A
Genetic Testing Registry SH2D2A
NextProtQ9NP31 [Medical]
TSGene9047
GENETestsSH2D2A
Huge Navigator SH2D2A [HugePedia]
snp3D : Map Gene to Disease9047
BioCentury BCIQSH2D2A
ClinGenSH2D2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9047
Chemical/Pharm GKB GenePA35729
Clinical trialSH2D2A
Miscellaneous
canSAR (ICR)SH2D2A (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSH2D2A
EVEXSH2D2A
GoPubMedSH2D2A
iHOPSH2D2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:27:06 CET 2017

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