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SH2D2A (SH2 domain containing 2A)

Identity

Alias (NCBI)F2771
SCAP
TSAD
VRAP
HGNC (Hugo) SH2D2A
HGNC Alias symbTSAd
F2771
HGNC Alias nameT lymphocyte specific adaptor protein
 T cell specific adapter protein TSAd
 T cell specific adpater protein TSAd
HGNC Previous nameSH2 domain protein 2A
LocusID (NCBI) 9047
Atlas_Id 56286
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 156806243 and ends at 156816848 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IQGAP3 (1q22) / SH2D2A (1q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SH2D2A   10821
Cards
Entrez_Gene (NCBI)SH2D2A    SH2 domain containing 2A
AliasesF2771; SCAP; TSAD; VRAP
GeneCards (Weizmann)SH2D2A
Ensembl hg19 (Hinxton)ENSG00000027869 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000027869 [Gene_View]  ENSG00000027869 [Sequence]  chr1:156806243-156816848 [Contig_View]  SH2D2A [Vega]
ICGC DataPortalENSG00000027869
TCGA cBioPortalSH2D2A
AceView (NCBI)SH2D2A
Genatlas (Paris)SH2D2A
SOURCE (Princeton)SH2D2A
Genetics Home Reference (NIH)SH2D2A
Genomic and cartography
GoldenPath hg38 (UCSC)SH2D2A  -     chr1:156806243-156816848 -  1q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SH2D2A  -     1q23.1   [Description]    (hg19-Feb_2009)
GoldenPathSH2D2A - 1q23.1 [CytoView hg19]  SH2D2A - 1q23.1 [CytoView hg38]
ImmunoBaseENSG00000027869
Genome Data Viewer NCBISH2D2A [Mapview hg19]  
OMIM604514   
Gene and transcription
Genbank (Entrez)AF051325 AF097744 AJ000553 AK222737 AK313706
RefSeq transcript (Entrez)NM_001161441 NM_001161442 NM_001161443 NM_001161444 NM_003975
Consensus coding sequences : CCDS (NCBI)SH2D2A
Gene ExpressionSH2D2A [ NCBI-GEO ]   SH2D2A [ EBI - ARRAY_EXPRESS ]   SH2D2A [ SEEK ]   SH2D2A [ MEM ]
Gene Expression Viewer (FireBrowse)SH2D2A [ Firebrowse - Broad ]
GenevisibleExpression of SH2D2A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9047
GTEX Portal (Tissue expression)SH2D2A
Human Protein AtlasENSG00000027869-SH2D2A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP31   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP31  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP31
PhosPhoSitePlusQ9NP31
Domaine pattern : Prosite (Expaxy)SH2 (PS50001)   
Domains : Interpro (EBI)SH2    SH2_dom_sf    SH2D2A_SH2   
Domain families : Pfam (Sanger)SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00017   
Domain families : Smart (EMBL)SH2 (SM00252)  
Conserved Domain (NCBI)SH2D2A
SuperfamilyQ9NP31
AlphaFold pdb e-kbQ9NP31   
Human Protein Atlas [tissue]ENSG00000027869-SH2D2A [tissue]
HPRD05152
Protein Interaction databases
DIP (DOE-UCLA)Q9NP31
IntAct (EBI)Q9NP31
BioGRIDSH2D2A
STRING (EMBL)SH2D2A
ZODIACSH2D2A
Ontologies - Pathways
QuickGOQ9NP31
Ontology : AmiGOangiogenesis  protein binding  cytoplasm  cytosol  signal transduction  cell population proliferation  SH3 domain binding  cell differentiation  vascular endothelial growth factor receptor signaling pathway  
Ontology : EGO-EBIangiogenesis  protein binding  cytoplasm  cytosol  signal transduction  cell population proliferation  SH3 domain binding  cell differentiation  vascular endothelial growth factor receptor signaling pathway  
Pathways : KEGGVEGF signaling pathway   
NDEx NetworkSH2D2A
Atlas of Cancer Signalling NetworkSH2D2A
Wikipedia pathwaysSH2D2A
Orthology - Evolution
OrthoDB9047
GeneTree (enSembl)ENSG00000027869
Phylogenetic Trees/Animal Genes : TreeFamSH2D2A
Homologs : HomoloGeneSH2D2A
Homology/Alignments : Family Browser (UCSC)SH2D2A
Gene fusions - Rearrangements
Fusion : QuiverSH2D2A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH2D2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH2D2A
dbVarSH2D2A
ClinVarSH2D2A
MonarchSH2D2A
1000_GenomesSH2D2A 
Exome Variant ServerSH2D2A
GNOMAD BrowserENSG00000027869
Varsome BrowserSH2D2A
ACMGSH2D2A variants
VarityQ9NP31
Genomic Variants (DGV)SH2D2A [DGVbeta]
DECIPHERSH2D2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSH2D2A 
Mutations
ICGC Data PortalSH2D2A 
TCGA Data PortalSH2D2A 
Broad Tumor PortalSH2D2A
OASIS PortalSH2D2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH2D2A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSH2D2A
Mutations and Diseases : HGMDSH2D2A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSH2D2A
DgiDB (Drug Gene Interaction Database)SH2D2A
DoCM (Curated mutations)SH2D2A
CIViC (Clinical Interpretations of Variants in Cancer)SH2D2A
Cancer3DSH2D2A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604514   
Orphanet
DisGeNETSH2D2A
MedgenSH2D2A
Genetic Testing Registry SH2D2A
NextProtQ9NP31 [Medical]
GENETestsSH2D2A
Target ValidationSH2D2A
Huge Navigator SH2D2A [HugePedia]
ClinGenSH2D2A
Clinical trials, drugs, therapy
MyCancerGenomeSH2D2A
Protein Interactions : CTDSH2D2A
Pharm GKB GenePA35729
PharosQ9NP31
Clinical trialSH2D2A
Miscellaneous
canSAR (ICR)SH2D2A
HarmonizomeSH2D2A
DataMed IndexSH2D2A
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSH2D2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:30:59 CEST 2021

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