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SH2D4A (SH2 domain containing 4A)

Identity

Alias_namesregulatory subunit 38
Alias_symbol (synonym)FLJ20967
SH2A
PPP1R38
Other alias
HGNC (Hugo) SH2D4A
LocusID (NCBI) 63898
Atlas_Id 53879
Location 8p21.3  [Link to chromosome band 8p21]
Location_base_pair Starts at 19171487 and ends at 19253729 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SHANK3 (22q13.33) / SH2D4A (8p21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SH2D4A   26102
Cards
Entrez_Gene (NCBI)SH2D4A  63898  SH2 domain containing 4A
AliasesPPP1R38; SH2A
GeneCards (Weizmann)SH2D4A
Ensembl hg19 (Hinxton)ENSG00000104611 [Gene_View]  chr8:19171487-19253729 [Contig_View]  SH2D4A [Vega]
Ensembl hg38 (Hinxton)ENSG00000104611 [Gene_View]  chr8:19171487-19253729 [Contig_View]  SH2D4A [Vega]
ICGC DataPortalENSG00000104611
TCGA cBioPortalSH2D4A
AceView (NCBI)SH2D4A
Genatlas (Paris)SH2D4A
WikiGenes63898
SOURCE (Princeton)SH2D4A
Genetics Home Reference (NIH)SH2D4A
Genomic and cartography
GoldenPath hg19 (UCSC)SH2D4A  -     chr8:19171487-19253729 +  8p21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SH2D4A  -     8p21.3   [Description]    (hg38-Dec_2013)
EnsemblSH2D4A - 8p21.3 [CytoView hg19]  SH2D4A - 8p21.3 [CytoView hg38]
Mapping of homologs : NCBISH2D4A [Mapview hg19]  SH2D4A [Mapview hg38]
OMIM614968   
Gene and transcription
Genbank (Entrez)AK024620 AK024799 AK225052 AK293301 AY190323
RefSeq transcript (Entrez)NM_001174159 NM_001174160 NM_022071
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)SH2D4A
Cluster EST : UnigeneHs.303208 [ NCBI ]
CGAP (NCI)Hs.303208
Alternative Splicing GalleryENSG00000104611
Gene ExpressionSH2D4A [ NCBI-GEO ]   SH2D4A [ EBI - ARRAY_EXPRESS ]   SH2D4A [ SEEK ]   SH2D4A [ MEM ]
Gene Expression Viewer (FireBrowse)SH2D4A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63898
GTEX Portal (Tissue expression)SH2D4A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H788   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H788  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H788
Splice isoforms : SwissVarQ9H788
PhosPhoSitePlusQ9H788
Domaine pattern : Prosite (Expaxy)SH2 (PS50001)   
Domains : Interpro (EBI)SH2   
Domain families : Pfam (Sanger)SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00017   
Domain families : Smart (EMBL)SH2 (SM00252)  
Conserved Domain (NCBI)SH2D4A
DMDM Disease mutations63898
Blocks (Seattle)SH2D4A
SuperfamilyQ9H788
Human Protein AtlasENSG00000104611
Peptide AtlasQ9H788
HPRD08340
IPIIPI00100731   IPI00956622   IPI00977743   
Protein Interaction databases
DIP (DOE-UCLA)Q9H788
IntAct (EBI)Q9H788
FunCoupENSG00000104611
BioGRIDSH2D4A
STRING (EMBL)SH2D4A
ZODIACSH2D4A
Ontologies - Pathways
QuickGOQ9H788
Ontology : AmiGOprotein binding  cytoplasm  negative regulation of phosphatase activity  phosphatase binding  
Ontology : EGO-EBIprotein binding  cytoplasm  negative regulation of phosphatase activity  phosphatase binding  
NDEx NetworkSH2D4A
Atlas of Cancer Signalling NetworkSH2D4A
Wikipedia pathwaysSH2D4A
Orthology - Evolution
OrthoDB63898
GeneTree (enSembl)ENSG00000104611
Phylogenetic Trees/Animal Genes : TreeFamSH2D4A
HOVERGENQ9H788
HOGENOMQ9H788
Homologs : HomoloGeneSH2D4A
Homology/Alignments : Family Browser (UCSC)SH2D4A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH2D4A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH2D4A
dbVarSH2D4A
ClinVarSH2D4A
1000_GenomesSH2D4A 
Exome Variant ServerSH2D4A
ExAC (Exome Aggregation Consortium)SH2D4A (select the gene name)
Genetic variants : HAPMAP63898
Genomic Variants (DGV)SH2D4A [DGVbeta]
DECIPHER (Syndromes)8:19171487-19253729  ENSG00000104611
CONAN: Copy Number AnalysisSH2D4A 
Mutations
ICGC Data PortalSH2D4A 
TCGA Data PortalSH2D4A 
Broad Tumor PortalSH2D4A
OASIS PortalSH2D4A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH2D4A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSH2D4A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SH2D4A
DgiDB (Drug Gene Interaction Database)SH2D4A
DoCM (Curated mutations)SH2D4A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SH2D4A (select a term)
intoGenSH2D4A
Cancer3DSH2D4A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614968   
Orphanet
MedgenSH2D4A
Genetic Testing Registry SH2D4A
NextProtQ9H788 [Medical]
TSGene63898
GENETestsSH2D4A
Huge Navigator SH2D4A [HugePedia]
snp3D : Map Gene to Disease63898
BioCentury BCIQSH2D4A
ClinGenSH2D4A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63898
Chemical/Pharm GKB GenePA134891945
Clinical trialSH2D4A
Miscellaneous
canSAR (ICR)SH2D4A (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSH2D4A
EVEXSH2D4A
GoPubMedSH2D4A
iHOPSH2D4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:19:10 CEST 2017

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