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SH2D4B (SH2 domain containing 4B)

Identity

Alias (NCBI)-
HGNC (Hugo) SH2D4B
LocusID (NCBI) 387694
Atlas_Id 73193
Location 10q23.1  [Link to chromosome band 10q23]
Location_base_pair Starts at 80537902 and ends at 80646560 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SH2D4B   31440
Cards
Entrez_Gene (NCBI)SH2D4B    SH2 domain containing 4B
Aliases
GeneCards (Weizmann)SH2D4B
Ensembl hg19 (Hinxton)ENSG00000178217 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178217 [Gene_View]  ENSG00000178217 [Sequence]  chr10:80537902-80646560 [Contig_View]  SH2D4B [Vega]
ICGC DataPortalENSG00000178217
TCGA cBioPortalSH2D4B
AceView (NCBI)SH2D4B
Genatlas (Paris)SH2D4B
SOURCE (Princeton)SH2D4B
Genetics Home Reference (NIH)SH2D4B
Genomic and cartography
GoldenPath hg38 (UCSC)SH2D4B  -     chr10:80537902-80646560 +  10q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SH2D4B  -     10q23.1   [Description]    (hg19-Feb_2009)
GoldenPathSH2D4B - 10q23.1 [CytoView hg19]  SH2D4B - 10q23.1 [CytoView hg38]
ImmunoBaseENSG00000178217
Genome Data Viewer NCBISH2D4B [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK091518 AK123885 AK123978
RefSeq transcript (Entrez)NM_001145719 NM_001388272 NM_207372
Consensus coding sequences : CCDS (NCBI)SH2D4B
Gene ExpressionSH2D4B [ NCBI-GEO ]   SH2D4B [ EBI - ARRAY_EXPRESS ]   SH2D4B [ SEEK ]   SH2D4B [ MEM ]
Gene Expression Viewer (FireBrowse)SH2D4B [ Firebrowse - Broad ]
GenevisibleExpression of SH2D4B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)387694
GTEX Portal (Tissue expression)SH2D4B
Human Protein AtlasENSG00000178217-SH2D4B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5SQS7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5SQS7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5SQS7
PhosPhoSitePlusQ5SQS7
Domaine pattern : Prosite (Expaxy)SH2 (PS50001)   
Domains : Interpro (EBI)SH2    SH2_dom_sf    SH2D4B_SH2   
Domain families : Pfam (Sanger)SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00017   
Domain families : Smart (EMBL)SH2 (SM00252)  
Conserved Domain (NCBI)SH2D4B
SuperfamilyQ5SQS7
AlphaFold pdb e-kbQ5SQS7   
Human Protein Atlas [tissue]ENSG00000178217-SH2D4B [tissue]
HPRD18050
Protein Interaction databases
DIP (DOE-UCLA)Q5SQS7
IntAct (EBI)Q5SQS7
BioGRIDSH2D4B
STRING (EMBL)SH2D4B
ZODIACSH2D4B
Ontologies - Pathways
QuickGOQ5SQS7
Ontology : AmiGOcytoplasm  
Ontology : EGO-EBIcytoplasm  
NDEx NetworkSH2D4B
Atlas of Cancer Signalling NetworkSH2D4B
Wikipedia pathwaysSH2D4B
Orthology - Evolution
OrthoDB387694
GeneTree (enSembl)ENSG00000178217
Phylogenetic Trees/Animal Genes : TreeFamSH2D4B
Homologs : HomoloGeneSH2D4B
Homology/Alignments : Family Browser (UCSC)SH2D4B
Gene fusions - Rearrangements
Fusion : QuiverSH2D4B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH2D4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH2D4B
dbVarSH2D4B
ClinVarSH2D4B
MonarchSH2D4B
1000_GenomesSH2D4B 
Exome Variant ServerSH2D4B
GNOMAD BrowserENSG00000178217
Varsome BrowserSH2D4B
ACMGSH2D4B variants
VarityQ5SQS7
Genomic Variants (DGV)SH2D4B [DGVbeta]
DECIPHERSH2D4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSH2D4B 
Mutations
ICGC Data PortalSH2D4B 
TCGA Data PortalSH2D4B 
Broad Tumor PortalSH2D4B
OASIS PortalSH2D4B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH2D4B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSH2D4B
Mutations and Diseases : HGMDSH2D4B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSH2D4B
DgiDB (Drug Gene Interaction Database)SH2D4B
DoCM (Curated mutations)SH2D4B
CIViC (Clinical Interpretations of Variants in Cancer)SH2D4B
Cancer3DSH2D4B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSH2D4B
MedgenSH2D4B
Genetic Testing Registry SH2D4B
NextProtQ5SQS7 [Medical]
GENETestsSH2D4B
Target ValidationSH2D4B
Huge Navigator SH2D4B [HugePedia]
ClinGenSH2D4B
Clinical trials, drugs, therapy
MyCancerGenomeSH2D4B
Protein Interactions : CTDSH2D4B
Pharm GKB GenePA134943660
PharosQ5SQS7
Clinical trialSH2D4B
Miscellaneous
canSAR (ICR)SH2D4B
HarmonizomeSH2D4B
DataMed IndexSH2D4B
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSH2D4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:20:25 CEST 2021

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